Displaying publications 3421 - 3440 of 8055 in total

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  1. Chin LY, Zainal Z, Hussein MZ, Tee TW
    J Nanosci Nanotechnol, 2011 Jun;11(6):4900-9.
    PMID: 21770120
    The fabrication of TiO2 nanotubes (TNT) was carried out by electrochemical anodization of Ti in aqueous electrolyte containing NH4F. The effect of electrolyte pH, applied voltage, fluoride concentration and anodization duration on the formation of TNT was investigated. It was observed that self-organized TNT can be formed by adjusting the electrolyte to pH 2-4 whereby applied voltage of 10-20 V can be performed to produce highly ordered, well-organized TNT. At 20 V, TNT can be fabricated in the concentration range of 0.07 M to 0.20 M NH4F. Higher fluoride concentration leads to etching of Ti surface and reveals the Ti grain boundaries. The prepared TNT films also show an increase in depth and in size with time and the growth of TNT films reach a steady state after 120 minutes. The morphology and geometrical aspect of the TNT would be an important factor influencing the photoelectrochemical response, with higher photocurrent response is generally associated with thicker layer of TNT. Consequently, one can tailor the resulting TNT to desired surface morphologies by simply manipulating the electrochemical parameters for wide applications such as solar energy conversion and photoelectrocatalysis.
  2. Khor Ee IH, Chor Lip HT, Muniandy J
    ANZ J Surg, 2021 Jul 29.
    PMID: 34324784 DOI: 10.1111/ans.17107
  3. Jin-Poi T, Shatriah I, Khairy-Shamel ST, Zunaina E
    Clin Ophthalmol, 2013;7:839-42.
    PMID: 23674886 DOI: 10.2147/OPTH.S42122
    A decrease in the anterior capsule opening after cataract surgery has been observed in eyes with weakened lens zonules. It commonly occurs in diabetes mellitus, uveitis, pseudoexfoliation syndrome, high myopia, and elderly patients. Herein, we report the case of a middle-aged man with advanced retinitis pigmentosa who developed a rapid contraction of the anterior capsule after an uneventful phacoemulsification surgery that resulted in severe visual loss during the early postoperative period.
  4. Hookham B, Shau-Hwai AT, Dayrat B, Hintz W
    Trop Life Sci Res, 2014 Aug;25(1):1-12.
    PMID: 25210584 MyJurnal
    THE DIVERSITIES OF MANGROVE TREES AND OF THEIR ASSOCIATED GASTROPODS WERE ASSESSED FOR TWO MANGROVE REGIONS ON THE WEST COAST OF PENINSULAR MALAYSIA: Langkawi Island and Sungai Merbok. The mangrove area sampled on Langkawi Island was recently logged and replanted, whereas the area sampled in Sungai Merbok was part of a protected nature reserve. Mangrove and gastropod diversity were assessed in four 50 m(2) (10 × 5 m) sites per region. The species richness (S), Shannon Index (H') and Evenness Index (J') were calculated for each site, and the mean S, H' and J' values were calculated for each region. We report low tree and gastropod S, H' and J' values in all sites from both regions. For Langkawi Island, the mean S, H' and J' values for mangrove trees were S = 2.00±0, H' = 0.44±0.17 and J' = 0.44±0.17; the mean S, H' and J' values for gastropods were S = 4.00±1.63, H' = 0.96±0.41 and J' = 0.49±0.06. In Sungai Merbok, the mean S, H' and J' values for mangrove trees were S = 1.33±0.58, H' = 0.22±0.39 and J' = 0.22 ±0.39; the mean S, H' and J' values for gastropods were S = 4.75±2.22, H' = 1.23±0.63 and J' = 0.55±0.12. This study emphasises the need for baseline biodiversity measures to be established in mangrove ecosystems to track the impacts of anthropogenic disturbances and to inform management and restoration efforts.
  5. Yin TT, Pin UL, Ghazali AH
    Trop Life Sci Res, 2015 Apr;26(1):101-10.
    PMID: 26868594 MyJurnal
    The production of nitrogenase enzyme and auxins by free living diazotrophs has the potential to influence the growth of host plants. In this study, diazotrophs were grown in the presence of various concentrations of nitogen (N) to determine the optimal concentration of N for microbial growth stimulation, promotion of gaseous N (N2) fixation, and phytohormone production. Therefore, we investigate whether different levels of N supplied to Herbaspirillum seropedicae (Z78) have significant effects on nitrogenase activity and auxin production. The highest nitrogenase activity and the lowest auxin production of H. seropedicae (Z78) were both recorded at 0 gL(-1) of NH4Cl. Higher levels of external N caused a significant decrease in the nitrogenase activity and an increased production of auxins. In a subsequent test, two different inoculum sizes of Z78 (10(6) and 10(12) cfu/ml) were used to study the effect of different percentages of acetylene on nitrogenase activity of the inoculum via the acetylene reduction assay (ARA). The results showed that the optimal amount of acetylene required for nitrogenase enzyme activity was 5% for the 10(6) cfu/ml inoculum, whereas the higher inoculum size (10(12) cfu/ml) required at least 10% of acetylene for optimal nitrogenase activity. These findings provide a clearer understanding of the effects of N levels on diazotrophic nitrogenase activity and auxin production, which are important factors influencing plant growth.
  6. Leh TY, Yong CSY, Nulit R, Abdullah JO
    Trop Life Sci Res, 2019 Jan;30(1):149-159.
    PMID: 30847038 MyJurnal DOI: 10.21315/tlsr2019.30.1.9
    Stevia rebaudiana, a perennial herb native to northeastern Paraguay, has gained immense attention globally over the recent decades due to the natural sweetness of its leaves. Like in most plants, this particular species contains high amount of secondary metabolites, thus rendering the isolation of high quality and quantity RNA extract for molecular applications rather challenging. An effective, high-yield and high-quality RNA isolation protocol for this economically important plant species was devised here based on the cetyltrimethylammonium bromide (CTAB) extraction method, with an additional genomic DNA (gDNA) removal step. DNA and other contaminants that may affect downstream applications were effectively removed. Our results exhibited that RNA samples isolated from the leaves and stems of Stevia rebaudiana using this improvised method are high in integrity and quality with RNA integrity number (RIN) of more than 8 and low in contaminants.
  7. Farrukh MJ, Makmor-Bakry M, Hatah E, Jan TH
    BMC Complement Med Ther, 2021 Feb 04;21(1):50.
    PMID: 33541336 DOI: 10.1186/s12906-021-03224-2
    BACKGROUND: The aim of this study was to assess the knowledge, attitude, and practice of complementary and alternative medicine (CAM) and its impact on antiepileptic drug (AED) adherence among patients with epilepsy.

    METHODS: A cross-sectional study was carried out on 100 epilepsy patients, aged 18 years or older that did not have any physical or psychiatric illness. A patient-administered questionnaire was used to assess their knowledge, attitude towards, practice, and perceived effectiveness (KAPP) of CAM. Established adherence assessment tools were used to determine patient medication adherence.

    RESULTS: The prevalence of CAM usage was found to be at 58%. CAM was used more frequently by males (n = 32, 60.4%) than by females (n = 26, 55.3%; p = 0.609). The most commonly used CAM included vitamins and minerals (36%), ginseng (16%), antioxidants (15%), and acupuncture (12%). A significant number of patients had low knowledge of (59%) and a positive attitude (54%) toward complementary and alternative medicine. Main reasons for using CAM were a lower price, better availability, and inadequate seizure control by AEDs. About 43% of the patients who used CAM informed their doctor. Prevalence of non-adherence to AED therapy was found to be 68%. A significant association was found between non-adherence and CAM usage (p 

  8. Aun TT, Salleh NM, Ali UFM, Manan NSA
    Crit Rev Anal Chem, 2021 Sep 03.
    PMID: 34477020
    Non-enzymatic glucose sensors based on the use of copper and its oxides have emerged as promising candidates to replace enzymatic glucose sensors owing to their stability, ease of fabrication, and superior sensitivity. This review explains the theories of the mechanism of glucose oxidation on copper transition metal electrodes. It also presents an overview on the development of among the best non-enzymatic copper-based glucose sensors in the past 10 years. A brief description of methods, interesting findings, and important performance parameters are provided to inspire the reader and researcher to create new improvements in sensor design. Finally, several important considerations that pertain to the nano-structuring of the electrode surface is provided.
  9. Shahrul Azmin, Tan, Eng Liang, Law, Zhe Kang, Remli Rabani, Wan Yahya Nafisah, Sahathevan, Ramesh, et al.
    Neurology Asia, 2016;21(2):137-143.
    MyJurnal
    Background: Impulse control behaviours are repetitive and excessive activities that may be sub-syndromal and not fulfil the criteria for impulse control disorder. These activities have potential to negatively impact on the daily lives of sufferers. We conducted a study to investigate the prevalence of impulse control behaviours and its associated features in Parkinson’s disease in our population. Methods: We conducted a prospective cross-sectional study on consecutive patients attending neurology clinic. Inclusion criteria include idiopathic Parkinson’s disease patients with Hoehn & Yahr stage I-IV. Eighty patients were enrolled and screened for impulse control behaviours using the Questionnaire for Impulsive-Compulsive Disorder for Parkinson’s disease (QUIP). Results: Prevalence of impulse control behaviours among our cohort was 11.3%; the features significantly associated with it were higher level of education (p=0.02), advanced stage of disease (p=0.03) and higher levodopa dosage (p= 0.01). The commonest impulse control behaviour in our cohort was compulsive medication use (7.5%), followed by hobbyism (6.3%), hypersexuality (5%), compulsive buying (3.75%), punding (2.5%), walkabout (2.5%), compulsive eating (1.25%) and pathological gambling (1.3%).
    Conclusions: There is an association between impulse control behaviour and higher levodopa dosage in a study on patients with Parkinson’s disease in Malaysia. We also found a low prevalence of pathological gambling as compared to studies performed in the West.
    Study site: Neurology clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia
  10. Ling TH, Zakaria AF, Abdullah AT
    J Orthop Surg (Hong Kong), 2017 01;25(1):2309499017690459.
    PMID: 28228050 DOI: 10.1177/2309499017690459
    Neck manipulation is associated with spinal cord injury. However, occurrence of such cases is infrequent. This article presents a 33-year-old gentleman who sustained acute tetraplegia after neck manipulation. The aim of this case report is to create awareness that vigorous neck manipulation could cause injury to the spinal cord.
  11. Mahadev V, Dharmalingam SK, Tan D, Narasimha, Loh CW, Tschang TT
    Med J Malaysia, 1977 Jun;31(4):331-7.
    PMID: 927242
  12. Tai, Sharon Mei-Ling, Tan, Hong-Yien, Yong, Yean-Kong, Esaki M. Shankar, Yap, Jun-Fai, Tan, Chong Tin, et al.
    Neurology Asia, 2017;22(3):209-220.
    MyJurnal
    Background: Tuberculous meningitis is a life-threatening manifestation resulting from infection
    by Mycobacterium tuberculosis, especially in the developing countries. The molecular aspects of
    pathogenesis of tuberculous meningitis remain poorly understood. We evaluated the correlation of
    cerebrospinal fluid (CSF) and serum cytokine levels with the clinical outcome of 15 HIV-negative
    patients with tuberculous meningitis. We also assessed the association of CSF and serum cytokines
    with neuroimaging of brain findings in the patients.

    Methods: The prospective longitudinal study was
    conducted at the University Malaya Medical Centre between 2012 and 2014. Neuroimaging of the
    brain was performed and the findings of leptomeningeal enhancement, hydrocephalus, tuberculoma,
    infarcts and vasculopathy were recorded. The CSF and serum specimens were analyzed for IL-1ß,
    IL-8, IL-10, IL-18, IP-10, IFN-γ, MCP-1, TGF-ß, VEGF, TNF- α, IL-18BPa and MMP-9. The clinical
    outcome was graded at 3 months based on Modified Rankin scale (mRS).

    Results: On admission and
    at one month of anti-tuberculosis treatment, the CSF levels of IL-8, IL-1β, IP-10, IFN-γ and VEGF
    were elevated in all of the patients. Serum IP-10, MCP-1, IL-1β and IL-8 levels were increased on
    admission and at one month of anti-tuberculosis treatment. There were statistically significant differences
    between good and poor outcome (mRS at 3 months) for CSF IFN-γ (p=0.033), CSF IL-10 (p=0.033)
    and serum VEGF (p=0.033) at one month of treatment. None of the patients showed any association
    between CSF and serum cytokines on admission and at one month of anti-tuberculosis treatment with
    neuro-radiological findings.

    Conclusion: The CSF cytokine levels were not related to TBM disease severity on admission, and
    changes on MRI/CT scans. CSF levels of IFN-γ and IL-10 at one month of anti-tuberculosis treatment
    were associated with clinical outcome at 3 months. CSF cytokine levels on admission were not
    associated with the clinical outcome.
  13. Gnanaraj C, Shah MD, Song TT, Iqbal M
    Biomed Pharmacother, 2017 Aug;92:1010-1022.
    PMID: 28609838 DOI: 10.1016/j.biopha.2017.06.014
    Plants have been consumed in medicinal practices for centuries. Lygodium microphyllum (Cav.) R.Br. (Lygodiaceae), also known as Old World Climbing Fern, is a medicinal plant used by local communities in Sabah for skin and dysentery ailments. This study aims to test aqueous extract of L. microphyllum leaves for hepatoprotective and immunosuppressive activity in rats. Animal studies were carried out to evaluate hepatoprotection of aqueous extract of L. microphyllum at different doses (200, 400 and 600mg/kg b.w.) against carbon tetrachloride (CCl4)-mediated liver injury and histopathological alterations. Total phenolic content in aqueous extract of L. microphyllum leaves was 206.38±9.62mg gallic acid equivalent/g. The inhibitory concentration (IC50) for free radical scavenging activity of L. microphyllum was reached at a concentration of 65μg/ml.L. microphyllum was able to prevent the increase in levels of serum alanine aminotransferase, serum aspartate aminotransferase and hepatic malondialdehyde formation in a dose-dependent manner. Immunohistochemical results evidenced the suppression of oxidative stress markers (4-hydroxynonenal, 8-hydroxydeoxyguanosine) and pro-inflammatory cytokines (Tumor Necrosis Factor-α, Interleukin-6, Prostaglandin E2). Histopathological and hepatocyte ultrastructural alterations showed protective effects by L. microphyllum against CCl4-mediated oxidative stress. Hepatoprotective mechanism of L. microphyllum can be attributed to its antioxidative effects through protection of ultrastructural organelles.
  14. Osman A, Wan Chuan T, Ab Rahman J, Via G, Tavazzi G
    Eur J Emerg Med, 2018 Oct;25(5):322-327.
    PMID: 28509710 DOI: 10.1097/MEJ.0000000000000471
    OBJECTIVE: The aim of this study was to evaluate a novel pericardiocentesis technique using an in-plane parasternal medial-to-lateral approach with the use of a high-frequency probe in patients with cardiac tamponade.

    BACKGROUND: Echocardiography is pivotal in the diagnosis of pericardial effusion and tamponade physiology. Ultrasound guidance for pericardiocentesis is currently considered the standard of care. Several approaches have been described recently, which differ mainly on the site of puncture (subxiphoid, apical, or parasternal). Although they share the use of low-frequency probes, there is absence of complete control of needle trajectory and real-time needle visualization. An in-plane and real-time technique has only been described anecdotally.

    METHODS AND RESULTS: A retrospective analysis of 11 patients (63% men, mean age: 37.7±21.2 years) presenting with cardiac tamponade admitted to the tertiary-care emergency department and treated with parasternal medial-to-lateral in-plane pericardiocentesis was carried out. The underlying causes of cardiac tamponade were different among the population. All the pericardiocentesis were successfully performed in the emergency department, without complications, relieving the hemodynamic instability. The mean time taken to perform the eight-step procedure was 309±76.4 s, with no procedure-related complications.

    CONCLUSION: The parasternal medial-to-lateral in-plane pericardiocentesis is a new technique theoretically free of complications and it enables real-time monitoring of needle trajectory. For the first time, a pericardiocentesis approach with a medial-to-lateral needle trajectory and real-time, in-plane, needle visualization was performed in a tamponade patient population.

  15. Wan Azman WN, Omar J, Koon TS, Tuan Ismail TS
    Oman Med J, 2019 Mar;34(2):94-98.
    PMID: 30918601 DOI: 10.5001/omj.2019.19
    Pre-analytical quality in clinical chemistry testing is as important as analytical and post-analytical quality. The most prevalent pre-analytical interference and a major source of error producing unreliable laboratory test results is hemolysis of blood samples. In vitro hemolysis may be due to the blood withdrawal technique or sample handling whereas in vivo hemolysis can originate from acquired, hereditary, or iatrogenic conditions and is not technique dependent. Interpreting in vivo or in vitro hemolysis requires clinicians to supply reliable clinical history and findings. Even then, to reject or release the result with interpretation is still under debate. Thus, hemolyzed specimens are a serious pre-analytical problem calling for well-designed and strictly implemented laboratory guidelines. The aim of this non-systematic review (addressed to healthcare professionals) was to highlight the challenges in identifying and rejecting hemolysis specimens.
  16. Ghanimi Zamli AK, Chew-Ean T, Wan Hitam WH
    Cureus, 2019 Apr 11;11(4):e4436.
    PMID: 31245223 DOI: 10.7759/cureus.4436
    Altitudinal visual field defect is a rare presentation of retrochiasmal lesion especially when bilateral visual fields were affected. In fact, bilateral inferior altitudinal visual field defect (BIAVFD) usually occurred in patients who survived a gunshot injury to the occipital lobe or as a direct trauma to the brain. We report a rare case of BIAVFD secondary to occipital meningioma. A high index of suspicion enables timely investigation and diagnosis when dealing with atypical presentation of intracranial meningioma.
  17. Beng TB, Kotani Y, Sia U, Gonchar I
    Asian Spine J, 2019 10;13(5):809-814.
    PMID: 31154702 DOI: 10.31616/asj.2018.0283
    Study Design: Retrospective clinical study on the indirect decompressive effect of oblique lateral interbody fusion (OLIF) for adult spinal deformity.

    Purpose: To evaluate the effect of interbody distraction by OLIF for the treatment of adult spinal deformity.

    Overview of Literature: Adult spinal deformity with symptomatic stenosis has been addressed conventionally using a direct posterior decompression approach with fusion. However, stenotic symptoms can also be alleviated indirectly through restoration of intervertebral and foraminal heights and correction of spinal alignment.

    Methods: Twenty-eight patients with adult spinal deformity underwent OLIF combined with modified cortical bone trajectory screws at 94 lumbar levels with neuromonitoring. The patients were divided into three groups based on their preoperative lumbar lordosis: group A, <0°; group B, 0°-20°; and group C, >20°. The cross-sectional area (CSA) of the thecal sac was measured preoperatively and postoperatively on axial magnetic resonance images. Differences in CSA were evaluated, and the relationship between the CSA extension ratio and preoperative CSA was assessed. Changes in disc height and segmental disc angle were measured from plain radiographs.

    Results: OLIFs were performed successfully without neural complications. In group A, the mean CSA increased from 120.6 mm2 preoperatively to 148.5 mm2 postoperatively (p <0.001). The mean CSA for group B increased from 120.1 mm2 preoperatively to 154.4 mm2 postoperatively (p <0.001). Group C had an increase in mean CSA from 114.7 mm2 preoperatively to 160.7 mm2 postoperatively (p <0.001). The mean CSA enlargement ratio was 27.5%, 32.1%, and 60.4% in groups A, B, and C, respectively. The mean CSA extension ratio was inversely correlated with preoperative CSA.

    Conclusions: The effect of indirect neural decompression in adult spinal deformity with OLIF varies with the degree of preoperative lumbar lordosis.

  18. Mahmud I, Sultana S, Rahman A, Ramayah T, Cheng Ling T
    Waste Manag Res, 2020 Dec;38(12):1438-1449.
    PMID: 32364437 DOI: 10.1177/0734242X20914753
    Each year Bangladesh produces around 400,000 metric tonnes of e-waste. E-waste accumulation is expected to increase by 20% annually. In order to facilitate e-waste recycling, it is crucial to identify the factors. In this study, building on the stimulus-organism-response framework, we develop a research model to explore the effect of information publicity, ascription of responsibility and convenience of recycling on the recycling attitude, subjective norm, personal norm and perceived behaviour control which lead to recycling intention. Data were gathered from 127 small and medium electronics store managers. The structural equation modelling technique was used to test the paths. The result suggests a significant influence of the element of stimulus (S) on the element of organism (O). The relationship between the element of organism (O) and the element of response (R) is partial. This paper contributes to the body of work dedicated to helping us better understand the recycling behaviour from the stimulus-organism-response perspective. From the viewpoint of practice, this research sheds light on some of the challenges that the implementer might face when making strategy and policy for e-waste management in Bangladesh.
  19. Sen CJ, Samad NHA, Huei TJ, Peng LE
    J Prim Health Care, 2021 Sep;13(3):283-286.
    PMID: 34588112 DOI: 10.1071/HC21084
    INTRODUCTION An intrauterine contraceptive device (IUCD) is a common contraception method used for family planning. IUCD erosion into adjacent organs is a rare but serious complication of IUCD use. CASE PRESENTATION A 41-year-old female presented to us with a leaking left ectopic pregnancy. Emergency laparotomy and left salpingectomy were performed. A copper ICUD was found intraperitoneally and part of it had completely eroded into the sigmoid colon. Sigmoid colotomy was performed and the IUCD was removed successfully. Further history revealed that the patient had her IUCD inserted 12 years previously but was forgotten. The patient was discharged well after 4 days of admission. DISCUSSION Erosion of an IUCD into the colon is uncommon and may be asymptomatic or present with bowel perforation and obstruction. There should be a high index of suspicion for pregnancy occurring among women post-IUCD insertion. A misplaced IUCD can cause chronic inflammation of the fallopian tube, which may alter tubal functionality and increase the risk of ectopic pregnancy. Family planning is commonly done in primary health care. Primary care education and counselling are essential to improve awareness of fertile women to prevent similar complications. Periodic examination of IUCD string either by users or primary health-care practitioners is crucial. Ultrasound can be advocated if there are difficulties with the insertion. An abdominal radiograph is useful and should be performed in the case of missing IUCDs.
  20. Tong TK, Shan G, Sibangun FJ, Keung BLD
    IDCases, 2021;26:e01295.
    PMID: 34646734 DOI: 10.1016/j.idcr.2021.e01295
    Background: Melioidosis-related mycotic aneurysm (MA) is rare but a potentially life-threatening disease with high morbidity and mortality rate.

    Case presentation: We report a case series of mycotic aneurysm caused by Burkholderia pseudomallei and the subsequent outcomes. Here, we illustrate their clinical characteristics, laboratory results, radiological findings, mode of therapies and clinical outcomes.

    Conclusion: Melioidosis-associated MA may manifest in an atypical presentation. Its outcome is often lethal if antimicrobial therapy and surgical intervention are not offered promptly.

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