Displaying publications 61 - 80 of 314 in total

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  1. Savage AE, Grismer LL, Anuar S, Onn CK, Grismer JL, Quah E, et al.
    Ecohealth, 2011 Mar;8(1):121-8.
    PMID: 21541819 DOI: 10.1007/s10393-011-0685-y
    The fungal pathogen Batrachochytrium dendrobatidis (Bd) infects amphibians on every continent where they occur and is linked to the decline of over 200 amphibian species worldwide. At present, only three published Bd surveys exist for mainland Asia, and Bd has been detected in South Korea alone. In this article, we report the first survey for Bd in Peninsular Malaysia. We swabbed 127 individuals from the six amphibian families that occur on Peninsular Malaysia, including two orders, 27 genera, and 47 species. We detected Bd on 10 out of 127 individuals from four of five states and five of 11 localities, placing the 95% confidence interval for overall prevalence at 4-14%. We detected no variation in Bd prevalence among regions, elevations, or taxonomic groups. The infection intensity ranged from 1 to 157,000 genome equivalents. The presence of Bd infections in native species without clinical signs of disease suggests that Bd may be endemic to the region. Alternately, Bd may have been introduced from non-native amphibians because of the substantial amphibian food trade in Peninsular Malaysia. Under both scenarios, management efforts should be implemented to limit the spread of non-native Bd and protect the tremendous amphibian diversity in Peninsular Malaysia.
  2. Ord TJ, Klomp DA, Summers TC, Diesmos A, Ahmad N, Das I
    Ecol Lett, 2021 Sep;24(9):1750-1761.
    PMID: 34196091 DOI: 10.1111/ele.13773
    Convergence in communication appears rare compared with other forms of adaptation. This is puzzling, given communication is acutely dependent on the environment and expected to converge in form when animals communicate in similar habitats. We uncover deep-time convergence in territorial communication between two groups of tropical lizards separated by over 140 million years of evolution: the Southeast Asian Draco and Caribbean Anolis. These groups have repeatedly converged in multiple aspects of display along common environmental gradients. Robot playbacks to free-ranging lizards confirmed that the most prominent convergence in display is adaptive, as it improves signal detection. We then provide evidence from a sample of the literature to further show that convergent adaptation among highly divergent animal groups is almost certainly widespread in nature. Signal evolution is therefore curbed towards the same set of adaptive solutions, especially when animals are challenged with the problem of communicating effectively in noisy environments.
  3. Tan XT, Amran FB, Thayan R, Ahmad N, Jaafar R, Haron R, et al.
    Electrophoresis, 2017 09;38(17):2141-2149.
    PMID: 28524240 DOI: 10.1002/elps.201600471
    Leptospirosis is an emerging zoonotic infectious disease in Malaysia. The symptoms of leptospirosis vary from mild nonspecific flu-like illness to a severe condition which is usually associated with serious complication and fatality. To study the protein expression profile of mild and severe leptospirosis, 15 paired sera were collected from the patients who were mildly infected and following that progressed to severe stage. The proteome profiles of mild and severe cases were studied using 2DE analysis in combination with LC-MS/MS. The expression of proteins that were significantly different and had a fold difference of at least 2 had been identified and then validated using Western blot. Our study demonstrated apolipoprotein A-I (APOA-I), serum amyloid A (SAA), transferrin (TF), haptoglobin (HP) and transthyretin (TTR) have significantly different expression between mild and severe leptospirosis. The Ingenuity Pathway Analysis software suggested the expression of these five proteins were modulated by acute phase response signaling pathway. Besides that, a functional network of lipid metabolism, molecular transport and small molecule biochemistry that interconnects these five proteins with interactomes also had been predicted by this software. In conclusion, this finding supports the potential of these five proteins to be the biomarkers for mild and severe human leptospirosis.
  4. Jamaludin TSS, Nurumal MS, Ahmad N, Muhammad SAN, Chan CM
    Enferm Clin, 2021 04;31 Suppl 2:S58-S62.
    PMID: 33849230 DOI: 10.1016/j.enfcli.2020.10.019
    This systematic review aimed to appraise and synthesize the available evidence that examines the soft skill elements in clinical nursing assessment for undergraduate nursing students. This systematic review also is in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant studies were identified based on the inclusion criteria with language filters but were limited to articles published from January 2000 to March 2019. Two reviewers independently conducted the quality assessment, data extraction, and analysis on all included studies. A total of 17 articles were included in this review. Studies showed that without developing adequate soft skill elements in the clinical skill assessment, students are graduating unprepared to be successful in the workplace. There is a need to consider and adopt soft skill elements in clinical skill assessment to improve the quality of nursing graduates and ultimately to create a positive impact on patient outcomes.
  5. Ghobadi Y, Pradhan B, Shafri HZ, bin Ahmad N, Kabiri K
    Environ Monit Assess, 2015 Jan;187(1):4156.
    PMID: 25421858 DOI: 10.1007/s10661-014-4156-0
    Wetlands are regarded as one of the most important ecosystems on Earth due to various ecosystem services provided by them such as habitats for biodiversity, water purification, sequestration, and flood attenuation. The Al Hawizeh wetland in the Iran-Iraq border was selected as a study area to evaluate the changes. Maximum likelihood classification was used on the remote sensing data acquired during the period of 1985 to 2013. In this paper, five types of land use/land cover (LULC) were identified and mapped and accuracy assessment was performed. The overall accuracy and kappa coefficient for years 1985, 1998, 2002, and 2013 were 93% and 0.9, 92% and 0.89, 91% and 0.9, and 92% and 0.9, respectively. The classified images were examined with post-classification comparison (PCC) algorithm, and the LULC alterations were assessed. The results of the PCC analysis revealed that there is a drastic change in the area and size of the studied region during the period of investigation. The wetland lost ~73% of its surface area from 1985 to 2002. Meanwhile, post-2002, the wetland underwent a restoration, as a result of which, the area increased slightly and experienced an ~29% growth. Moreover, a large change was noticed at the same period in the wetland that altered ~62% into bare soil in 2002. The areal coverage of wetland of 3386 km(2) in 1985 was reduced to 925 km(2) by 2002 and restored to 1906 km(2) by the year 2013. Human activities particularly engineering projects were identified as the main reason behind the wetland degradation and LULC alterations. And, lastly, in this study, some mitigation measures and recommendations regarding the reclamation of the wetland are discussed. Based on these mitigate measures, the discharge to the wetland must be kept according to the water requirement of the wetland. Moreover, some anthropogenic activities have to be stopped in and around the wetland to protect the ecology of the wetland.
  6. Arsad FS, Hod R, Ahmad N, Baharom M, Ja'afar MH
    Environ Sci Pollut Res Int, 2023 Jun;30(29):73137-73149.
    PMID: 37211568 DOI: 10.1007/s11356-023-27089-9
    Thermal comfort is linked to our health, well-being, and productivity. The thermal environment is one of the main factors that influence thermal comfort and, consequently, the productivity of occupants inside buildings. Meanwhile, behavioural adaptation is well known to be the most critical contributor to the adaptive thermal comfort model. This systematic review aims to provide evidence regarding indoor thermal comfort temperature and related behavioural adaptation. Studies published between 2010 and 2022 examining indoor thermal comfort temperature and behavioural adaptations were considered. In this review, the indoor thermal comfort temperature ranges from 15.0 to 33.8 °C. The thermal comfort temperature range varied depending on several factors, such as climatic features, ventilation mode, type of buildings, and age of the study population. Elderly and younger children have distinctive thermal acceptability. Clothing adjustment, fan usage, AC usage, and open window were the most common adaptive behaviour performed. Evidence shows that behavioural adaptations were also influenced by climatic features, ventilation mode, type of buildings, and age of the study population. Building designs should incorporate all factors that affect the thermal comfort of the occupants. Awareness of practical behavioural adaptations is crucial to ensure occupants' optimal thermal comfort.
  7. Vejan P, Abdullah R, Ahmad N, Khadiran T
    Environ Sci Pollut Res Int, 2023 Mar;30(13):38738-38750.
    PMID: 36585594 DOI: 10.1007/s11356-022-24970-x
    The oil palm kernel shell biochar (OPKS-B) and oil palm kernel shell activated carbon (OPKS-AC) were used as a framework to entrap urea using adsorption method. Batch adsorption studies were performed to gauge the influence of contact time on the adsorption of urea onto both OPKS-B and OPKS-AC. To evaluate the physicochemical traits of the studied materials, energy dispersive X-ray spectrometer (EDS), N2-sorption, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), elemental analysis, differential thermal gravity (TG/DTG) and thermal gravity were applied. Result shows OPKS-AC has a better sorption capacity for urea compared to OPKS-B. The Langmuir isotherm model better justified the sorption isotherms of urea. For the adsorption process for both OPKS-B and OPKS-AC, the pseudo-second-order kinetic model was picked as it best fitted the experimental sorption outcome with the superior R2 values of > 65.1% and > 74.5%, respectively. The outcome of the experiments showcased that the maximum monolayer adsorption capacity of the OPKS-AC towards urea was 239.68 mg/g. OPKS-AC has showed promising attributes to be picked as an organic framework in the production of controlled release urea fertiliser for a greener and environmentally friendly agricultural practices.
  8. Khan HHA, Ahmad N, Yusof NM, Chowdhury MAM
    Environ Sci Pollut Res Int, 2024 Feb;31(6):9784-9794.
    PMID: 38194178 DOI: 10.1007/s11356-023-31809-6
    This study critically examines the dynamic interplay between green finance and environmental sustainability using a systematic review and bibliometric analysis. The analysis is centered on 507 scholarly articles published between 2013 and 2023 in the Scopus database and leverages Microsoft Excel, Harzing Publish or Perish, and VOSviewer to identify publication trends, key contributors, research impact, and emergent themes in this rapidly evolving field. The findings reveal that research on green finance and environmental sustainability has increased exponentially over the past decade, with China and institutions in Asia emerging as prominent contributors compared to other regions. This study also identified the Environmental Science and Pollution Research journal as the most active source title, demonstrating its commitment to publishing current findings on the topic. Through keyword analysis, several research avenues have been proposed to guide future research on enhancing the strategic role of green finance in promoting environmental sustainability. These avenues include broadening the geographical scope of research, exploring the synergies between green finance and emerging fintech innovations, developing robust metrics to quantify the socioeconomic impacts of green finance, establishing a risk and resilience framework to protect green finance against uncertainties, and creating a Green Finance Performance Index to evaluate the dual returns of environmental and financial performance.
  9. Amin M, Yousuf M, Attaullah M, Ahmad N, Azra MN, Lateef M, et al.
    Environ Technol, 2023 Jun;44(14):2148-2156.
    PMID: 34962184 DOI: 10.1080/09593330.2021.2024276
    Organophosphates (OPs) and synthetic pyrethroids (SPs) are the most popular broad spectrum pesticides, used in agriculture as they have a strong pesticidal activity while also being biodegradable in the environment. The present study aimed to demonstrate the effects of these pesticides on the Acetylcholinesterase (AChE) activity in brain, gills and body muscles of Oreochromis niloticus - an important enzyme for the assessment and biomonitoring pollution caused by neurotoxins in the environment. The fish were exposed for 24 and 48 h to the LC0 concentrations of the malathion (1.425 mg/L), the chlorpyrifos (0.125 mg/L) and the λ-cyhalothrin (0.0039 mg/L), respectively. The activity of the AChE was significantly increased (p 
  10. Husain S, Ramos JA, Karaf JHA, Zahedi FD, Ahmad N, Abdullah B
    Eur Arch Otorhinolaryngol, 2023 Feb;280(2):737-741.
    PMID: 35900386 DOI: 10.1007/s00405-022-07563-9
    PURPOSE: To evaluate the efficacy of topical tranexamic acid (TXA) in reducing intraoperative and immediate postoperative bleeding during functional endoscopic sinus surgery (FESS) among patients with chronic rhinosinusitis with nasal polyposis (CRSwNP).

    METHODS: This is a double-blind randomized clinical trial, involving 26 patients with CRSwNP, who underwent FESS for failed medical therapy. The intervention nostril was packed with ribbon gauze soaked in 500 mg/5 ml TXA. The control nostril was packed with ribbon gauze soaked in Moffett's solution, containing 2 ml 10% cocaine, 1 ml adrenaline 1:1000, and 4 ml 0.9% sodium bicarbonate. Both nostrils were packed for 15 min before FESS. Intraoperative bleeding was recorded in the initial 30 min after commencing the surgery. The recordings were reviewed by two surgeons using Boezaart's scoring system. The scores were taken at 15 and 30 min of surgery. The mean score was then calculated. At the end of the surgery, the intervention nostril was packed with Merocel® soaked in 500 mg/5 ml TXA and the control nostril was packed with Merocel® soaked in normal saline. The amount of bleeding within 24 h post-surgery was evaluated using a bolster gauze.

    RESULTS: There was no significant difference in intraoperative bleeding between the intervention (1.54 ± 0.71) and control nostrils (1.69 ± 0.55) with p = 0.172. The amount of bleeding in the postoperative period was significantly reduced in the intervention nostril (1.33 ± 0.55) compared to the control nostril saline (1.81 ± 0.48) with p = 0.001.

    CONCLUSIONS: We found that the nasal packing soaked in TXA reduced intraoperative and immediate postoperative bleeding. It is a safe, efficacious and cost-effective alternative to Moffett's solution during FESS and also an alternative to normal saline post-surgery among patients with CRSwNP.

    TRIAL REGISTRATION NUMBER: FF-2015-232, 2015.

  11. Hii SYF, Zaiful Bahrina NN, Mohd Zaidi MN, Hashim R, Ahmad N
    Eur J Clin Microbiol Infect Dis, 2024 Feb;43(2):373-378.
    PMID: 37999783 DOI: 10.1007/s10096-023-04707-5
    Burkholderia pseudomallei is intrinsically resistant to many antibiotics. This study aimed to assess bacterial colony morphotypes and the validity of using disk diffusion method (DD) to determine antibiotic resistance in Malaysian clinical B. pseudomallei isolates for ceftazidime (CAZ), meropenem (MEM), amoxicillin-clavulanate (AMC) and doxycycline (DOX). DD produced good categorical agreements exhibiting concordance of 100% with reference method, broth microdilution for CAZ and DOX, 98.6% for MEM and 97.2% for AMC. Smooth-centred colonies were most frequently observed. EUCAST DD interpretative criterion is suitable to interpret B. pseudomallei CAZ, MEM, AMC and DOX resistance. Increasing AMC MIC in B. pseudomallei is a concern.
  12. Abu Kasim NH, Abu Kassim NL, Razak AA, Abdullah H, Bindal P, Che' Abdul Aziz ZA, et al.
    Eur J Dent Educ, 2014 Feb;18(1):51-7.
    PMID: 24423176 DOI: 10.1111/eje.12058
    Training dentists today is challenging as they are expected to provide a wide range of dental care. In the provision of good dental care, soft skills are equally important as clinical skills. Therefore in dental education the development of soft skills are of prime concern. This study sought to identify the development of soft skills when dental students are paired in their clinical training. In this perception study, four open-ended items were used to elicit students' feedback on the appropriateness of using clinical pairing as an instructional strategy to promote soft skills. The most frequently cited soft skills were teamwork (70%) and communication (25%) skills. However, both negative and positive behaviours were reported. As for critical thinking and problem solving skills, more positive behaviours were reported for abilities such as to explain, analyze, find ideas and alternative solutions, and make decisions. Leadership among peers was not evident as leading without legitimate authority could be a hindrance to its development. If clinical pairing is to be used as an effective instructional strategy to promote soft skills amongst students, clear guidelines need to be developed to prepare students to work in a dental team and the use of appropriate assessment tools can facilitate the development of these soft skills.
  13. Shoaib LA, Safii SH, Naimie Z, Ahmad NA, Sukumaran P, Yunus RM
    Eur J Dent Educ, 2018 Feb;22(1):e26-e34.
    PMID: 27995730 DOI: 10.1111/eje.12252
    OBJECTIVES: This study was conducted in University of Malaya to evaluate student perceptions on the contribution and role of an effective clinical teacher based on the cognitive apprenticeship model in clinical practice.

    METHODS: Self-administered questionnaires were distributed to 233 undergraduate dental students involved with clinical teaching. This modified and validated questionnaire focusing on students' learning environment was used in order to gain relevant information related to dental clinical teaching. Six domains with different criteria applicable to clinical teaching in dentistry were selected consisting of modelling (four criteria), coaching (four criteria), scaffolding (four criteria), articulation (four criteria), reflection (two criteria) and general learning environment (six criteria). Data analyses were performed using IBM SPSS Statistics 20.

    RESULTS: Majority of the students expressed positive perceptions on their clinical learning experience towards the clinical teachers in the Faculty of Dentistry, University of Malaya, in all criteria of the domains. Few negative feedbacks concerning the general learning environment were reported.

    CONCLUSION: Further improvement in the delivery of clinical teaching preferably by using wide variety of teaching-learning activities can be taken into account through students' feedback on their learning experience.

  14. Najoom S, Fozia F, Ahmad I, Wahab A, Ahmad N, Ullah R, et al.
    PMID: 34484393 DOI: 10.1155/2021/5586740
    In the present study, zinc oxide (ZnO) nanoparticles were prepared using ZnCl2.2H2O as a precursor, via green route using leaf extract of Rhazya stricta as capping and reducing agent. The prepared ZnO nanoparticles were examined using UV-visible spectrophotometer (UV-Vis), Fourier transform infrared spectrometer (FT-IR), X-ray diffraction spectrometer (XRD), and scanning electron microscope (SEM). The UV-Vis absorption spectrum at 355 nm showed an absorption peak, which indicates the formation of ZnO NPs. The FT-IR spectra analysis was performed to identify the potential biomolecule of the as-prepared ZnO NPs. The FT-IR spectra showed peaks at 3455, 1438, 883, and 671 cm-1 in the region of 4000-500 cm-1, which indicates -OH, NH, C-H, and M-O groups, respectively. The SEM images showed aggregation of ZnO nanoparticles with an average size of 70-90 nm. The XRD study indicated that the ZnO NPs were crystalline in nature with hexagonal wurtzite structure and broad peaks were observed at 2 theta positions 31.8°, 34.44°, 36.29°, 47.57°, 56.61°, 67.96°, and 69.07°. The synthesized ZnO NPs were found to be good antiplasmodial with a 50% inhibitory concentration (IC50) value of 3.41 μg/mL. It is concluded from the current study that the ZnO NPs exhibited noble antiplasmodial activity, and for the improvement of antiplasmodial medications, it might be used after further in vivo studies.
  15. Salleh NH, Zulkipli IN, Mohd Yasin H, Ja'afar F, Ahmad N, Wan Ahmad WAN, et al.
    PMID: 34691218 DOI: 10.1155/2021/5570939
    Traditionally, there are some medicinal plants believed to treat diabetes, as they have been proven in research studies to possess antidiabetic properties, such as improved insulin sensitivity and hypoglycemic activities, due to their high level of phenolic compounds, flavonoids, terpenoids, alkaloids, and glycosides. We conducted a systematic review to identify potential medicinal plants used during human clinical trials in the Association of Southeast Asian Nation (ASEAN) countries on prediabetic or type 2 diabetic individuals and to potentially identify any bioactive compounds involved in effectively treating symptoms of diabetes such as lowering of blood glucose. A total of 1209 reference titles were retrieved from four selected databases (Science Direct, Scopus, Springer Link, and PubMed) and only three met the inclusion criteria. Upon evaluation of the selected articles, four medicinal plants were identified: turmeric (Curcuma longa), garlic (Allium sativum L.), bitter melon (Momordica charantia), and Rosella flower (Hibiscus sabdariffa L.). Of these, only the bitter melon study did not show any significant change in the blood glucose of participants after intervention. This review demonstrates the limitations in published articles of human clinical trials for medicinal plants' intervention for diabetes. Upon further investigations on the four identified medicinal plants included in the animal studies, the findings showed positive effects in the management of diabetes, such as hyperglycemia. Hence, further testing and standardization of the methods in the studies can be suggested for human clinical trials for reliable data collections such as methods of extract preparation, duration of intervention, and conditions set for the study design.
  16. Ord TJ, Diesmos A, Ahmad N, Das I
    Evolution, 2023 Mar 01;77(3):660-669.
    PMID: 36626820 DOI: 10.1093/evolut/qpac057
    We identified hypotheses for the cause and consequences of the loss of complexity in animal signals and tested these using a genus of visually communicating lizards, the Southeast Asian Draco lizards. Males of some species have lost the headbob component from their display, which is otherwise central to the communication of this genus. These males instead display a large, colorful dewlap to defend territories and attract mates. This dewlap initially evolved to augment the headbob component of the display, but has become the exclusive system of communication. We tested whether the loss of headbobs was caused by relaxed selection, habitat-dependent constraints, or size-specific energetic constraints on display movement. We then examined whether the consequences of this loss have been mitigated by increased signaling effort or complexity in the color of the dewlap. It appears the increased cost of display movement resulting from the evolution of large body size might have contributed to the loss of headbobs and has been somewhat compensated for by the evolution of greater complexity in dewlap color. However, this evolutionary shift is unlikely to have maintained the complexity previously present in the communication system, resulting in an apparent detrimental loss of information potential.
  17. Amin MC, Ahmad N, Pandey M, Abeer MM, Mohamad N
    Expert Opin Drug Deliv, 2015 Jul;12(7):1149-61.
    PMID: 25547588 DOI: 10.1517/17425247.2015.997707
    Supramolecular hydrogels, formed by noncovalent crosslinking of polymeric chains in water, constitute an interesting class of materials that can be developed specifically for drug delivery and biomedical applications. The biocompatibility, stimuli responsiveness to various external factors, and powerful functionalization capacity of these polymeric networks make them attractive candidates for novel advanced dosage form design.
  18. Ahmad N, Mohd Amin MC, Ismail I, Buang F
    Expert Opin Drug Deliv, 2016 May;13(5):621-32.
    PMID: 26943455 DOI: 10.1517/17425247.2016.1160889
    Oral insulin administration suffers gastrointestinal tract (GIT) degradation and inadequate absorption from the intestinal epithelium resulting in poor bioavailability. This study entails in vitro and in vivo assessment of stimuli-responsive hydrogel microparticles (MPs) in an attempt to circumvent GI barrier and enhance oral insulin bioavailability.
  19. Charles Shapu R, Ismail S, Ahmad N, Lim PY, Abubakar Njodi I
    Foods, 2020 Sep 10;9(9).
    PMID: 32927593 DOI: 10.3390/foods9091265
    Inadequate food security contributes to poor health outcome for all, including adolescent girls. The study aims at determining the level of food security and hygiene among adolescent girls. A school-based cross-sectional study was carried out among adolescent girls aged 10 to 19 years old from six schools in Maiduguri Metropolitan Council, Borno State. The instrument for data collection was a questionnaire using KoBoCollect Toolbox between June and July 2019. Multivariable logistic regression was used to identify the predictors of food security and hygiene among respondents. A majority of the respondents (73.5%) were in a very low food security level. Three factors were significantly associated with food security level, these included schools (p = 0.007), age of mother (p = 0.004), and occupation of mother (p < 0.001). School (p = 0.003), age (father p = 0.017; mother; p = 0.012), hygiene (p = 0.005), and occupation of mother (p = 0.002) were predictors of food security. About (46.6%) of respondents had poor hygiene practice, school (p = 0.016) was significantly associated with hygiene practice. School (p = 0.019; and p = 0.005) and food security (p = 0.009) were predictors of hygiene practice. This study reveals a high prevalence of low food security among adolescent girls.
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