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Psychotropic medication in depression

Woon TH

Family Practitioner, 1973;1(1):13-16.

Matched MeSH terms: Depression
Postnatal depression and its associated factors in women from different cultures

Abdollahi F, Lye MS, Md Zain A, Shariff Ghazali S, Zarghami M

Iran J Psychiatry Behav Sci, 2011;5(2):5-11.
PMID: 24644441

OBJECTIVE: Postpartum depression (PPD) is a common health problem which affects women in the postpartum period. This is a brief note on its associated factors in women from different cultures.
METHODS: A literature review was performed in MEDLINE and Pubmed from 1991 to 2008 and Magiran from 1991 to 2009. Additional articles and book chapters were referenced from these sources.
RESULTS: The prevalence of postpartum depression has been reported to be from 0.5% to 60% globally, and from 3.5% to 63.3% in Asian countries, in which Malaysia and Pakistan had respectively the lowest and highest rates. One of the factors contributing to PPD in Asian societies can be that women may not have the empowerment to reject traditional rituals that are imposed on them by their caregivers. Unsatisfactory pre-existing relationships between the mothers and their caregivers resulting in mothers experiencing difficulties during their confinement period may be another factor. Thirdly, some features of these traditional rituals may be the cause of tension, stress and emotional distress. Emotional conflicts caused by insistence on practice of traditional rituals during the postpartum period may lead to mental breakdown.
CONCLUSION: Health care professionals should be aware that the phenomenon in Asian cultures is as prevalent as European cultures. Moreover, further research needs to be conducted on the global prevalence of the experiences of childbearing women with depressive symptoms.
KEYWORDS: Cultures; Postpartum depression; Risk factors

Matched MeSH terms: Depression, Postpartum*
Cross-cultural and social diversity of prevalence of postpartum depression and depressive symptoms

Halbreich U, Karkun S

J Affect Disord, 2006 Apr;91(2-3):97-111.
PMID: 16466664 DOI: 10.1016/j.jad.2005.12.051

BACKGROUND:
The prevalence of postpartum depression (PPD) is currently considered to be 10-15%. Most studies were performed with a brief unidimensional instruments (mostly the Edinburgh Postnatal Depression Scale-EPDS) with focus on depression and not on other symptoms and disorders. Most cited studies were conducted in Western economically developed countries.

METHODS:
We reviewed the literature on prevalence of postpartum depression and depressive symptoms in a wide range of countries.

RESULTS:
143 studies were identified reporting prevalence in 40 countries. It is demonstrated that there is a wide range of reported prevalence of PPD ranging from almost 0% to almost 60%. In some countries like Singapore, Malta, Malaysia, Austria and Denmark there are very few reports of PPD or postpartum depressive symptoms, whereas in other countries (e.g. Brazil, Guyana, Costa Rica, Italy, Chile, South Africa, Taiwan and Korea) reported postpartum depressive symptoms are very prevalent.

CONCLUSIONS:
We believe that the widely cited mean prevalence of PPD-10-15% is not representative of the actual global prevalence and magnitude of the problem, due to the wide range of reports. The variability in reported PPD might be due to cross-cultural variables, reporting style, differences in perception of mental health and its stigma, differences in socio-economic environments (e.g. poverty, levels of social support or its perception, nutrition, stress), and biological vulnerability factors. The elucidation of the underlying processes of this variability as well as the diversity of postpartum normal versus abnormal expressions of symptoms may contribute to better understanding of the diversified ante, peri- and postpartum phenomena.

Matched MeSH terms: Depression/diagnosis; Depression/epidemiology*; Depression/psychology; Depression, Postpartum/diagnosis; Depression, Postpartum/epidemiology*; Depression, Postpartum/psychology
Fulltext Emotional Intelligence and Depressive Symptoms as Predictors of Happiness Among Adolescents

Abdollahi A, Abu Talib M, Motalebi SA

Iran J Psychiatry Behav Sci, 2015 Dec;9(4):e2268.
PMID: 26834804 DOI: 10.17795/ijpbs-2268

BACKGROUND: Given that happiness is an important construct to enable adolescents to cope better with difficulties and stress of life, it is necessary to advance our knowledge about the possible etiology of happiness in adolescents.
OBJECTIVES:The present study sought to investigate the relationships of emotional intelligence, depressive symptoms, and happiness in a sample of male students in Tehran, Iran.
MATERIALS AND METHODS: This cross-sectional study was conducted on a sample of high school students in Tehran in 2012. The participants comprised of 188 male students (aged 16 to 19 years old) selected by multi-stage cluster sampling method. For gathering the data, the students filled out assessing emotions scale, Beck depression inventory-II, and Oxford happiness inventory. Data analysis was carried out using descriptive and analytical statistics in statistical package for social sciences (SPSS) software.
RESULTS: The findings showed that a significant positive association existed between high ability of emotional intelligence and happiness (P < 0.01). Conversely, the low ability of emotional intelligence was associated with unhappiness (P < 0.01), there was a positive association between non-depression symptoms and happiness (P < 0.05), and severe depressive symptoms were positively associated with unhappiness (P < 0.01). High ability of emotional intelligence (P < 0.01) and non-depression symptoms (P < 0.05) were the strongest predictors of happiness.
CONCLUSIONS: These findings reinforced the importance of emotional intelligence as a facilitating factor for happiness in adolescences. In addition, the findings suggested that depression symptoms may be harmful for happiness in adolescents.

KEYWORDS:
Depression; Emotional Intelligence; Iranian Students; Wellbeing

Matched MeSH terms: Depression*
Fulltext Prediction of incidence and bio-psycho-socio-cultural risk factors of post-partum depression immediately after birth in an Iranian population

Abdollahi F, Zarghami M, Sazlina SG, Zain AM, Mohammad AJ, Lye MS

Arch Med Sci, 2016 Oct 1;12(5):1043-1051.
PMID: 27695496

INTRODUCTION: Post-partum depression (PPD) is the most prevalent mental problem associated with childbirth. The purpose of the present study was to determine the incidence of early PPD and possible relevant risk factors among women attending primary health centers in Mazandaran province, Iran for the first time.
MATERIAL AND METHODS: A longitudinal cohort study was conducted among 2279 eligible women during weeks 32-42 of pregnancy to determine bio-psycho-socio-cultural risk factors of depression at 2 weeks post-partum using the Iranian version of the Edinburgh Postnatal Depression Scale (EPDS). Univariate and hierarchical multiple logistic regression models were used for data analysis.
RESULTS: Among 1,739 mothers whose EPDS scores were ≤ 12 during weeks 32-42 of gestation and at the follow-up study, the cumulative incidence rate of depression was 6.9% (120/1,739) at 2 weeks post-partum. In the multivariate model the factor that predicted depression symptomatology at 2 weeks post-partum was having psychiatric distress in pregnancy based on the General Health Questionnaire (GHQ) (OR = 1.06, (95% CI: 1.04-1.09), p = 0.001). The risk of PPD also lower in those with sufficient parenting skills (OR = 0.78 (95% CI: 0.69-0.88), p = 0.001), increased marital satisfaction (OR = 0.94 (95% CI: 0.9-0.99), p = 0.03), increased frequency of practicing rituals (OR = 0.94 (95% CI: 0.89-0.99), p = 0.004) and in those whose husbands had better education (OR = 0.03 (95% CI: 0.88-0.99), p = 0.04).
CONCLUSIONS: The findings indicated that a combination of demographic, sociological, psychological and cultural risk factors can make mothers vulnerable to PPD.
KEYWORDS: depression; incidence; post-partum

Matched MeSH terms: Depression, Postpartum*
The relationship between post-natal depression, somatization and behaviour in Malaysian women

Grace J, Lee KK, Ballard C, Herbert M

Transcult Psychiatry, 2001;38:27-34.
DOI: 10.1177/136346150103800103

This study evaluated the rate of post-natal depression (PND) in a Malaysian population, investigated the relationship between belief systems and PND, and examined the relationship between PND and somatization. The sample included 154 consecutive attendees for a 6-week post-natal check at a general hospital well-baby clinic in Kuala Lumpur. Patients were assessed using the Edinburgh Post-Natal Depression Score (EPNDS), the Bradford Somatisation Inventory (BSI), and a questionnaire to assess beliefs about pregnancy and childbirth. The rate of PND was 3.9%. EPNDS and BSI were moderately correlated. Women who practised specific post-natal practices had a higher EPNDS and BSI than those who did not. The rate of PND is lower than in Western studies but similar to that seen in other Asian countries. The correlation between BSI and EPNDS suggest that the BSI will not detect cases missed by the EPNDS. © 2001, Sage Publications. All rights reserved.

Matched MeSH terms: Depression; Depression, Postpartum
Fulltext A survey on burnout and depression risk among anaesthetists during COVID-19: the tip of an iceberg?

Tsan SEH, Kamalanathan A, Lee CK, Zakaria SA, Wang CY

Anaesthesia, 2021 03;76 Suppl 3:8-10.
PMID: 32776524 DOI: 10.1111/anae.15231
Matched MeSH terms: Depression/epidemiology
Fulltext Interpersonal psychotherapy for depression in the ageing – A case study. [Abstract]

Pereira XV

Malaysian Journal of Medicine and Health Sciences, 2019;15(102):30.
MyJurnal

ABSTRACTS FOR INTERNATIONAL HEALTH AND MEDICAL SCIENCES CONFERENCE 2019
IHMSC 2019. Accelerating Innovations in Translational and Precision Medicine. Held at Taylor’s University Lakeside Campus, Subang Jaya, Selangor, Malaysia, 8-9th March, 2019
Introduction: Depression is becoming increasingly prevalent as a mental health disorder worldwide. The prevalence of clinical depression is between about five and fifteen percent globally. Clinical depression has also increased in prevalence among the ageing. Some of the etiological factors associated with depression in the ageing include grief and loss, and role transitions. Interpersonal Psychotherapy (IPT), an evidenced based psychotherapy for clinical depression, has been proven to be effective for depression in the ageing. IPT addresses four main problem areas, namely - interpersonal disputes, grief and loss, role transitions and interpersonal sensitivity. The adaptation of IPT for the ageing is IPT for late-life depression or IPT – LLM which was utilized to treat the patient discussed in this case study. Methods: The patient was treated with 12 sessions of psychotherapy which is often the minimum number of sessions required in the treatment of depression with IPT. The initial sessions included the development of an Interpersonal Formulation and Interpersonal Inventory. Her problem areas were grief as her husband had passed away recently, and role transitions. The problem areas were addressed during the 8 middle IPT sessions. The final two sessions were utilized to conclude IPT treatment. Results: The patient was assessed to have a PHQ – 9 (Patient Health Questionnaire--9) score of 17 before treatment with IPT, indicating moderate depression. Her PHQ – 9 score after 12 sessions of IPT was 4 indicating minimal depression. Conclusion: This case study highlights that some of the factors that contribute to depression in the ageing are grief and role transitions, and that IPT is efficacious in the treatment of depression in the ageing.

Matched MeSH terms: Depression*
Depression Following Major Life Transitions in Women: A Review and Theory

Moustafa AA, Crouse JJ, Herzallah MM, Salama M, Mohamed W, Misiak B, et al.

Psychol Rep, 2020 Oct;123(5):1501-1517.
PMID: 31470771 DOI: 10.1177/0033294119872209

Depression can occur due to common major life transitions, such as giving birth, menopause, retirement, empty-nest transition, and midlife crisis. Although some of these transitions are perceived as positive (e.g., giving birth), they may still lead to depression. We conducted a systematic literature review of the factors underlying the occurrence of depression following major life transition in some individuals. This review shows that major common life transitions can cause depression if they are sudden, major, and lead to loss (or change) of life roles (e.g., no longer doing motherly or fatherly chores after children leave family home). Accordingly, we provide a theoretical framework that explains depression caused by transitions in women. One of the most potential therapeutic methods of ameliorating depression associated with life transitions is either helping individuals accept their new roles (e.g., accepting new role as a mother to ameliorate postpartum depression symptoms) or providing them with novel life roles (e.g., volunteering after retirement or children leave family home) may help them overcome their illness.

Matched MeSH terms: Depression/etiology*; Depression/epidemiology*; Depression/psychology; Depression, Postpartum/etiology; Depression, Postpartum/epidemiology; Depression, Postpartum/psychology
State of the Science on postpartum depression: what nurse researchers have contributed--part 1

Beck CT

MCN Am J Matern Child Nurs, 2008 Mar-Apr;33(2):121-6.
PMID: 18327112 DOI: 10.1097/01.NMC.0000313421.97236.cf

Postpartum depression has been described as a thief that steals motherhood. It can result in tragedy and sometimes in headline-gripping maternal suicide or infanticide. Because one of the highest priorities for nursing is to continually advance the knowledge that underlies nursing practice, it is essential that we understand what nurse researchers have done to advance the knowledge base of postpartum depression. This integrative review is a two-part series for MCN that summarizes 141 postpartum depression studies conducted by nurse researchers from around the globe, including United States, Australia, Canada, China (Hong Kong, Taiwan), Finland, Iceland, Sweden, Turkey, and Malaysia. Specific areas of postpartum depression to which nurse researchers have devoted their primary attention include epidemiology, risk factors, transcultural perspectives, instrument development, screening, interventions, and mother-infant interactions.

Matched MeSH terms: Depression, Postpartum/ethnology; Depression, Postpartum/nursing; Depression, Postpartum/prevention & control*; Depression, Postpartum/psychology
Fulltext Managing depression in primary care

Ng CW, How CH, Ng YP

Singapore Med J, 2017 08;58(8):459-466.
PMID: 28848991 DOI: 10.11622/smedj.2017080

Major depression is common in the primary care setting. In the final article of this series, we illustrate the approach to the management of depression in primary care. Psychotherapy has been shown to be as effective as antidepressants for mild to moderate major depression. The common myth that antidepressants are addictive should be addressed. Antidepressants should be started at a subtherapeutic dose to assess tolerability, then gradually increased until a minimally effective dose is achieved. Apart from pharmacotherapy and psychotherapy, management of depression should include managing stressors, engaging social and community support, dealing with stigma and discrimination, and managing concomitant comorbidities. A strong therapeutic relationship and empathic listening are important between the primary care physician and patient.

Matched MeSH terms: Depression/drug therapy; Depression/therapy*
Depression and Severity of Glaucoma Among Older Adults in Urban and Suburban Areas

Tharmathurai S, Muhammad-Ikmal MK, Razak AA, Che-Hamzah J, Azhany Y, Fazilawati Q, et al.

J Glaucoma, 2021 05 01;30(5):e205-e212.
PMID: 33710066 DOI: 10.1097/IJG.0000000000001830

PRCIS: Depression increases with severity of visual field defect in older adults with primary open-angle glaucoma (POAG).
PURPOSE: This study aimed to determine the prevalence of depression among patients with POAG and examine the relationship between depression and the severity of POAG in older adults.
MATERIALS AND METHODS: Three hundred and sixty patients with POAG aged 60 years or above were recruited from 2 tertiary centers located in an urban and suburban area. The participants were stratified according to the severity of their glaucoma based on the scores from the modified Advanced Glaucoma Intervention Study (AGIS) to mild, moderate, severe, and end stage. Face-to-face interviews were performed using the Malay Version Geriatric Depression Scale 14 (mGDS-14) questionnaire. Depression is diagnosed when the score is ≥8. One-way analysis of variance was used to compare the subscores between the groups. Multifactorial analysis of variance was also applied with relevant confounding factors.
RESULTS: Depression was detected in 16% of older adults with POAG; a higher percentage of depression was seen in those with end stage disease. There was a significant increase in the mean score of mGDS-14 according to the severity of POAG. There was evidence of an association between depression and severity of visual field defect (P<0.001). There was a significant difference in mGDS-14 score between the pairing of severity of POAG [mild-severe (P=0.003), mild-end stage (P<0.001), moderate-severe (P<0.001), and moderate-end stage (P<0.001)] after adjustment to living conditions, systemic disease, and visual acuity.
CONCLUSION: Ophthalmologists should be aware that older adults with advanced visual field defects in POAG may have depression. The detection of depression is important to ensure adherence and persistence to the treatment of glaucoma.

Matched MeSH terms: Depression/diagnosis; Depression/epidemiology
Clinical and economic impact of non-adherence to antidepressants in major depressive disorder: A systematic review

Ho SC, Chong HY, Chaiyakunapruk N, Tangiisuran B, Jacob SA

J Affect Disord, 2016 Mar 15;193:1-10.
PMID: 26748881 DOI: 10.1016/j.jad.2015.12.029

Medication non-adherence is one of the major challenges in treating patients with depression. This systematic review aims to determine the clinical and economic outcomes of non-adherence in depression.

Matched MeSH terms: Depression
Fulltext Association between subclinical hypothyroidism and depression: an updated systematic review and meta-analysis

Loh HH, Lim LL, Yee A, Loh HS

BMC Psychiatry, 2019 01 08;19(1):12.
PMID: 30621645 DOI: 10.1186/s12888-018-2006-2

BACKGROUND: Although depression is associated with changes in the hypothalamic-pituitary-thyroid axis, its relationship with subclinical hypothyroidism (SCH) is controversial. To date, there is a lack of data on the improvement of depressive symptoms with levothyroxine therapy among individuals with coexistent SCH.
METHODS: We conducted a meta-analysis to evaluate the association between SCH and depression including 1) the prevalence of depression in SCH (with a sub-analysis of the geriatric cohort), 2) thyroid stimulating hormone (TSH) level among patients with depression and 3) the effect of levothyroxine therapy among patients with SCH and coexistent depression.
RESULTS: In a pooled analysis of 12,315 individuals, those with SCH had higher risk of depression than euthyroid controls (relative risk 2.35, 95% confidence intervals [CI], 1.84 to 3.02; p

Matched MeSH terms: Depression/diagnosis; Depression/epidemiology*; Depression/psychology*
Screening for depression

Wong YC

Family Practitioner, 1981;4<I> </I>:27-30.

Matched MeSH terms: Depression
Tropical neurasthenia

Lamprell BA

Med J Malaya, 1948;3:34-40.

The author during a long tropical service has seen a distressing number of cases of tropical neurasthenia including a number that ended in suicide. The condition is common in Malaya of which he is writing. In a group of rubber plantations with an average staff of 75 (presumably Europeans) in the past two years, one has committed suicide, eight have been repatriated for nervous breakdown, and two have been sent on home leave for the same reason. In a series of 33 invalidings analysed by SQUIRES [no reference given] 45 per cent. [15] were for psychological reasons. Neurasthenia in the tropics differs from that seen in practice in temperate countries by the predominance of cerebral over spinal symptoms. The mild cases show increased irritability with occasional outbursts of uncon rolled rages, restlessness, and moderate amnesia. In the intermediate cases these symptoms are worse and periods of worry and depression occur, often amounting to delusions of persecution with insomnia. In the severe cases, the depression is predominant; to this is added procrastination and indecision, loss of confidence, fear of insanity and of loss of employment, which constitute a vicious cycle that may end in suicide. The author classes the causes as personal and environmental, the former being the more important; the prominence of the personal factor is due to the tendency for social misfits and others who are dissatisfied with home conditions to seek employment in the tropics where they hope to find life easier. The environmental factors are (i) Exile from one's own country and loss of firm roots in a place that one calls home, (ii) The excessive stimuli of the tropics; under this heading the author includes the direct effects of the climate and discusses the sexual factor, (iii) Overwork and excessive responsibility, (iv) Isolation and monotony; under this last heading [the sequence of thought is obscure to the reviewer] he includes a suggestion that the recent increased rate of breakdown in Malaya may be due to years of war strain and present economic and political difficulties. The preventive measures he advocates include more careful selection of candidates for service in the tropics and the suggestion that a psychiatric assessment as well as a physical examination should be made; more frequent home leave; annual local leave to a hill station; shorter office hours; more security of tenure of appointments in commercial undertakings; and freedom to marry early in his service. Finally, the author suggests that, since this problem is an admittedly serious one, the Malayan branch of the British Medical Association should make a study of its aetiology and prevention, and convey their conclusions to the Government and to commercial and industrial associations. L. E. Napier.

Matched MeSH terms: Depression
Commentary: Tractography-Guided Anterior Capsulotomy for Major Depression and Obsessive-Compulsive Disorder: Targeting the Emotion Network

Idris Z, Zakaria Z, Fitzrol DN, Ang SY, Yee SV, Ghani ARI, et al.

Oper Neurosurg (Hagerstown), 2021 03 15;20(4):E281-E283.
PMID: 33475706 DOI: 10.1093/ons/opaa473
Matched MeSH terms: Depression
Fulltext Analysis of the Psychometric Properties of the Malay Version of Beck Depression Inventory II (BDI-II) Among Postpartum Women in Kedah, North West of Peninsular Malaysia

Wan Mahmud WM, Awang A, Herman I, Mohamed MN

Malays J Med Sci, 2004 Jul;11(2):19-25.
PMID: 22973123

Increased international collaboration in clinical trials has created a need for cross culturally valid instruments to assess the quality of life and behavioural disorders. Cross cultural studies of depressive symptomatology, in particular, must be preceded by an exhaustive study of the psychometric properties of the instruments to ensure the validity of the comparison. In this article, we examined the validity, reliability and factor structure of the Malay version of the Beck Depression Inventory II (BDI-II) among Malay postpartum women attending selected health centres in Kedah, North West of Peninsular Malaysia. Our findings indicated that the current version of the BDI-II is psychometrically strong and appropriate for use in assessing depressive symptomatology among this group of women.

Matched MeSH terms: Depression*
The effectiveness of gamelan therapy on depression levels in chronic kidney failure patients

Nurhidayati T, Pambudi DA, Rahayu DA, Elengoe A, Ramuni K

Enferm Clin, 2020 06;30 Suppl 5:69-72.
PMID: 32713588 DOI: 10.1016/j.enfcli.2019.11.023

INTRODUCTION: The effect of depression on human behavior have been widely recognized in chronic kidney failure patients who undergoing hemodialysis. There was some depression technique management which could be applied. It could be a pharmacological or non-pharmacological technique. One of the complementary non-pharmacological therapy are Javanese gamelan therapy.
OBJECTIVE: This research reduced depression level with Javanese gamelan therapy in chronic kidney failure patients' who undergo hemodialysis at RSUD KRMT Wongsonegoro Semarang.
METHOD: It was a quasi-experimental research with pretest-post-test without control group. The research was administered during March-May 2019 with 30 respondents taken as sample using the total sampling technique.
RESULTS: The research on 30 respondents showed that p-value=0.00,

Matched MeSH terms: Depression/therapy
Appropriate cultural management as a technique to address early adolescent alcohol exposure

Pizzini N

Pediatr Int, 2020 02;62(2):251.
PMID: 32104989 DOI: 10.1111/ped.14090
Matched MeSH terms: Depression*

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