Displaying publications 1 - 20 of 209 in total

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  1. Fulltext Wellen's syndrome: Challenges in diagnosis
    Agarwal A, Vyas S, Kumar R
    Malays Fam Physician, 2015;10(3):35-7.
    PMID: 27570607
    Wellen's syndrome is a pre-infarction stage of coronary artery disease characterised by predefined clinical and electrocardiographic (ECG) criteria of a subgroup of patients with myocardial ischaemia. Early recognition and appropriate intervention of this syndrome carry significant diagnostic and prognostic value. We report this unusual syndrome in an elderly man who presented with recurrent angina and characteristic ECG changes as T-waves inversion in the precordial leads, especially in V2-V6 during pain-free periods and ECG obtained during episodes of pain demonstrating upright T-waves with possible elevated ST segments from V1-V4. Cardiac enzymes were positive and coronary angiography revealed critical stenosis in the proximal left anterior descending artery. It is important to timely identify this condition and intervene appropriately as these patients may develop extensive myocardial infarction that carries a significant morbidity and mortality.
    Matched MeSH terms: Electrocardiography
  2. Fulltext Wearable IoT Smart-Log Patch: An Edge Computing-Based Bayesian Deep Learning Network System for Multi Access Physical Monitoring System
    Manogaran G, Shakeel PM, Fouad H, Nam Y, Baskar S, Chilamkurti N, et al.
    Sensors (Basel), 2019 Jul 09;19(13).
    PMID: 31324070 DOI: 10.3390/s19133030
    According to the survey on various health centres, smart log-based multi access physical monitoring system determines the health conditions of humans and their associated problems present in their lifestyle. At present, deficiency in significant nutrients leads to deterioration of organs, which creates various health problems, particularly for infants, children, and adults. Due to the importance of a multi access physical monitoring system, children and adolescents' physical activities should be continuously monitored for eliminating difficulties in their life using a smart environment system. Nowadays, in real-time necessity on multi access physical monitoring systems, information requirements and the effective diagnosis of health condition is the challenging task in practice. In this research, wearable smart-log patch with Internet of Things (IoT) sensors has been designed and developed with multimedia technology. Further, the data computation in that smart-log patch has been analysed using edge computing on Bayesian deep learning network (EC-BDLN), which helps to infer and identify various physical data collected from the humans in an accurate manner to monitor their physical activities. Then, the efficiency of this wearable IoT system with multimedia technology is evaluated using experimental results and discussed in terms of accuracy, efficiency, mean residual error, delay, and less energy consumption. This state-of-the-art smart-log patch is considered as one of evolutionary research in health checking of multi access physical monitoring systems with multimedia technology.
    Matched MeSH terms: Electrocardiography
  3. Wavelet-based Encoding Scheme for Controlling Size of Compressed ECG Segments in Telecardiology Systems
    Al-Busaidi AM, Khriji L, Touati F, Rasid MF, Mnaouer AB
    J Med Syst, 2017 Sep 12;41(10):166.
    PMID: 28900815 DOI: 10.1007/s10916-017-0817-1
    One of the major issues in time-critical medical applications using wireless technology is the size of the payload packet, which is generally designed to be very small to improve the transmission process. Using small packets to transmit continuous ECG data is still costly. Thus, data compression is commonly used to reduce the huge amount of ECG data transmitted through telecardiology devices. In this paper, a new ECG compression scheme is introduced to ensure that the compressed ECG segments fit into the available limited payload packets, while maintaining a fixed CR to preserve the diagnostic information. The scheme automatically divides the ECG block into segments, while maintaining other compression parameters fixed. This scheme adopts discrete wavelet transform (DWT) method to decompose the ECG data, bit-field preserving (BFP) method to preserve the quality of the DWT coefficients, and a modified running-length encoding (RLE) scheme to encode the coefficients. The proposed dynamic compression scheme showed promising results with a percentage packet reduction (PR) of about 85.39% at low percentage root-mean square difference (PRD) values, less than 1%. ECG records from MIT-BIH Arrhythmia Database were used to test the proposed method. The simulation results showed promising performance that satisfies the needs of portable telecardiology systems, like the limited payload size and low power consumption.
    Matched MeSH terms: Electrocardiography*
  4. Ventricular septal defect--autopsy study of 46 cases
    Loh TF
    Med J Malaya, 1970 Jun;24(4):257-60.
    PMID: 4248345
    Matched MeSH terms: Electrocardiography
  5. Ventricular bigeminy following a cobra envenomation
    Ismail AK, Weinstein SA, Auliya M, Appareo P
    Clin Toxicol (Phila), 2012 Jul;50(6):518-21.
    PMID: 22702902 DOI: 10.3109/15563650.2012.696119
    Envenoming by some species of cobras (Naja species) may include cardiotoxic effects including various dysrhythmias. However, dysrhythmias leading specifically to ventricular bigeminy have not been previously documented. We report a case of cardiotoxicity and the development of ventricular bigeminy following a cobra envenomation.
    Matched MeSH terms: Electrocardiography
  6. Utilization of second derivative photoplethysmographic features for myocardial infarction classification
    Mahri N, Gan KB, Meswari R, Jaafar MH, Mohd Ali MA
    J Med Eng Technol, 2017 May;41(4):298-308.
    PMID: 28351231 DOI: 10.1080/03091902.2017.1299229
    Myocardial infarction (MI) is a common disease that causes morbidity and mortality. The current tools for diagnosing this disease are improving, but still have some limitations. This study utilised the second derivative of photoplethysmography (SDPPG) features to distinguish MI patients from healthy control subjects. The features include amplitude-derived SDPPG features (pulse height, ratio, jerk) and interval-derived SDPPG features (intervals and relative crest time (RCT)). We evaluated 32 MI patients at Pusat Perubatan Universiti Kebangsaan Malaysia and 32 control subjects (all ages 37-87 years). Statistical analysis revealed that the mean amplitude-derived SDPPG features were higher in MI patients than in control subjects. In contrast, the mean interval-derived SDPPG features were lower in MI patients than in the controls. The classifier model of binary logistic regression (Model 7), showed that the combination of SDPPG features that include the pulse height (d-wave), the intervals of "ab", "ad", "bc", "bd", and "be", and the RCT of "ad/aa" could be used to classify MI patients with 90.6% accuracy, 93.9% sensitivity and 87.5% specificity at a cut-off value of 0.5 compared with the single features model.
    Matched MeSH terms: Electrocardiography
  7. Fulltext Two-stage motion artefact reduction algorithm for electrocardiogram using weighted adaptive noise cancelling and recursive Hampel filter
    Ghaleb FA, Kamat MB, Salleh M, Rohani MF, Abd Razak S
    PLoS One, 2018;13(11):e0207176.
    PMID: 30457996 DOI: 10.1371/journal.pone.0207176
    The presence of motion artefacts in ECG signals can cause misleading interpretation of cardiovascular status. Recently, reducing the motion artefact from ECG signal has gained the interest of many researchers. Due to the overlapping nature of the motion artefact with the ECG signal, it is difficult to reduce motion artefact without distorting the original ECG signal. However, the application of an adaptive noise canceler has shown that it is effective in reducing motion artefacts if the appropriate noise reference that is correlated with the noise in the ECG signal is available. Unfortunately, the noise reference is not always correlated with motion artefact. Consequently, filtering with such a noise reference may lead to contaminating the ECG signal. In this paper, a two-stage filtering motion artefact reduction algorithm is proposed. In the algorithm, two methods are proposed, each of which works in one stage. The weighted adaptive noise filtering method (WAF) is proposed for the first stage. The acceleration derivative is used as motion artefact reference and the Pearson correlation coefficient between acceleration and ECG signal is used as a weighting factor. In the second stage, a recursive Hampel filter-based estimation method (RHFBE) is proposed for estimating the ECG signal segments, based on the spatial correlation of the ECG segment component that is obtained from successive ECG signals. Real-World dataset is used to evaluate the effectiveness of the proposed methods compared to the conventional adaptive filter. The results show a promising enhancement in terms of reducing motion artefacts from the ECG signals recorded by a cost-effective single lead ECG sensor during several activities of different subjects.
    Matched MeSH terms: Electrocardiography
  8. Fulltext Transient complete heart block during acute rheumatic fever: a case report
    Ong PK, Ramanathan M
    Med J Malaysia, 1987 Sep;42(3):215-6.
    PMID: 3506649
    We report a case of transient complete heart block with Stokes-Adams attack due to acute rheumatic fever. The patient was a 12-year old boy whose illness satisfied the criteria of acute rheumatic fever. A temporary transvenous cardiac pacer was necessary to tide him over the complete heart block. The rarity of this complication of acute rheumatic fever is highlighted.
    Matched MeSH terms: Electrocardiography
  9. Toxicity of the venom of the sea-snake, Laticauda colubrina, with observations on a Malay "folk cure"
    Levey HA
    Toxicon, 1969 May;6(4):269-76.
    PMID: 5805121
    Matched MeSH terms: Electrocardiography
  10. Fulltext Torsade de pointes and syncopal attacks in a 26-year old woman with congenital complete heart block and prolonged QT interval
    Quek DK, Ong SB
    Singapore Med J, 1990 Apr;31(2):185-8.
    PMID: 2371586
    A 26-year old woman with congenital complete heart block and prolonged QT interval presented for the first time with syncopal attacks associated with torsade de pointes in adulthood. Cardioversion followed by overdrive pacing was needed to finally control the unstable rhythm. During episodes of non-capture, paraoxysms of torsade de pointes leading to ventricular flutter were recorded by a 24-hour ambulatory electrocardiographic monitoring. Beta-blockade and permanent ventricular pacing finally abolished both the syncopal attacks and the torsade phenomena. The prognosis of congenital complete heart block associated with QT prolongation resembles that of the Romano-Ward syndrome. Recognition of this variant would facilitate earlier treatment of this rare but potentially lethal disorder.
    Matched MeSH terms: Electrocardiography
  11. Fulltext Torsade de pointes and sudden death associated with diabetic autonomic diarrhoea--a case report
    Quek DK, H'ng PK
    Singapore Med J, 1993 Jun;34(3):266-70.
    PMID: 8266190
    A 68-year-old diabetic and hypertensive woman presented with chronic autonomic diarrhoea, syncope and palpitations which were associated with QT prolongation and recurrent episodes of torsade de pointes. She was on glibenclamide, indapamide and probucol (for type V hyperlipidaemia). Despite intravenous infusions of potassium, lignocaine and amiodarone, the unstable rhythm persisted. However, intravenous magnesium sulphate with small doses of intravenous propranolol terminated the torsade de pointes. She was stabilised but following discharge she relapsed, and upon re-admission, succumbed to intractable ventricular fibrillation. Early recognition and aggressive treatment of this condition is emphasised. Multiple aggravating factors ie autonomic diarrhoea resulting in severe potassium and magnesium depletion, kaliuretic effect of indapamide, probable QT prolongation associated with diabetic autonomic neuropathy and probucol; probable underlying coronary artery disease and heightened emotional and sympathetic discharge could have contributed to this very unstable ventricular arrhythmia and sudden death.
    Matched MeSH terms: Electrocardiography
  12. Thyrotoxic periodic paralysis and intravenous propranolol in the emergency setting
    Birkhahn RH, Gaeta TJ, Melniker L
    J Emerg Med, 2000 Feb;18(2):199-202.
    PMID: 10699522
    A 27-year-old male of Malaysian descent presented to the Emergency Department (ED) with rapidly progressive flaccid paralysis that quickly compromised his respiratory effort. The patient was found to have a serum potassium of 1.9 meq/L, and was diagnosed as having an acute paralytic episode secondary to thyrotoxic periodic paralysis. The paralytic attack was aborted with a combination of potassium replacement and parenteral propranolol in large doses. We report the use of a rarely described, yet possibly more effective, therapy for an acute attack of thyrotoxic periodic paralysis.
    Matched MeSH terms: Electrocardiography
  13. The use of BLRP model for disaggregating daily rainfall affected by monsoon in Peninsular Malaysia
    Zulkifli Yusop, Harisaweni, Fadhilah Yusof
    Sains Malaysiana, 2016;45:87-97.
    Rainfall intensity is the main input variable in various hydrological analysis and modeling. Unfortunately, the quality of rainfall data is often poor and reliable data records are available at coarse intervals such as yearly, monthly and daily. Short interval rainfall records are scarce because of high cost and low reliability of the measurement and the monitoring systems. One way to solve this problem is by disaggregating the coarse intervals to generate the short one using the stochastic method. This paper describes the use of the Bartlett Lewis Rectangular Pulse (BLRP) model. The method was used to disaggregate 10 years of daily data for generating hourly data from 5 rainfall stations in Kelantan as representative area affected by monsoon period and 5 rainfall stations in Damansara affected by inter-monsoon period. The models were evaluated on their ability to reproduce standard and extreme rainfall model statistics derived from the historical record over disaggregation simulation results. The disaggregation of daily to hourly rainfall produced monthly and daily means and variances that closely match the historical records. However, for the disaggregation of daily to hourly rainfall, the standard deviation values are lower than the historical ones. Despite the marked differences in the standard deviation, both data series exhibit similar patterns and the model adequately preserve the trends of all the properties used in evaluating its performances.
    Matched MeSH terms: Electrocardiography
  14. Fulltext The rare congenital anomaly of scimitar syndrome: an unusual presentation in symptomatic adult
    Siti Zulaiha Binti Che Hat
    Malaysian Journal of Medicine and Health Sciences, 2020;16(3):334-336.
    MyJurnal
    Scimitar syndrome is a rare congenital heart defect occurring in 1 to 3 per 100,000 live births. This is a case of a 26 years old lady presenting with episodic fainting spells since the age of 18 years old. She was initially diagnosed with epilepsy until a referral to our centre found a soft splitting of the second heart sound and multiple premature ventricular complexes on ECG. The computed tomography of the pulmonary artery confirmed the diagnosis if Scim- itar syndrome in the presence of anomalous single right pulmonary vein draining into infra-diaphragmatic systemic venous circulation. A corrective open-heart surgery to re-implant the pulmonary vein was performed with excellent clinical outcomes. Therefore, it is crucial for clinicians to embody high index of suspicion of congenital anomaly even in adults presenting with indefinite clinical symptoms. This report also represents the first published case of adult Scimitar syndrome from Malaysia.

    Matched MeSH terms: Electrocardiography
  15. The nasocardiac reflex during nasoendoscopy: A commonly overlooked risk
    Wong A, Abu Bakar MZ
    Am J Otolaryngol, 2021 01 04;42(2):102869.
    PMID: 33429183 DOI: 10.1016/j.amjoto.2020.102869
    PURPOSE: The nasocardiac reflex is known but not well researched. We aimed to ascertain the electrocardiographic features of the reflex and to chronologically map the heart rhythm dynamics during nasoendoscopy. We also intended to identify variables that could potentially affect the occurrence of this reflex.

    MATERIAL AND METHODS: A prospective, quasi-experimental physiological study. Selected healthy subjects were observed electrocardiographically for 60 s continuously in three equal phases of 20 s each - baseline phase, nasoendoscopic phase, and recovery phase (post-nasoendoscopy). Heart rate fluctuations were charted, followed by identification of a positive nasocardiac reflex group of subjects and a negative group. Analyses against multiple variables were done.

    RESULTS: A total of 53 subjects were analysed. Heart rate during the baseline phase was 81.0 ± 9.9, nasoendoscopic phase was 72.7 ± 10.1, and recovery phase was 75.2 ± 9.6. Sixteen subjects (30.2%) had a positive nasocardiac reflex, and they remained in sinus rhythm with no occurrences of skipped beats, atrioventricular blocks or asystoles. One subject (1.9%) developed temporary ectopic premature ventricular contractions after nasoendoscopy. No variables were found affecting the incidence of a nasocardiac reflex in our study.

    CONCLUSIONS: The pattern of heart rate dynamics was consistent as heart rates drop rapidly upon endoscope insertion and recover in some measure after its withdrawal. Although all our subjects remained asymptomatic, clinicians should not overlook the risks of a severe nasocardiac reflex when performing nasoendoscopy. We recommend that electrical cardiac monitoring be part of the management of vasovagal responses during in-office endonasal procedures.

    Matched MeSH terms: Electrocardiography*
  16. The electrocardiogram of healthy young Chinese and Malay men
    Burns-Cox CJ, Lau LC, Toh BH
    J Electrocardiol, 1971;4(3):211-9.
    PMID: 5126628
    Matched MeSH terms: Electrocardiography*
  17. Fulltext The effects of ageing and adrenergic challenge on electrocardiographic phenotypes in a murine model of long QT syndrome type 3
    Chadda KR, Ahmad S, Valli H, den Uijl I, Al-Hadithi AB, Salvage SC, et al.
    Sci Rep, 2017 09 11;7(1):11070.
    PMID: 28894151 DOI: 10.1038/s41598-017-11210-3
    Long QT Syndrome 3 (LQTS3) arises from gain-of-function Nav1.5 mutations, prolonging action potential repolarisation and electrocardiographic (ECG) QT interval, associated with increased age-dependent risk for major arrhythmic events, and paradoxical responses to β-adrenergic agents. We investigated for independent and interacting effects of age and Scn5a+/ΔKPQ genotype in anaesthetised mice modelling LQTS3 on ECG phenotypes before and following β-agonist challenge, and upon fibrotic change. Prolonged ventricular recovery was independently associated with Scn5a+/ΔKPQ and age. Ventricular activation was prolonged in old Scn5a+/ΔKPQ mice (p = 0.03). We associated Scn5a+/ΔKPQ with increased atrial and ventricular fibrosis (both: p 
    Matched MeSH terms: Electrocardiography
  18. Fulltext The effect of wearing sanitary napkins of different thicknesses on physiological and psychological responses in Muslim females
    Mohamed NG, Abidin NZ, Law KS, Abe M, Suzuki M, Muhamed AM, et al.
    J Physiol Anthropol, 2014;33:28.
    PMID: 25189184 DOI: 10.1186/1880-6805-33-28
    Menstruation is associated with significant unpleasantness, and wearing a sanitary napkin (SN) during menses causes discomfort. In addition, many Muslim women use a thick type of SN during menses due to the religious requirement that even disposable SNs be washed before disposal. Therefore, the objective of this study was to measure the physiological and psychological responses to wearing SNs of different thicknesses during menstruation and non-menstruation phases at rest and during physical activity/exercise among Muslim women.
    Matched MeSH terms: Electrocardiography, Ambulatory
  19. Fulltext The comparison of QT dispersion and 24 hour ambulatory blood pressure monitoring amongst diabetic patients with and without microalbuminuria
    Yeo CK, Hapizah MN, Khalid BAK, Wan Nazainimoon WM, Khalid Y
    Med J Malaysia, 2004 Jun;59(2):185-9.
    PMID: 15559168
    Diabetes mellitus is an important coronary artery disease risk factor. The presence of microalbuminuria, which indicates renal involvement in diabetic patients, is associated with an increased cardiovascular risk. There are suggestions that diabetic patients with microalbuminuria have more adverse risk profile such as higher ambulatory blood pressure and total cholesterol levels to account for the increased cardiovascular morbidity and mortality. QT dispersion is increasingly being recognized as a prognostic factor for coronary artery disease and sudden death. Some studies have suggested that QT dispersion is an important predictor of mortality in Type II diabetic patients. Our cross sectional study was to compare the QT dispersion and 24 hour ambulatory blood pressure monitoring between diabetic patients with microalbuminuria and those without microalbuminuria. Diabetic patients with overt coronary artery disease were excluded from the study. A total of 108 patients were recruited of which 57 patients had microalbuminuria and 51 were without microalbuminuria. The mean value of QT dispersion was significantly higher in patients with microalbuminuria than in patients without microalbuminuria (58.9 +/- 27.9 ms vs. 47.1 +/- 25.0 ms, p < 0.05). The mean 24 hour systolic and diastolic blood pressures were significantly higher in patients with microalbuminuria than in patients without microalbuminuria (129.5 +/- 12.3 mm Hg vs 122.3 +/- 10.2 mm Hg, p < 0.05 and 78.4 +/- 6.9 mm Hg vs 75.3 +/- 6.8 mm Hg, p < 0.05, respectively). Our study suggests that QT dispersion prolongation, related perhaps to some autonomic dysfunction, is an early manifestation of cardiovascular aberration in diabetic patients with microalbuminuria. The higher blood pressure levels recorded during a 24-hour period min diabetics with microalbuminuria could also possibly account for the worse cardiovascular outcome in this group of patients.
    Matched MeSH terms: Electrocardiography*
  20. The clinical benefit of cardiac resynchronization therapy for narrow QRS compared to broad QRS complex patients
    Yap LB, Qadir F, Nguyen ST, Ma SK, Koh KW, Muhammad Z, et al.
    Int J Cardiol, 2015 Mar 15;183:178-9.
    PMID: 25666128 DOI: 10.1016/j.ijcard.2015.01.042
    Matched MeSH terms: Electrocardiography/methods
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