Displaying publications 1 - 20 of 818 in total

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  1. Lam KL
    Family Practitioner, 1983;6:33-36.
    Matched MeSH terms: Prognosis
  2. Khang NC, Ahmad Rafizi H, Zainal Ariffin A, Chye PC
    Med. J. Malaysia, 2014 Dec;69(6):273-4.
    PMID: 25934958 MyJurnal
    Giant lipomatous lesions of the thigh swelling with extension into retroperitoneum are rare. Lesions can be malignant or benign and can have similar clinical presentation. Treatments options differ and their prognosis varies with histology. We present two cases of liposarcoma and lipoma with the same clinical presentations that underwent surgical resection.
    Matched MeSH terms: Prognosis
  3. Kampan N, Irianta T, Djuana A, Pei Shan L, Hashim Omar M, Hatta Mohd Dali AZ
    Case Rep Obstet Gynecol, 2012;2012:134032.
    PMID: 22645693 DOI: 10.1155/2012/134032
    Growing teratoma syndrome is rare and usually it occurs in the younger aged group. The use of chemotherapy following initial surgical resection will yield the diagnosis following tumour enlargement. Complete resection is usually curative and renders better prognosis.
    Matched MeSH terms: Prognosis
  4. Kanaganayagam A
    Med. J. Malaysia, 1980 Dec;35(2):139-43.
    PMID: 7266407
    A 17 year old male with ataxia telangiectasia [Louis-Bar Syndrome] is presented here with a review of the literature with regards to the mode of inheritance, clinical manifestations, diagnosis and treatment of this disorder.
    Matched MeSH terms: Prognosis
  5. Aithala, Gururaj
    Medical Health Reviews, 2008;2008(1):5-16.
    MyJurnal
    Epilepsy is a common neurological disorder in childhood. In a majority, the cause of epilepsy remains a mystery in spite of extensive investigations. The aim of drug treatment is to effectively stop the seizures with minimum of side effects, causing no impairment of long term learning abilities of the child. Up to 30% of children with epilepsy may continue to have seizures in spite of adequate drug therapy. In this review, an overview of the recent advances that affect the diagnosis, prognosis and therapy of childhood epilepsy including the dilemmas of everyday practice is presented.
    Matched MeSH terms: Prognosis
  6. Chan DP
    Med J Malaya, 1965 Sep;20(1):29-35.
    PMID: 4221408
    Matched MeSH terms: Prognosis*
  7. Chow TJ, Tee SF, Yong HS, Tang PY
    Neuropsychobiology, 2016;73(4):233-240.
    PMID: 27305091
    Age at onset (AAO) is a known prognostic indicator for schizophrenia and is hypothesized to correlate with cognition and symptom severity. TCF4 and AKT1 are schizophrenia risk genes involved in cognitive functions. The current study examined the interactive effects of TCF4 and AKT1 variants with gender, family history of psychiatric disorders and ethnicity on the AAO of schizophrenia.
    Matched MeSH terms: Prognosis
  8. Nguyen DV, Muda AS, Yaacob Y
    Malays J Med Sci, 2013 May;20(3):71-7.
    PMID: 23966829 MyJurnal
    Mesenchymal chondrosarcoma is a rare disease with poor prognosis. Treatment including wide or radical excision is very important. Radiotherapy and chemotherapy are additional treatment options, but no conclusive results for their efficacy have been shown until date. Imaging modalities can give important clues for diagnosis and management planning. Angioembolization before surgery could be useful as prophylaxis to control intraoperative bleeding, increasing the likelihood of complete resection.
    Matched MeSH terms: Prognosis
  9. Abdullah Suhaimi SN, Nazri N, Nani Harlina ML, Md Isa N, Muhammad R
    Malays J Med Sci, 2015 Jul-Aug;22(4):69-72.
    PMID: 26715910 MyJurnal
    Papillary thyroid carcinoma (PTC) associated with familial adenomatous polyposis (FAP) is rare. It is usually associated with the cribriform-morular variant of PTC, with unusual patterns on detailed histology examination. This variant is known to have a good prognosis. Papillary thyroid carcinoma associated with FAP commonly occurs in females in their 30s and rarely in the elderly. We report a case of a 69-year-old female presenting with thyroid swelling and a history of FAP.
    Matched MeSH terms: Prognosis
  10. Kan CH, Saffari M, Khoo TH
    Malays J Med Sci, 2009 Oct;16(4):25-33.
    PMID: 22135509 MyJurnal
    Traumatic Brain Injury (TBI) in children has been poorly studied, and the literature is limited. We evaluated 146 children with severe TBI (coma score less than 8) in an attempt to establish the prognostic factors of severe TBI in children.
    Matched MeSH terms: Prognosis
  11. Kua Ch, Abdul Aziz Y
    Biomed Imaging Interv J, 2008 Oct;4(4):e24.
    PMID: 21611013 DOI: 10.2349/biij.4.4.e24
    Presence of air in the kidney can be problematic as the location of the air in different parts of the kidney greatly affects the subsequent management and outcome of the patient. We present here a case of a patient who had emphysematous pyelitis, in which CT scan was able to display presence of air only in the collecting system, thus differentiating this condition from the more fulminant emphysematous pyelonephritis. This leads to a more favourable prognosis and outcome to the patient.
    Matched MeSH terms: Prognosis
  12. Cheong SK, Ainoon O
    Med. J. Malaysia, 1987 Dec;42(4):272-5.
    PMID: 3454399
    Myelodysplastic syndromes appear to be a rare group of blood disorders in Malaysia. It usually affects the elderly and some of the cases were reported to evolve into acute leukemia. We describe our experience with five cases, seen and managed by us over a 5-year period. All patients receiving supportive therapy died with one of them definitely known to transform to acute leukemia. The patient who survives till the time of writing received low dose continuous cytosine arabinoside infusion.
    Matched MeSH terms: Prognosis
  13. Nor Kamaruzaman Esa, Kahairi Abdullah, Shamim Rahman Abdul Rasheed
    MyJurnal
    Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is relatively a rare tumour of head and
    neck region. Without histopathological confirmation, it appears and behaved as like malignant epithelial tumor of
    the head and neck region as will be illustrated in the present case. Cutaneous involvement of the tumor with
    distant metastasis has made the prognosis unfavorable. This isolated case of head and neck PC-ALCL was
    highlighted as it has a tendency to behave aggressively and early diagnosis and treatment is crucial to avoid poor
    survival outcome.
    Matched MeSH terms: Prognosis
  14. Pooi, A.H.
    MyJurnal
    This paper offers a technique to construct a prediction interval for the future value of the last variable in the vector r of m variables when the number of observed values of r is small. Denoting r(t) as the time-t value of r, we model the time-(t+1) value of the m-th variable to be dependent on the present and l-1 previous values r(t), r(t-1), …, r(t-l+1) via a conditional distribution which is derived from an (ml+1)-dimensional power-normal distribution. The 100(α / 2)% and 100(1−α / 2)% points of the conditional distribution may then be used to form a prediction interval for the future value of the m-th variable. A method is introduced to estimate the above (ml+1)-dimensional power-normal distribution such that the coverage probability of the resulting prediction interval is nearer to the target value 1- α .
    Matched MeSH terms: Prognosis
  15. Apparau D, Apparau H, Mohamad I, Bhavaraju VMK
    AME Case Rep, 2018;2:4.
    PMID: 30264000 DOI: 10.21037/acr.2018.01.06
    Malignant melanoma (MM) of parotid gland is a rare condition. This pathology is often a result of secondary metastasis from primary lesions in the head and neck skin. A MM arising de novo in parotid gland is very rare. This malignant tumour is more prevalent in adults rather than children and it tends to have several distinct features. Treatment options are limited especially for an advanced lesion. Despite best treatments this condition carries a poor prognosis. This case details our experience in treating a child with MM of parotid gland without other primary cutaneous lesions.
    Matched MeSH terms: Prognosis
  16. Siti Norasikin Mohd Nafi
    MyJurnal
    Resistance to anti-HER2 targeted therapy imposes a crucial limitation to the successful treatment of HER2 positive breast cancer. The expression of HER4 and its prognostic value is controversial in breast cancer. The role of HER4 in trastuzumab treatment and resistance in HER2-positive breast cancer has been recently studied. HER4 activation, cleavage and nuclear translocation have been demonstrated mediate trastuzumab resistance in HER2 positive breast cancer. In addition, nuclear HER4 is suggested could be a novel predictive and prognostic biomarker in HER2 positive breast cancer patients. Understanding the role of HER4 may offer useful insights to cancer treatment in HER2-positive breast cancer and other cancers.
    Matched MeSH terms: Prognosis
  17. Nurasyikin, Y., Azma, R.Z., Suria, A.A., Chandramaya, S., Noraidah, M., Omayma, S.E.B
    Medicine & Health, 2017;12(1):66-82.
    MyJurnal
    Acute myeloid leukaemia (AML) is the most common subtype of acute leukaemias with a poor outcome. Msi2 protein is a newly discovered prognostic marker and it has been considered as a new target for therapy in AML. The study of Msi2
    protein expression in AML cases has not been performed in Malaysia, to date. The main aim of the present study was to observe the expression of Msi2 protein in AML patients by immunohistochemistry (IHC) and to correlate its expression
    with the well-established prognostic and clinical parameters in AML as well as the overall survival (OS). Sixty four bone marrow trephine biopsy sections were immunostained for Msi2 protein. The percentage of blasts with positive reaction
    and the intensity of the cytoplasmic and nuclear staining were evaluated. The expression of Msi2 protein was found in 95.3% cases with Msi2 pattern varying between the cases. In 71.9% of cases, the blasts showed total cellular positivity and 23.4% cases showed only cytoplasmic positivity. Majority showed high expression of Msi2 for cytoplasmic staining. Interestingly, there was significant correlation between total cellular staining and the intermediate cytogenetic subgroup (P=0.04). In conclusion, the results showed that the majority of the patients had high expression of Msi2 but this did not correlate to OS. However, the Msi2 expression correlated to the cytogenetic findings. The results suggest future extensive research to be conducted in order to ascertain the exact role of Msi2 positive blast cells in AML in our population and their association with prognosis and outcome.
    Keywords: AML, cytogenetics, immunohistochemistry, Msi2 protein
    Matched MeSH terms: Prognosis
  18. Sachithanandan A, Nor Y
    Med. J. Malaysia, 2013 Apr;68(2):175-6.
    PMID: 23629571 MyJurnal
    Synchronous primary non-small cell lung cancers (NSCLC) are rare and may be discovered unexpectedly following lung resection. Discrimination from intrapulmonary metastases is important to guide treatment and prognosis but is difficult solely on clinical or radiological findings. Histopathological evaluation with immunohistochemistry (IHC) markers can prove decisive and should feature in the diagnostic algorithm of such patients. We report a rare case of two synchronous primary NSCLCs diagnosed post operatively following pathological examination of the resected lobe, highlighting the value of IHC and discuss the management of such patients.
    Matched MeSH terms: Prognosis
  19. Aimanan K, Kumar KS, Mohd Arif MN, Noor Zuraini M, Ramdzan MJ, Hamdan L
    Case Rep Med, 2016;2016:4125295.
    PMID: 26904128 DOI: 10.1155/2016/4125295
    Primary lymphomas of the heart are extremely rare, accounting for 2% of all primary cardiac tumors. Due to the rare presentation, there is no proper consensus available on treatment strategy. Preoperative confirmation of the pathology is fundamental in guiding an early treatment plan, which allows for improved prognosis. Unfortunately, in most cases, primary cardiac lymphoma is only identified on postoperative histopathological analyses, which affect the treatment plan and outcome. Here, we report a unique case of primary cardiac lymphoma presented with dyspnea and reduced effort tolerance. Young age, rapid onset of symptom, and absence of cardiac risk factors prompted us towards further imaging and emergency resection. The patient received a course of postoperative chemotherapy and was disease-free on six months of follow-up.
    Matched MeSH terms: Prognosis
  20. Islam MR, Abdullah JM
    Malays J Med Sci, 2014 Dec;21(Spec Issue):34-40.
    PMID: 25941461 MyJurnal
    Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are a prognostic genetic model of absence epilepsy. This model displays the electro-clinical, behavioural, and pharmacological features of absence seizures. Although GAERS share typical characteristics, including spike-and-wave discharges (SWDs) in the electroencephalography (EEG), age-dependent studies with these animals have not yet been reported. The aim of the present study is to perform a systematic comparison contrasting the SWDs of young and older GAERS, in terms of the number, duration, frequency, and waveform morphology of the discharges, as well as the pre-SWD EEG characteristics, using identical measurement and analysis techniques. The number, cumulative total duration and mean duration of SWDs were significantly higher in young GAERS (4 to 6 months) compared to older GAERS (12 to 14 months). Furthermore, the SWD spectra and average SWD waveforms indicated that a single cycle of the SWD contains more energy in faster components, such as increased spikes and higher power, in the SWDs of the young GAERS. Additionally, older GAERS showed weak amplitude spikes in SWDs and higher power pre-SWDs. These clear morphological differences in the EEGs of young and older GAERS rats should be further examined in future studies that explore new dimensions of genetic absence epilepsy.
    Matched MeSH terms: Prognosis
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