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Susceptible and protective HLA class 1 alleles against dengue fever and dengue hemorrhagic fever patients in a Malaysian population

Appanna R 1 , Ponnampalavanar S , Lum Chai See L , Sekaran SD

Affiliations 

  • 1 Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
PLoS One, 2010;5(9).
PMID: 20927388 DOI: 10.1371/journal.pone.0013029

Abstract

The human leukocyte antigen alleles have been implicated as probable genetic markers in predicting the susceptibility and/or protection to severe manifestations of dengue virus (DENV) infection. In this present study, we aimed to investigate for the first time, the genotype variants of HLA Class 1(-A and -B) of DENV infected patients against healthy individuals in Malaysia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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