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Clinical and immunological markers of dengue progression in a study cohort from a hyperendemic area in Malaysia

Rathakrishnan A 1 , Klekamp B 2 , Wang SM 3 , Komarasamy TV 1 , Natkunam SK 4 , Sathar J 5 Show all authors , Azizan A 2 , Sanchez-Anguiano A 2 , Manikam R 6 , Sekaran SD 1

Affiliations 

  • 1 Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, United States of America
  • 3 Institute of Medical Molecular Biotechnology, Faculty of Medicine, University Technology Mara, Selangor, Malaysia
  • 4 Hospital Tengku Ampuan Rahimah, Persiaran Tengku Ampuan Rahimah, Klang, Selangor
  • 5 Clinical Hematology Laboratory, Department of Hematology, Hospital Ampang, Ampang, Selangor, Malaysia
  • 6 Department of Trauma and Emergency Medicine, University Malaya Medical Centre, Kuala Lumpur, Malaysia
PLoS One, 2014;9(3):e92021.
PMID: 24647042 DOI: 10.1371/journal.pone.0092021

Abstract

With its elusive pathogenesis, dengue imposes serious healthcare, economic and social burden on endemic countries. This study describes the clinical and immunological parameters of a dengue cohort in a Malaysian city, the first according to the WHO 2009 dengue classification.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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