Fulltext

Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes

Chow WZ 1 , Chan YF 2 , Oong XY 1 , Ng LJ 3 , Nor'E SS 4 , Ng KT 1 Show all authors , Chan KG 5 , Hanafi NS 6 , Pang YK 1 , Kamarulzaman A 1 , Tee KK 2

Affiliations 

  • 1 Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Faculty of Information Science &Technology, Multimedia University, Melaka, Malaysia
  • 4 Tropical Infectious Diseases Research &Education Centre (TIDREC), Deputy Vice Chancellor (Research &Innovation), University of Malaya, Kuala Lumpur, Malaysia
  • 5 Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 6 Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Sci Rep, 2016 06 09;6:27730.
PMID: 27279080 DOI: 10.1038/srep27730

Abstract

Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV prevailed at 2.2% (n = 86/3,935) among individuals presented with acute respiratory tract infections in Kuala Lumpur, Malaysia between 2012 and 2014. Seasonal peaks were observed during the northeast monsoon season (November-April) and correlated with higher relative humidity and number of rainy days (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications