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Prevalence and incidence of liver dysfunction and assessment of biomarkers of liver disease in HIV-infected Asian children

Aurpibul L 1 , Bunupuradah T , Sophan S , Boettiger D , Wati DK , Nguyen LV Show all authors , Saphonn V , Hansudewechakul R , Chokephaibulkit K , Lumbiganon P , Truong KH , Do VC , Kumarasamy N , Yusoff NK , Razali K , Kurniati N , Fong SM , Nallusamy R , Sohn AH , TREAT Asia Pediatric HIV Observational Database

Affiliations 

  • 1 *Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; †HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand; ‡TB/HIV Department, National Pediatric Hospital, Phnom Penh, Cambodia; §The Kirby Institute, University of New South Wales, Sydney, Australia; ¶Department of Child Health, Sanglah Hospital, Udayana University, Bali, Indonesia; ‖Infectious Disease Department, National Hospital of Pediatrics, Hanoi, Vietnam; **Research Unit, National Center for HIV/AIDS, Dermatology and STDs, Social Health Clinic, Phnom Penh, Cambodia; ††Faculty of Medicine, University of Health Sciences, Phnom Penh, Cambodia; ‡‡Department of Pediatrics, Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand; §§Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; ¶¶Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; ‖‖Infectious Disease Department, Children's Hospital 1, Ho Chi Minh City, Vietnam; ***Infectious Disease Department, Children's Hospital 2, Ho Chi Minh City, Vietnam; †††Y.R. Gaitonde Centre for AIDS Research and Education (YRG CARE), Chennai, India; ‡‡‡Department of Pediatrics, Hospital Raja Perempuan Zainab II, Kelantan, Malaysia; §§§Pediatric Institute, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia; ¶¶¶Pediatric Allergy-Immunology Division, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; ‖‖‖Department of Pediatrics, Hospital Likas, Kota Kinabalu, Malaysia; ****Department of Pediatrics, Penang Hospital, Penang, Malaysia; and ††††TREAT Asia/amfAR-The Foundation for AIDS Research, Bangkok, Thailand
Pediatr Infect Dis J, 2015 Jun;34(6):e153-8.
PMID: 25970117 DOI: 10.1097/INF.0000000000000693

Abstract

We determined the prevalence and incidence of liver dysfunction before and after initiation of combination antiretroviral therapy (cART) in the TREAT Asia Pediatric HIV Observational Database.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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