Affiliations 

  • 1 Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  • 2 D.Y. Patil University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra State, India
  • 3 KBHs MGV Dental College & Hospital, Nasik, Maharashtra State, India
  • 4 Modern Dental College, Indore, Madhya Pradesh, India
  • 5 International Medical University, School of Pharmacy, Department of Pharmaceutical Technology, 57000 Kuala Lumpur, Malaysia
  • 6 Faculty of Pharmacy, Lincoln University College, Petalling Jaya, Selangor, Kuala Lumpur 47301, Malaysia
  • 7 International Medical University, School of Pharmacy, Department of Pharmaceutical Technology, 57000 Kuala Lumpur, Malaysia. Electronic address: prashantdops@gmail.com
Mater Sci Eng C Mater Biol Appl, 2018 Oct 01;91:881-898.
PMID: 30033323 DOI: 10.1016/j.msec.2018.05.069

Abstract

Oral cavity is a gateway to the entire body and protection of this gateway is a major goal in dentistry. Plaque biofilm is a major cause of majority of dental diseases and although various biomaterials have been applied for their cure, limitations pertaining to the material properties prevent achievement of desired outcomes. Nanoparticle applications have become useful tools for various dental applications in endodontics, periodontics, restorative dentistry, orthodontics and oral cancers. Off these, silver nanoparticles (AgNPs) have been used in medicine and dentistry due to its antimicrobial properties. AgNPs have been incorporated into biomaterials in order to prevent or reduce biofilm formation. Due to greater surface to volume ratio and small particle size, they possess excellent antimicrobial action without affecting the mechanical properties of the material. This unique property of AgNPs makes these materials as fillers of choice in different biomaterials whereby they play a vital role in improving the properties. This review aims to discuss the influence of addition of AgNPs to various biomaterials used in different dental applications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.