Displaying publications 901 - 920 of 2448 in total

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  1. Fulltext A dilemma in management of intrauterine death in mother with major placenta previa
    Rima Anggrena, D., Yulianty, A., Nor Azlin, M.I.
    Journal of Surgical Academia, 2017;7(2):43-45.
    MyJurnal
    Placenta previa is a condition when the placental tissue extends over the internal cervical os. It is associated with
    maternal and fetal morbidity and mortality. With intrauterine death, the mode of delivery will be more difficult to
    decide. Here, we report a case of 30 years old G3P2 with placenta previa major diagnosed with intrauterine death at
    29 weeks gestation who was managed conservatively and delivered vaginally with minimal complication. A good
    patient selection and thorough counseling, patient with placenta previa major and intrauterine death still can be safely
    delivered vaginally.
    Matched MeSH terms: Pregnancy
  2. Fulltext Antenatal care practice and pregnancy outcome at Sikuati Area, Kudat, Sabah
    Tin Tin Aye, Yusolf Ibrahim, Daw Khin Saw Naing, Than Myint, Muhammad Hj. Jical
    Borneo Journal of Medical Sciences, 2016;10(2):26-38.
    MyJurnal
    Antenatal (AN) care is vital for all pregnant women and for reduction of maternal mortality and morbidity. AN care knowledge and specific AN care practices are some of the crucial components of what determines effective AN care. In developing nations, the health of pregnant women can be even more sensitive to these factors. Objectives of this study was to assess the antenatal (AN) care practice and pregnancy outcome of ever-married women aged 18 to 49 years old having at least one pregnancy experience ,residing in kampongs of Sikuati area, Kudat between March to December 2015. Cross–sectional descriptive study, non-probability convenient sampling method was used and 150 eligible participants were interviewed through face to face by trained interviewers using a semi-structured questionnaire and their knowledge of AN care, their AN care practices and outcomes and complications of their pregnancies were recorded. 99% of all the women received AN care, and 64% of the women received essential AN care practice (AN visit of minimum 4 times). The study revealed that overall knowledge amongst the women with good knowledge was 48% and low knowledge was 52%. Despite this, it was found that low knowledge of AN care was associated with essential AN care practice. Additionally, AN care practices, assessed through timing of first AN care visit and frequency of visits, was not significantly associated with pregnancy complications. Despite these results, outcomes were good and all complications were properly and successfully addressed. This may reflect the effectiveness of current programs in place promoting importance of AN care and delivery practices. Maintenance of current programs with targeted interventions to address low knowledge level and the low level of compliance with essential AN care completed are recommended..
    Matched MeSH terms: Pregnancy
  3. Fulltext Down syndrome and Patau syndrome in the same sibship: random or not?
    Foong Eva, Hasliani Hassan, Azizah Othman, Ilunihayati Ibrahim, Nazihah Mohd Yunus, Siti Mariam Ismail, et al.
    Malaysian Journal of Paediatrics and Child Health, 2017;23(2):0-0.
    MyJurnal
    Objectives: Chromosomal abnormalities especially aneuploidies are the most common etiology for pregnancy loss. Trisomy 13, trisomy 18 and trisomy 21 are the most common chromosome autosomal aneuploidies with trisomy 21 (Down syndrome) being the most common chromosomal abnormality among liveborn infants. In previous reports, we noted that the recurrence of these aneuploidies in some families may not occur by chance alone.

    Methods: Extraction of relevant data from review of medical case notes of a young couple with two offspring with Down syndrome (DS) and Patau syndrome.

    Results: A family history of DS is a predisposing factor for both DS and other types of aneuploidy. Certain instances of non-disjunction error are not random.

    Conclusion: As the maternal age was not advanced in both pregnancies, there is a possibility that the recurrent aneuploidy in this family may not be accounted by chance alone. The risk of having subsequent affected pregnancy cannot be ignored in this family and prenatal diagnosis is strongly recommended in the subsequent pregnancy.
    Matched MeSH terms: Pregnancy
  4. Fulltext Retrospective study on neonates of dengue positive mother over a period of one year
    Chang JV, Lim KY, Ang EL
    Malaysian Journal of Paediatrics and Child Health, 2016;22(1):35-42.
    MyJurnal
    Objectives: This is a retrospective study in which all neonates with confirmed dengue fever mother admitted to our special care nursery from March 2014 to March 2015 were recruited. This is to determine the percentage of positive dengue serology in the neonates of mother with confirmed dengue fever and to investigate the correlation between the duration of maternal illness with these neonatal seropositivity of dengue antibody and their presenting symptoms.

    Method: A total of 22 neonates whose mother with confirmed dengue fever were recruited out of which 14 (63.6%) neonates of confirmed dengue fever mothers had positive dengue serology.

    Results: Eight out of fourteen neonates were dengue seropositive when mother dengue illness was between day 1 to 5 of illness (acute phase) at the time of delivery. Thirteen out of twenty-two neonates (59%) were symptomatic, out of which 61.5% (8 out of 13) were delivered during maternal acute phase of illness.

    Conclusion: From this study, we concluded that neonates were more likely to be dengue seropositive and symptomatic when mother presented in acute phase of illness during delivery. However, our sample size was small, only 22 neonates were recruited from a single centre, therefore a larger sample size from multicentre is required in future.
    Matched MeSH terms: Pregnancy
  5. Evaluation of workshop for training house-officers and medical officers on medical emergencies using simulation for workplace preparedness
    Thiruselvi Subramaniam, Ann Jee Tan
    International e-Journal of Science, Medicine & Education, 2017;11(1):33-38.
    MyJurnal
    Background: House-officers and medical officers are at
    the forefront during medical emergencies in the ward
    and casualty which impose cognitive, communication,
    social and system challenges and yet, training in this
    area is commonly lacking. A workshop was conducted
    using simulation to provide training on some acute
    medical emergencies like cord prolapse, post- partum
    haemorrhage with collapse, poly-trauma and acute
    exacerbation of asthma.

    Objective: To determine the effectiveness of simulation
    in developing competency in managing selected clinical
    emergencies.

    Methodology: There were 22 participants consisting
    of house-officers, junior medical officers and nursing
    clinical instructors. Only doctors were included in
    the study. Four medical emergencies were chosen viz.:
    Cord prolapse; post- partum haemorrhage with collapse;
    poly-trauma and acute exacerbation of asthma. The
    simulated sessions were conducted using high fidelity
    manikins and simulated patients. Simulated patients
    were trained and moulage was applied accordingly. The
    skills stations were on airway equipment and techniques
    of application, latest cardiac life support algorithm and
    hands on chest compression using manikins.

    Results: A 5 point Likert scale used to rate the
    sessions. The skills station had 65% (n=13) rating as
    excellent and 35% (n=7) good. The skills simulation
    was rated excellent by 75% (n=15) and good by 25%
    (n=5) of participants. Verbal feedback was that it was
    very refreshing, informative, and helpful in terms of
    improving their skills.

    Conclusion: The simulated skills training for the junior
    doctors was very well received and maybe beneficial for
    work preparedness and in the long run address patient
    safety.
    Matched MeSH terms: Pregnancy
  6. Fulltext Sickle cell disease in pregnancy – a rare condition with detrimental outcome: a case report
    Nik Sumayyah, N. M. N., Shafiee, M. N., Kalok, A., Nagandla, K.
    Medicine & Health, 2017;12(2):352-356.
    MyJurnal
    Sickle cell disease (SCD) in pregnancy is uncommon in Malaysia. We present a case of sickle cell disease in pregnancy with maternal and fetal complications. The patient presented with acute pain crisis and hemolysis in the third trimester. Despite thromboprophylaxis, she developed deep vein thrombosis. The pregnancy was further complicated by severe pre-eclampsia and intrauterine growth restriction which require preterm caesarean section. The baby was admitted to Neonatal Intensive Care Unit due to prematurity and low birth weight. Multidisciplinary
    approach in managing pregnant patient with SCD is essential in achieving good obstetrics outcome.
    Keywords: anemia, sickle cell disease, pregnancy outcomes
    Matched MeSH terms: Pregnancy
  7. Fulltext Case control study of anxiety and depression among patients with miscarriage compared to those with successful pregnancy
    Ng, B. K., Chuah, J. N., Lim, P. S., Shuhaila, A., Marhani, M., Nor Azlin, M. I.
    Medicine & Health, 2017;12(2):244-258.
    MyJurnal
    Miscarriage is one of the most common complications in pregnancy. There is emerging evidence that psychological impact following miscarriage is not unusual. Understanding the magnitude of psychological morbidity is important in the management of miscarriage. The main objective of this study was to compare the mean Hospital Anxiety and Depression Scale (HADS) score between women with miscarriage and women with successful pregnancy and to determine the sociodemographic factor and clinical characteristic that are associated with anxiety and depression. A descriptive case control study was conducted in a teaching hospital, over a period of 12-months (from October 2014 till September 2015). A total of 65 women were recruited with 32 women as the study group (miscarriage) and another 33 women as the control group (women with successful pregnancy). Mean HADS-anxiety score was higher in the study group compared to control group although it was not statistically significant (6.53 ± 3.427 vs 5.73 ± 2.875, p=0.309). Mean HADS-depression score was higher in the control group (4.34 ± 2.695 vs 4.45 ± 3.073, p=0.878). Women with maternal age more than 35 years and history of previous miscarriage had a higher tendency of anxiety and depression with higher mean HADS score. There was no association between other sociodemographic data and clinical characteristic with risk of anxiety and depression. As conclusion, there was no significant difference in women with miscarriage as compared to those with successful pregnancies, although older women with history of miscarriage had a preponderance to both disorders.
    Keywords: anxiety, depression, miscarriage, morbidity, psychological
    Matched MeSH terms: Pregnancy
  8. Fulltext Anti-G with concomitant anti-C and anti-D: A case report in a pregnant woman
    Yousuf R, Mustafa AN, Ho SL, Tang YL, Leong CF
    Asian J Transfus Sci, 2017 3 21;11(1):62-64.
    PMID: 28316444 DOI: 10.4103/0973-6247.200770
    The G antigen of Rh blood group system is present in almost all D-positive or C-positive red cells but absent from red cells lacking D and C antigens. The differentiation of anti-D and anti-C from anti-G is not necessary for routine transfusion; however, during pregnancy, it is important because anti-G can masquerade as anti-D and anti-C with initial antibody testing. The false presence of anti-D will exclude the patient from receiving anti-D immunoglobulin (RhIG) when the patient actually is a candidate for RhIG prophylaxis. Moreover, patients with positive anti-D or anti-G are at risk of developing hemolytic disease of the fetus and newborn and need close monitoring. Thus, proper identification allows the clinicians to manage patients properly. This case report highlights a rare case of anti-G together with anti-D and anti-C in a pregnant woman. This report disseminates knowledge on identification of anti-G and its importance in pregnant women.
    Matched MeSH terms: Pregnancy
  9. Pulmonary hypertension complicating systemic sclerosis: A successful pregnancy outcome
    Chew KT, Ahmad MF, Yong SL, Mohamed Ismail NA
    J Obstet Gynaecol, 2017 Jul;37(5):677-678.
    PMID: 28350528 DOI: 10.1080/01443615.2017.1284774
    Matched MeSH terms: Pregnancy
  10. Fulltext Performance of 2 Polymerization Protocols Targeting Cloned Toxoplasma Parasites
    Hanafy NA, Badr MS, Nasr GM
    Open Access Maced J Med Sci, 2018 Sep 25;6(9):1577-1580.
    PMID: 30337968 DOI: 10.3889/oamjms.2018.400
    BACKGROUND: Toxoplasma gondii is a common parasitic infection of humans. Infection is usually mild. Serious complications can occur in pregnant and immunocompromised patients.

    AIM: The present study aims to investigate the performance of 2 different PCR protocols; real-time quantitative molecular assays (qPCR) and conventional molecular assays (cPCR), using 2 different sets of primers and by using cloned purified Toxoplasma genomic substances to be evaluated as reference samples.

    METHODS: The target DNA was provided in 8 different quantities.

    RESULTS: Amplification failure was reported only with the cPCR in samples of low concentrations using both primer sets. Quantitative PCR detected the 8 different dilutions of the purified Toxoplasma gondii using the 2 sets of primers while cPCR was sensitive to detect only 6 different dilutions.

    CONCLUSION: Generally real-time quantitative molecular assays, is easy to use method compared to conventional PCR assay and produces more reliable results within only one hour time but still the possible application of qPCRs in routine diagnosis necessitates analysis of a large number of clinical samples in further studies to make the proper choice.

    Matched MeSH terms: Pregnancy
  11. Fulltext Optic Discs Swelling Procrastinates Wernicke's Encephalopathy Associated with Hyperemesis Gravidarum: A Case Report and Review of Literature
    Mun-Wei L, Gayathri G, Kwang Hwee G, Ruban K, Suresh Kumar V, Shatriah I
    Cureus, 2018 Jun 12;10(6):e2793.
    PMID: 30112269 DOI: 10.7759/cureus.2793
    Wernicke's encephalopathy following severe hyperemesis gravidarum is an uncommon clinical entity. We describe a rare manifestation of optic discs swelling in a pregnant woman that has caused a diagnostic dilemma. With high index of suspicion of clinical manifestations and radiological evidences, a clinical diagnosis of Wernicke's encephalopathy was made. Intravenous thiamine therapy was instituted, and prompt improvement of clinical signs was observed. The association of optic discs swelling and Wernicke's encephalopathy after hyperemesis gravidarum is discussed.
    Matched MeSH terms: Pregnancy
  12. Fulltext Prenatal heating effects of ultrasound: a review
    Nadzirah Mohamad Radzi, Farah Wahida Ahmad Zaiki
    Malaysian Journal of Medicine and Health Sciences, 2018;14(3):39-45.
    MyJurnal
    The application of ultrasound technology has been widely accepted in clinical settings, particularly in Obstetrics and Gynaecology. This is in light of its ability to detect early foetal malformations apart from enabling foetal monitoring throughout gestation. While ultrasonography is an imaging method that is regularly used in Obstetrics, it is questionable as to whether it is safe for foetuses. The purpose of this paper was to review the evidence regarding the thermal effects of ultrasound exposure on foetal development, particularly. It is hoped that the importance of prudent usage of prenatal ultrasonography will be impressed on clinicians and the public in order to avoid the unnecessary usage of ultrasonography when it is not medically indicated. This is so that the welfare of pregnant women will be looked after, besides contributing to the better health of the next generation by ensuring that the benefits outweigh the known risks or potential harms.
    Matched MeSH terms: Pregnancy
  13. Fulltext The awareness of the religious laws regarding breast milk donation: a study conducted among the Muslim community in Selangor
    Norita Kamaruddin, Nora'inan Bahari, Zanariah Dimon, Nurhayati Abd Ghani
    Malaysian Journal of Social Sciences and Humanities, 2018;3(3):168-172.
    MyJurnal
    The awareness of the Muslim community on the importance of understanding breastfeeding according
    to Islamic perspective needs to be emphasized in promoting the implementation of breastfeeding in the
    best way. This proved that breast milk is the major food after birth and a mother should know the right
    and the regulation of breastfeeding in order to be in line with Islamic law. This article aims to discuss
    the level of awareness among the Muslim community in Selangor regarding breast milk donation. Data
    were collected through a questionnaire distributed to 400 respondents involving three locations in
    Selangor, namely in the northern zone (Hulu Selangor district), central zone (Klang district) and
    southern zone (Sepang district). The findings showed that the respondents had a moderate level of
    awareness regarding milk donation laws with average mean value of 3.26. This finding shows that the
    Muslim community in Selangor are concerned about the rights and the regulation of breastfeeding.
    Matched MeSH terms: Pregnancy
  14. Improving undergraduate obstetrics and gynaecology education through the use of WhatsApp™
    Soe MZ, Pang NTP, Loo JL
    Eur J Obstet Gynecol Reprod Biol, 2020 Apr;247:269.
    PMID: 32145995 DOI: 10.1016/j.ejogrb.2020.02.036
    Matched MeSH terms: Pregnancy
  15. Calcium supplementation to decrease the incidence of hypertensive disorders of pregnancy: a review
    Manju K
    Family Physician, 1994;6:6-8.
    Hypertensive disorders of pregnancy is a major cause of fetal and maternal morbidity. Epidemiologic observations have shown an inverse association between calcium intake and incidence of eclampsia. Calcium supplementation has been reported to decrease blood pressure in pregnant women, although this remains controversial. The mechanism responsible for the effect of calcium on hypertinsion in pregnant women is unknown. This paper is a review of some of the recent calcium supplementation trials that have been carried out and their effectiveness in reducing systolic and diastolic blood pressure and decreasing the incidence of hypertensive disorders of pregnancy.
    Matched MeSH terms: Pregnancy
  16. Anaemia during pregnancy in rural Kelantan
    Ahmad Z, Jaafar R, Md Hassan MH, Othman MS, Hashim A
    Family Physician, 1995;7:11-15.
    Anaemia still constitutes a public health problem in the world, especially in the developing countries (1). Nutritional deficiency remains a major causative factor (2). During pregnancy, growth of the foetus, placenta and the larger amount of circulating blood in the expectant mother will lead to an increase in the demand for nutrients, especially iron and folic acid. Many women start their lives with insufficient iron stores, but also, because of inadequate child spacing, they have little time to build up their iron levels between pregnancies. In pregnancy, anaemia has been shown to be associated with an increased risk of maternal and fetal morbidity and mortality (3,4,5). Iron and folic acid supplementation is routinely given to pregnant mothers in Malaysia. It is anticipated that pregnant mothers who comply strictly with the prescribed iron supplement will maintain adequate iron stores at parturition. However, the compliance rate among rural mothers in Kelantan is often poor (6). Kelantan is also one of the most socio-economically underdeveloped
    Matched MeSH terms: Pregnancy
  17. Fulltext Unplanned pregnancies in a semi-urban practice
    Chua WT
    Family Practitioner, 1985;8(2):57-62.
    One hundred and twenty-four women from a semi-urban area who came for consultation for unplanned pregnancy during an eight month period are analysed. It is found that women with a high risk of unplanned pregnancy are mostly housewives, aged between 20 and 34, who have given birth to one or three children, the last of whom is usually below one or two years old. They belong to the lower socio-economic class and are lowly-educated. Most of them have not completed their families. Although most of them have either used or heard of contraceptives begore, the majority were not using any contraceptive at the time of consultation or were using an ineffective method. Their reasons for non-use or default are identified, many of which are related to the pill. Proper motivation of would-be contraceptive receptors and regular follow-up of acceptors by general practitioners or Family Planning Clinic Staff who are knwoledgable in all available methods of contraception are offered as a solutionto the problem of high rate of defaulting and consequent high rate of unplanned pregnancies.
    Study site: private general practice clinic, Perak, Malaysia
    Matched MeSH terms: Pregnancy
  18. Integrated approach for triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis is highly effective and cost-effective: an economic evaluation
    Zhang L, Tao Y, Woodring J, Rattana K, Sovannarith S, Rathavy T, et al.
    Int J Epidemiol, 2019 08 01;48(4):1327-1339.
    PMID: 30879066 DOI: 10.1093/ije/dyz037
    BACKGROUND: The Regional Framework for Triple Elimination of Mother-to-Child Transmission (EMTCT) of HIV, Hepatitis B (HBV) and Syphilis in Asia and the Pacific 2018-30 was endorsed by the Regional Committee of WHO Western Pacific in October 2017, proposing an integrated and coordinated approach to achieve elimination in an efficient, coordinated and sustainable manner. This study aims to assess the population impacts and cost-effectiveness of this integrated approach in the Cambodian context.

    METHODS: Based on existing frameworks for the EMTCT for each individual infection, an integrated framework that combines infection prevention procedures with routine antenatal care was constructed. Using decision tree analyses, population impacts, cost-effectiveness and the potential reduction in required resources of the integrated approach as a result of resource pooling and improvements in service coverage and coordination, were evaluated. The tool was assessed using simulated epidemiological data from Cambodia.

    RESULTS: The current prevention programme for 370,000 Cambodian pregnant women was estimated at USD$2.3 ($2.0-$2.5) million per year, including the duration of pregnancy and up to 18 months after delivery. A model estimate of current MTCT rates in Cambodia was 6.6% (6.2-7.1%) for HIV, 14.1% (13.1-15.2%) for HBV and 9.4% (9.0-9.8%) for syphilis. Integrating HIV and syphilis prevention into the existing antenatal care framework will reduce the total time required to provide this integrated care by 19% for health care workers and by 32% for pregnant women, resulting in a net saving of $380,000 per year for the EMTCT programme. This integrated approach reduces HIV and HBV MTCT to 6.1% (5.7-6.5%) and 13.0% (12.1-14.0%), respectively, and substantially reduces syphilis MCTC to 4.6% (4.3-5.0%). Further introduction of either antiviral treatment for pregnant women with high viral load of HBV, or hepatitis B immunoglobulin (HBIG) to exposed newborns, will increase the total cost of EMTCT to $4.4 ($3.6-$5.2) million and $3.3 ($2.7-$4.0) million per year, respectively, but substantially reduce HBV MTCT to 3.5% (3.2-3.8%) and 5.0% (4.6-5.5%), respectively. Combining both antiviral and HBIG treatments will further reduce HBV MTCT to 3.4% (3.1-3.7%) at an increased total cost of EMTCT of $4.5 ($3.7-$5.4) million per year. All these HBV intervention scenarios are highly cost-effective ($64-$114 per disability-adjusted life years averted) when the life benefits of these prevention measures are considered.

    CONCLUSIONS: The integrated approach, using antenatal, perinatal and postnatal care as a platform in Cambodia for triple EMTCT of HIV, HBV and syphilis, is highly cost-effective and efficient.

    Matched MeSH terms: Pregnancy; Pregnancy Complications, Infectious/epidemiology; Pregnancy Complications, Infectious/prevention & control*
  19. Fetal Atrial Ectopic Rhythm Detected Using Handheld Doppler
    Mohd Jalil R, Radzi NS, Yahaya Z, Muhar M
    Malays Fam Physician, 2020;15(1):50-53.
    PMID: 32284806
    Atrial ectopic rhythm is one of the most common fetal arrhythmias that can present during the prenatal period. Detection of fetal arrhythmia can be made by auscultating fetal heart rate and rhythm using a fetal handheld Doppler, and this can be done even in a resource-limited setting. The finding of an abnormal fetal heart rate and rhythm should prompt early referral to a pediatric cardiologist, as this may improve clinical outcomes. We present a case of atrial ectopic rhythm detected in utero using a handheld Doppler.
    Matched MeSH terms: Pregnancy
  20. Fulltext Selected data on health status of migrant women respondents
    Siti Norazah Z
    JUMMEC, 2002;7(1):15-23.
    Reproductive health is "a state of complete, mental and social well-being in all matters relating to the reproductive system and to its functions and processes. Implicit in this is the right of men and women to be informed and to have access to safe, effective and affordable and acceptable methods of family planning of their choice, as well as other methods of their choice for regulation of fertility, which are not against the law, and the right of access to health-care services that enable women to go safely through pregnancy and childbirth." The survey on Health Problems of Migrant Workers included a section on Women's Health covering aspects of reproductive health. This was based on concerns over reproductive health needs of migrant women workers, particularly since the large majority are in the reproductive age-group, and the utilisation of government healthcare facilities. The latter has implications for the potential burden on public healthcare services in terms of resources and costs. Specifically, the Women's Health section included questions on pregnancy, place of delivery of last baby (born in Malaysia), postnatal care related to this delivery, and mode of payment. For those currently pregnant, questions were asked of sources of antenatal care, postnatal care and respective modes of payment for thsoe services. This section also included questions on current contraceptive practices, source of supplies, and mode of payment for contraceptive methods.
    Matched MeSH terms: Pregnancy
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