Displaying publications 141 - 160 of 963 in total

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  1. Sufian Maryam, Nik Fadzly, Wan Fatma Zuharah
    Trop Life Sci Res, 2016;27(11):95-101.
    MyJurnal
    Paederus fuscipes Curtis is a nocturnal insect. The attractiveness of artificial
    light sources from residential premises eventually causes the risk of severe dermatitis
    effect, once Paederus is in contact with human skin. The objective of this study is to
    investigate whether the light and height factors of residential buildings and its’ association
    to rice cultivation phases are primary reasons for P. fuscipes’s mass dispersal into human
    residential areas. The study site was located in residential premises that were built
    adjacent to rice field areas (≈ 32–60 m and 164 m) north of the rice field located in Teluk
    Air Tawar, mainland of Pulau Pinang. Overall, both light sources and rice cultivation
    phases caused a significant effect for P. fuscipes beetles dispersal flight to invade human
    settlements. More P. fuscipes were captured near the bright light source with the highest
    number of beetles found during harvesting stage. Whereas, significantly higher number of
    P. fuscipes were captured at level 2 and 3 compared to ground and level 1 of the
    apartment building and P. fuscipes was also found significantly affected by the rice
    cultivation phases at different elevation levels. This indicates that bright light sources and
    higher elevation levels are the main factors in attracting P. fuscipes beetles to disperse
    and causes infestations in residential areas. This finding could create awareness among
    the public on P. fuscipes dispersal pattern.
    Matched MeSH terms: Skin
  2. Nair RS, Billa N, Leong CO, Morris AP
    Pharm Dev Technol, 2021 Feb;26(2):243-251.
    PMID: 33274672 DOI: 10.1080/10837450.2020.1860087
    Tocotrienol (TRF) ethosomes were developed and evaluated in vitro for potential transdermal delivery against melanoma. The optimised TRF ethosomal size ranged between 64.9 ± 2.2 nm to 79.6 ± 3.9 nm and zeta potential (ZP) between -53.3 mV to -62.0 ± 2.6 mV. Characterisation of the ethosomes by ATR-FTIR indicated the successful formation of TRF-ethosomes. Scanning electron microscopy (SEM) images demonstrated the spherical shape of ethosomes, and the entrapment efficiencies of all the formulations were above 66%. In vitro permeation studies using full-thickness human skin showed that the permeation of gamma-T3 from the TRF ethosomal formulations was significantly higher (p skin (p skin permeation and high cell viability associated with this formulation suggest a promising carrier for transdermal delivery.
    Matched MeSH terms: Skin/metabolism*; Skin Absorption*
  3. Imrigha NAA, Bidin N, Lau PS, Musa N, Zakaria N, Krishnan G
    J Biophotonics, 2017 Oct;10(10):1287-1291.
    PMID: 28464516 DOI: 10.1002/jbio.201600295
    Q-switched Nd: YAG laser is the most effective laser for tattoo removal. Photobiomodulation (PBM) therapy is an alternative method applied to accelerate the wound healing. This paper investigated the effects of PBM therapy using 808 nm diode laser on tattooed skin after laser tattoo removal. Forty-five rats were selected and tattooed with black ink on their dorsal, and then distributed into three groups. G0 was received non-laser irradiation. G1 was treated by laser tattoo removal using 1064 nm with energy density of 3.4 J/cm2 without PBM therapy, while G2 was treated daily with PBM therapy using 808 nm diode laser of 5 J/cm2 after a single session of laser tattoo removal. The effects of tattoo removal and healing progress of the wound were analyzed using histological studies. Findings showed 808 nm laser promotes the healing process through enhancing epithelialization and collagen deposition. Moreover, PBM therapy stimulated immune cells to improve phagocytosis process for removing the tattoo ink fragments effectively. The PBM therapy treated group was capable of improving the healing process and increasing the quality of skin following the laser tattoo removal. It was also found that stimulation of cellular function by PBM therapy increased tattoo clearance efficiency.
    Matched MeSH terms: Skin/cytology; Skin/metabolism; Skin/radiation effects
  4. Tang ASO, Yong KY, Wong J, Chua HH, Chew LP
    Med J Malaysia, 2017 04;72(2):122-123.
    PMID: 28473676
    This is a case report of subcutaneous mycosis presenting as a non-healing left calf ulcer in an immunocompromised patient. Traumatic inoculation of the causative agent is the most likely route of infection. The diagnosis requires a detailed history and high clinical suspicion, confirmed by histopathological examination. The management requires a multidisciplinary team approach involving surgeon, pathologist, physician sub-specialised in infectious disease, wound care nursing team as well as social support services. The literature review recommended that the treatment of choice for such infection is surgical debridement in addition to optimal antifungal therapy.
    Matched MeSH terms: Skin Ulcer/diagnosis*; Skin Ulcer/etiology; Skin Ulcer/pathology
  5. Alnned M. Mharib, Mohammad Hamiruce Marhaban, Abdul Rahman Ramli
    MyJurnal
    Skin detection has gained popularity and importance in the computer vision community. It is an essential step for important vision tasks such as the detection, tracking and recognition of face, segmentation of hand for gesture analysis, person identification, as well as video surveillance and filtering of objectionable web images. All these applications are based on the assumption that the regions of the human skin are already located. In the recent past, numerous techniques for skin colour modeling and recognition have been proposed. The aims of this paper are to compile the published pixel-based skin colour detection techniques to describe their key concepts and try to find out and summarize their advantages, disadvantages and characteristic features.
    Matched MeSH terms: Skin Pigmentation
  6. Pearson JMH, Pettit JHS, Siltzbach LE, Ridley DS, Hart PD, Rees RJ
    PMID: 5394258
    Kveim tests using a validated material have been undertaken in Malaysia on 39 patients (32 Chinese; 4 Malay and 3 Aboriginal) with lepromatous or tuberculoid leprosy. All the patients had been treated for leprosy, most for two or more years. The tests were read microscopically. Of the 21 lepromatous patients one gave a weak positive and two an equivocal Kveim test whereas four of the nine tuberculoid patients gave equivocal or weak Kveim positivity. Only the tuberculoid form elicits a higher proportion of granulomas than might be expected in a comparable normal population. Of nine patients (8 lepromatous; 1 tuberculoid ) who failed to sensitize well to tuberculin
    following two BCG vaccinations, two gave equivocal Kveim tests similar in appearance to those in the other groups.
    Matched MeSH terms: Skin/pathology; Skin Tests*
  7. Canizares O
    Int J Dermatol, 1979 Sep;18(7):539-44.
    PMID: 387621
    Matched MeSH terms: Skin Diseases/epidemiology*; Skin Diseases, Infectious/epidemiology
  8. Ibrahim SM, Kareem OH, Saffanah KM, Adamu AA, Khan MS, Rahman MBA, et al.
    Cryobiology, 2018 06;82:27-36.
    PMID: 29679551 DOI: 10.1016/j.cryobiol.2018.04.012
    The objective of this study was to evaluate the use of Afp1m as a cryopreservative agent for skin by examining the transplanted skin histological architecture and mechanical properties following subzero cryopreservation. Thirty four (34) rats with an average weight of 208 ± 31 g (mean ± SD), were used. Twenty four (n = 24) rats were equally divided into four groups: (i) immediate non-cryopreserved skin autografts (onto same site), (ii) immediate non-cryopreserved skin autografts (onto different sites), (iii) skin autografts cryopreserved with glycerol for 72 h and (iv) skin autografts cryopreserved with Afp1m for 72 h at -4 °C. Rounded shaped full-thickness 1.5-2.5 cm in diameter skin was excised from backs of rats for the autograft transplantation. Non-cryopreserved or cryopreserved auto skin graft were positioned onto the wound defects and stitched. Non-transplanted cryopreserved and non-cryopreserved skin strips from other ten rats (n = 10) were allowed for comparative biomechanical test. All skin grafts were subjected to histological and mechanical examinations at the end of day 21. Histological results revealed that tissue architecture especially the epidermal integrity and dermal-epidermal junction of the Afp1m cryopreserved skin grafts exhibited better histological appearance, good preservation of tissue architecture and structural integrity than glycerolized skin. However, there was no significant difference among these groups in other histological criteria. There were no significant differences among the 4 groups in skin graft mechanical properties namely maximum load. In conclusion, Afp1m were found to be able to preserve the microstructure as well as the viability and function of the skin destined for skin transplantation when was kept at -4 °C for 72 h.
    Matched MeSH terms: Skin/cytology; Skin Transplantation*
  9. TermehYousefi A, Azhari S, Khajeh A, Hamidon MN, Tanaka H
    Mater Sci Eng C Mater Biol Appl, 2017 Aug 01;77:1098-1103.
    PMID: 28531983 DOI: 10.1016/j.msec.2017.04.040
    Haptic sensors are essential devices that facilitate human-like sensing systems such as implantable medical devices and humanoid robots. The availability of conducting thin films with haptic properties could lead to the development of tactile sensing systems that stretch reversibly, sense pressure (not just touch), and integrate with collapsible. In this study, a nanocomposite based hemispherical artificial fingertip fabricated to enhance the tactile sensing systems of humanoid robots. To validate the hypothesis, proposed method was used in the robot-like finger system to classify the ripe and unripe tomato by recording the metabolic growth of the tomato as a function of resistivity change during a controlled indention force. Prior to fabrication, a finite element modeling (FEM) was investigated for tomato to obtain the stress distribution and failure point of tomato by applying different external loads. Then, the extracted computational analysis information was utilized to design and fabricate nanocomposite based artificial fingertip to examine the maturity analysis of tomato. The obtained results demonstrate that the fabricated conformable and scalable artificial fingertip shows different electrical property for ripe and unripe tomato. The artificial fingertip is compatible with the development of brain-like systems for artificial skin by obtaining periodic response during an applied load.
    Matched MeSH terms: Skin, Artificial
  10. Khalik MZ, Hendriks K, Vermeulen JJ, Schilthuizen M
    Zookeys, 2018.
    PMID: 30026659 DOI: 10.3897/zookeys.773.24878
    The Bornean hydrocenids have so far been understudied compared to other non-pulmonate snails in this region. In the present study, we review a first group of minute land snail species belonging to the genus Georissa (Gastropoda, Hydrocenidae) from Malaysian Borneo. This group is restricted to the species with conspicuous scale-like sculpture on the shell. Based on materials from recent fieldwork, museums, and personal collections, Malaysian Borneo hydrocenids are more complex and diverse in shell characters than previously anticipated. Here, a molecular, conchological, and biogeographic study of this "scaly group" is presented. We recognise 13 species of which six are new to science, namely Georissa anyiensissp. n., Georissa muluensissp. n., Georissa bauensissp. n., Georissa silaburensissp. n., Georissa kinabatanganensissp. n., and Georissa sepulutensissp. n.
    Matched MeSH terms: Skin
  11. Apparau D, Apparau H, Mohamad I, Bhavaraju VMK
    AME Case Rep, 2018;2:4.
    PMID: 30264000 DOI: 10.21037/acr.2018.01.06
    Malignant melanoma (MM) of parotid gland is a rare condition. This pathology is often a result of secondary metastasis from primary lesions in the head and neck skin. A MM arising de novo in parotid gland is very rare. This malignant tumour is more prevalent in adults rather than children and it tends to have several distinct features. Treatment options are limited especially for an advanced lesion. Despite best treatments this condition carries a poor prognosis. This case details our experience in treating a child with MM of parotid gland without other primary cutaneous lesions.
    Matched MeSH terms: Skin Neoplasms
  12. Shalihin SE, Harun Z, Osman IF
    Malays Fam Physician, 2018;13(2):39-41.
    PMID: 30302184 MyJurnal
    Essential thrombocythemia is one of the myeloproliferative neoplasms. Palpable purpura is a rare manifestation that may delay diagnosis and treatment. We report a case of essential thrombocythemia in a 50-year-old man, who presented with recurrent thigh pain for the past one year with nonspecific localized purpura. His full blood count revealed isolated thrombocytosis of 880,000/µL with an impression of myeloproliferative disorder from peripheral blood film. He was referred urgently to the hematology team, which proceeded with a venesection. His condition improved with hydroxyurea. This was a rare case of chronic presentation of myeloproliferative neoplasm detected at a primary care clinic.
    Matched MeSH terms: Skin
  13. Lee SW, Loo CH, Tan WC
    Med J Malaysia, 2018 10;73(5):338-339.
    PMID: 30350820 MyJurnal
    Confluent and reticulated papillomatosis (CRP) was first described in 1927 by Gougerot and further characterised by Carteud.1 It is relatively rare, and the exact pathophysiology was not well known. Over the years, multiple treatment modalities were proposed. We report our experience with three cases of CRP which showed complete clearance with tetracycline group of antibiotics.
    Matched MeSH terms: Skin Neoplasms
  14. Nair HKR
    J Wound Care, 2018 Sep 01;27(Sup9a):S12-S19.
    PMID: 30207849 DOI: 10.12968/jowc.2018.27.Sup9a.S12
    OBJECTIVE: The primary aim was to determine the productivity increase using digital imagery for better documentation and analysis. A case series was done in a specialised care centre with patients managed with advanced dressings and using state-of-the-art smartphone technology for documentation to save costs and time.

    METHOD: Wounds were cleansed and debrided before using the application to photograph, document, measure and analyse the wounds. The smartphone app was oriented parallel to the plane of the wound, where possible, to obtain accurate measurements. A longitudinal study report was generated for each wound and showed the progress of the wound healing until the wound was closed.

    RESULTS: A sample size of 60 patients consisting of wounds from different locations, and a total of 203 measurements and analyses were conducted over a period of seven months. The wound monitoring app proved to be effective for wound monitoring and required less than two hours' training. A report summary of wounds recorded could also be generated automatically through the dashboard. All 60 patients' cases were automatically recorded, measured and presented into reports for use in clinical analysis. There was a significant time savings (27 hours per day for a specialised care centre with 10 nurses) increase over manual wound documentation and measuring methods.

    CONCLUSION: The app provided a non-contact, easy to use, reliable and accurate smart wound management solution for clinicians and physicians to track wound healing in patients. The app could also be used by patients and caregivers for home monitoring of their wounds.

    Matched MeSH terms: Skin Ulcer/economics; Skin Ulcer/pathology*; Skin Ulcer/rehabilitation
  15. Polunin I
    Nature, 1951;167:442.
    LABOURERS in factories in South Malaya who cut up pineapples by hand for canning invariably show an abnormality of those parts of the body which are exposed to slight pressure and pineapple juice, notably the palmar surfaces of the fingertips and the periphery of the palms. At the beginning of the canning season, the left hand, which comes more into contact with the fruit than the knife-holding hand, becomes sore and small superficial raw areas on the fingertips are often seen. Within several days, however, these heal, and the skin ceases to be sore. The labourers state that this tolerance to the pineapple juice is due to the development of an abnormality of the skin, which in the affected area becomes bluish-white and so smooth that fingerprints may be completely lost. Deep cracks are sometimes seen in the region of the skin creases. These often stay raw and bleeding for a long time, and show no clinical signs of infection, presumably because of removal of dead tissues by enzymatic action.
    Matched MeSH terms: Skin Diseases
  16. Norfifah Bachok, Anuar Ishak
    Sains Malaysiana, 2011;40:1297-1300.
    This paper presents a numerical analysis of a stagnation-point flow towards a nonlinearly stretching/shrinking sheet immersed in a viscous fluid. The stretching/shrinking velocity and the external flow velocity impinges normal to the stretching/shrinking sheet are assumed to be in the form U ~ xm, where m is a constant and x is the distance from the stagnation point. The governing partial differential equations are converted into ordinary ones by a similarity transformation, before being solved numerically. The variations of the skin friction coefficient and the heat transfer rate at the surface with the governing parameters are graphed and tabulated. Different from a stretching sheet, it is found that the solutions for a shrinking sheet are non-unique for m > 1/3.
    Matched MeSH terms: Skin
  17. Ibrahim N, Sakinah Z, Abdul Ghani Z, Ibrahim M
    Cureus, 2019 Mar 27;11(3):e4335.
    PMID: 31187000 DOI: 10.7759/cureus.4335
    Choroidal melanoma is an uncommon malignant melanoma among non-Caucasians. We report here a case of a high myope patient who presented with symptoms of acute retinal detachment, which had been diagnosed as possible rhegmatogenous retinal detachment from the initial assessment. A detailed vitreoretinal evaluation revealed a glimpse of an obscured intraocular mass underneath the detached retina, which later proved to be a choroidal melanoma. This is an unexpected cause of retinal detachment in a myopic eye. Furthermore, the rare nature of choroidal melanoma in this particular region of the world makes this an ignored diagnosis at presentation.
    Matched MeSH terms: Skin Neoplasms
  18. Leung AKC, Barankin B, Leong KF
    Curr Pediatr Rev, 2020;16(4):265-276.
    PMID: 32384035 DOI: 10.2174/1573396316666200508104708
    BACKGROUND: Henoch-Schönlein purpura (HSP) is an IgA-mediated systemic smallvessel vasculitis with a predilection for the skin, gastrointestinal tract, joints, and kidneys. It is the most common form of systemic vasculitis in children.

    OBJECTIVE: The study aimed to familiarize physicians with the etiopathogenesis, clinical manifestations, evaluation, and management of children with Henoch-Schönlein purpura.

    METHODS: A PubMed search was conducted in January 2020 in Clinical Queries using the key terms "Henoch-Schönlein purpura" OR "IgA vasculitis" OR "anaphylactoid purpura". The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews published within the past 10 years. Only papers published in the English literature were included in this review. This paper is based on, but not limited to, the search results.

    RESULTS: Globally, the incidence of HSP is 10 to 20 cases per 100, 000 children per year. Approximately 90% of cases occur in children between 2 and 10 years of age, with a peak incidence at 4 to 7 years. The diagnosis should be based on the finding of palpable purpura in the presence of at least one of the following criteria, namely, diffuse abdominal pain, arthritis or arthralgia, renal involvement (hematuria and/or proteinuria), and a biopsy showing predominant IgA deposition. Most cases are self-limited. The average duration of the disease is 4 weeks. Long-term complications are rare and include persistent hypertension and end-stage kidney disease. Therapy consists of general and supportive measures as well as treatment of the sequelae of the vasculitis. Current evidence does not support the universal treatment of HSP patients with corticosteroids. Oral corticosteroids may be considered for HSP patients with severe gastrointestinal pain and gastrointestinal hemorrhage.

    CONCLUSION: Most cases of HSP have an excellent outcome, with renal involvement being the most important prognostic factor in determining morbidity and mortality. Unfortunately, early steroid treatment does not reduce the incidence and severity of nephropathy in children with HSP. In HSP children who have severe nephritis or renal involvement with proteinuria of greater than 3 months, an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker should be considered in addition to corticosteroids to prevent and/or limit secondary glomerular injury.

    Matched MeSH terms: Skin
  19. Sio YY, Pang SL, Say YH, Teh KF, Wong YR, Shah SMR, et al.
    Mycopathologia, 2021 Oct;186(5):583-588.
    PMID: 34258653 DOI: 10.1007/s11046-021-00532-6
    Fungal spores and conidia are the major components of total airspora in the tropical Asia environment, and their sensitization patterns are often associated with allergic diseases such as asthma, allergic rhinitis (AR), and atopic dermatitis. Hence, we recruited a cross-sectional cohort of 9223 Singapore/Malaysia Chinese adults and assessed their sensitization against Curvularia lunata allergen using the skin prick test approach. A subset of this cohort (n = 254) was also screened for specific Immunoglobulin E (sIgE) titers against a panel of 11 fungal allergens. We found significant association of Curvularia lunata sensitization with the risk of asthma (OR = 1.66, 95% CI: 1.17-2.33; p = 0.00391) and AR (OR = 1.69, 95% CI: 1.18-2.41; p = 0.00396). Among asthmatic patients (n = 1680), Curvularia lunata sensitization also increased frequencies of wheezing symptoms (OR = 1.81, 95% CI: 1.05-2.96; p = 0.0239), general practitioner/specialist visits (OR = 2.37, 95% CI: 1.13-4.61; p = 0.0157), and other asthma-related exacerbation events (OR = 2.14, 95% CI: 1.04-4.10; p = 0.0289). In our serum cohort, sensitization to Aspergillus spp. was the most common fungal sensitization, with 23.6% (n = 60) had a class 3 and above sensitization (positive sensitization; sIgE titers of > 3.5 kU/L) against this allergen. Increasing sIgE titer against Aspergillus spp. was also correlated with increased AR risk and AR-related symptoms. In conclusion, our findings emphasize an important role of fungal sensitization in the manifestations of asthma and AR in the Southeast Asian Chinese population.
    Matched MeSH terms: Skin Tests
  20. Jing W
    J Dermatol, 2000 Apr;27(4):225-32.
    PMID: 10824485
    A retrospective analysis of 182 HIV positive Malaysians was done in two centers, the University Hospital Kuala Lumpur (UHKL) and the General Hospital Kuala Lumpur (GHKL) from March 1997 to February 1998. Demographic and clinical data were analyzed. The analysis showed that 130 out of 182 patients had mucocutaneous disorders (71.4%). In the study there were 125 males (96.2%) and 5 females (3.8%). The majority of the patients were in the age group from 20 to 50 years. The patients who presented with mucocutaneous disease also had low CD4+ T lymphocyte counts, and most of them had AIDS defining illnesses. The number of cases with generalized hyperpigmentation was very high (35.7%), followed by papular eruptions (29.1%) and xerosis (27.5%). Seborrheic dermatitis was seen in 19.2% of the cases and psoriasis in 7.7%. The most common infections were oral candida 35.7%, tinea corporis and onychomycosis 9.9%, and herpes infection 4.3%. However, mucocutaneous manifestations of Kaposi's sarcoma were rare. The results suggested that mucocutaneous findings are useful clinical predictors of HIV infection or a sign of the presence of advanced HIV infection.
    Matched MeSH terms: Skin Diseases/etiology; Skin Diseases/epidemiology*; Skin Diseases/pathology
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