Displaying publications 161 - 180 of 280 in total

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  1. Akbari A, Mohammadian E, Alavi Fazel SA, Shanbedi M, Bahreini M, Heidari M, et al.
    ACS Omega, 2019 Nov 19;4(21):19183-19192.
    PMID: 31763542 DOI: 10.1021/acsomega.9b02474
    An increase of nucleate pool boiling with the use of different fluid properties has received much attention. In particular, the presence of nanostructures in fluids to enhance boiling was given special consideration. This study compares the effects of graphene nanoplatelet (GNP), functionalized GNP with polyethylene glycol (PEG), and multiwalled carbon nanotube (CNT) nanofluids on the pool boiling heat transfer coefficient and the critical heat flux (CHF). Our findings showed that at the same concentration, CHF for functionalized GNP with PEG (GNP-PEG)/deionized water (DW) nanofluids was higher in comparison with GNP- and CNT-based nanofluids. The CHF of the GNP/DW nanofluids was also higher than that of CNT/DW nanofluids. The CHF of GNP-PEG was 72% greater than that of DW at the concentration of 0.1 wt %. There is good agreement between measured critical heat fluxes and the Kandlikar correlation. In addition, the current results proved that the GNP-PEG/DW nanofluids are highly stable over 3 months at a concentration of 0.1 wt %.
    Matched MeSH terms: Nanotubes, Carbon
  2. Toussi SM, Fakhru’L-Razi A, Luqman Chuah A, Suraya A
    Single-walled carbon nanotubes (SWCNTs) were synthesized by catalytic chemical vapor deposition (CCVD) of ethanol (C2H5OH) over Fe-Mo-MgO catalyst by using argon as a carrier gas. The reaction conditions are important factors that influence the yield and quality of carbon nanotubes. The effects of temperature and flow rate of carrier gas were investigated to increase the yield of carbon nanotubes. The synthesized carbon nanotubes were characterized by scanning electron microscopy, transmission electron microscopy, X-Ray diffraction and thermo-gravimetric analysis. The results showed that the growth of carbon nanotubes was effectively influenced by the reaction ambience and the synthesis condition. The temperature and flow rate of carrier gas played a key role in the yield and quality of synthesized CNTs. The estimated yield of synthesized carbon nanotubes was almost over 70%.
    Matched MeSH terms: Nanotubes, Carbon
  3. Khan A, Karimov KS, Zubair Armad, Khaulah Sulaiman, Shah M, Moiz S
    Sains Malaysiana, 2014;43:903-908.
    In this paper, fabrication and investigation of organic pressure sensor based on AlICIVT-VO 2(3j7)ICu composite is reported. The active layer of the composite was deposited by drop-casting of the blend CN'T-VO 2 (3fl) on a glass substrate (with prefabricated copper (Cu) electrode). The thin film of the blend consists of carbon nanotube CNT, (2.55 wt. %) and vanadium oxide (VO 2 (3fl)) micropowder, (3 wt. %) in benzol (1 mL). The thickness of the composite was in the range of 20-40 ,um. It was found that the fabricated sensor was sensitive to pressure and showed good repeatability. The decrease in resistance of the sensor was observed by increasing the external uniaxial pressure up to 50 kNm-2 . The experimentally obtained results were compared with the simulated results and showed reasonable agreement with each other.
    Matched MeSH terms: Nanotubes, Carbon
  4. Jamal M. A. Alsharef, Mohd Raihan Taha, Ramez A. Al-Mansob, Tanveer Ahmed Khan, Mohd Raihan Taha
    Sains Malaysiana, 2018;47:195-205.
    In this study, the performance of two types of nanocarbons (NCs), namely carbon nanotubes (CNTs) and carbon nanofibers (CNFs), on the three-dimensional shrinkage and swelling properties of three clayey soils were investigated. The specimens of soil mixed with clay with bentonite contents of 0, 10 and 20% by weight of dry soil. NC contents of 0.05, 0.075, 0.10 and 0.20% were chosen to investigate the influence of different NC types, CNTs and CNFs. All soil specimens were compacted under maximum dry unit weight and optimum water content conditions by using standard compaction tests. The physical and mechanical characteristics of the reinforced samples were then determined. These included the desiccation cracking area, used to determine the crack intensity factor (CIF), as well as the shrinkage and swelling. The CIF for the soil specimens without NCs were higher than the soil specimens with NC additives. These results show that NCs decrease the development of desiccation cracks on the surface of compacted samples. The shrinkage and swelling tests showed that the rate of volume changing of the compacted soil specimens reduced with the increasing of NCs.
    Matched MeSH terms: Nanotubes, Carbon
  5. Noor Kamalia Abd Hamed, Noor Sakinah Khalid, Fatin Izyani Mohd Fazli, Muhammad Luqman Mohd Napi, Nafarizal Nayan, Mohd Khairul Ahmad
    Sains Malaysiana, 2016;45:1669-1673.
    Titanium dioxide (TiO2
    ) with various morphologies has been successfully synthesized by a simple hydrothermal method
    at 150o
    C for 10 h using titanium butoxide (TBOT) as a precursor, deionized (DI) water and hydrochloric acid (HCl) on
    a fluorine-doped tin oxide (FTO) substrate. The influences of HCl volume on structural and morphological properties
    of TiO2
    have been studied using x-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM),
    respectively. The result showed that several morphologies such as microsphere, microrods, nanorods and nanoflowers
    were obtained by varying the volume of hydrochloric acid. The crystallinity of titanium dioxide enhanced with the
    increasing of hydrochloric acid volume.
    Matched MeSH terms: Nanotubes
  6. Hosseingholipourasl A, Hafizah Syed Ariffin S, Ahmadi MT, Rahimian Koloor SS, Petrů M, Hamzah A
    Sensors (Basel), 2020 Jan 08;20(2).
    PMID: 31936402 DOI: 10.3390/s20020357
    Recent advances in nanotechnology have revealed the superiority of nanocarbon species such as carbon nanotubes over other conventional materials for gas sensing applications. In this work, analytical modeling of the semiconducting zigzag carbon nanotube field-effect transistor (ZCNT-FET) based sensor for the detection of gas molecules is demonstrated. We propose new analytical models to strongly simulate and investigate the physical and electrical behavior of the ZCNT sensor in the presence of various gas molecules (CO2, H2O, and CH4). Therefore, we start with the modeling of the energy band structure by acquiring the new energy dispersion relation for the ZCNT and introducing the gas adsorption effects to the band structure model. Then, the electrical conductance of the ZCNT is modeled and formulated while the gas adsorption effect is considered in the conductance model. The band structure analysis indicates that, the semiconducting ZCNT experiences band gap variation after the adsorption of the gases. Furthermore, the bandgap variation influences the conductance of the ZCNT and the results exhibit increments of the ZCNT conductance in the presence of target gases while the minimum conductance shifted upward around the neutrality point. Besides, the I-V characteristics of the sensor are extracted from the conductance model and its variations after adsorption of different gas molecules are monitored and investigated. To verify the accuracy of the proposed models, the conductance model is compared with previous experimental and modeling data and a good consensus is observed. It can be concluded that the proposed analytical models can successfully be applied to predict sensor behavior against different gas molecules.
    Matched MeSH terms: Nanotubes, Carbon
  7. Gaaz TS, Sulong AB, Kadhum AAH, Nassir MH, Al-Amiery AA
    Materials (Basel), 2016 Jul 26;9(8).
    PMID: 28773741 DOI: 10.3390/ma9080620
    Halloysite (HNT) is treated with sulfuric acid and the physico-chemical properties of its morphology, surface activity, physical and chemical properties have been investigated when HNT is exposed to sulfuric acid with treatment periods of 1 h (H1), 3 h (H3), 8 h (H8), and 21 h (H21). The significance of this and similar work lies in the importance of using HNT as a functional material in nanocomposites. The chemical structure was characterized by Fourier transform infrared spectroscopy (FTIR). The spectrum demonstrates that the hydroxyl groups were active for grafting modification using sulfuric acid, promoting a promising potential use for halloysite in ceramic applications as filler for novel clay-polymer nanocomposites. From the X-ray diffraction (XRD) spectrum, it can be seen that the sulfuric acid breaks down the HNT crystal structure and alters it into amorphous silica. In addition, the FESEM images reveal that the sulfuric acid treatment dissolves the AlO₆ octahedral layers and induces the disintegration of SiO₄ tetrahedral layers, resulting in porous nanorods. The Bruncher-Emmett-Teller (BET) surface area and total pore volume of HNTs showed an increase. The reaction of the acid with both the outer and inner surfaces of the nanotubes causes the AlO₆ octahedral layers to dissolve, which leads to the breakdown and collapse of the tetrahedral layers of SiO₄. The multi-fold results presented in this paper serve as a guide for further HNT functional treatment for producing new and advanced nanocomposites.
    Matched MeSH terms: Nanotubes
  8. Nasir S, Hussein MZ, Zainal Z, Yusof NA
    Materials (Basel), 2018 Feb 13;11(2).
    PMID: 29438327 DOI: 10.3390/ma11020295
    Carbon in its single entity and various forms has been used in technology and human life for many centuries. Since prehistoric times, carbon-based materials such as graphite, charcoal and carbon black have been used as writing and drawing materials. In the past two and a half decades or so, conjugated carbon nanomaterials, especially carbon nanotubes, fullerenes, activated carbon and graphite have been used as energy materials due to their exclusive properties. Due to their outstanding chemical, mechanical, electrical and thermal properties, carbon nanostructures have recently found application in many diverse areas; including drug delivery, electronics, composite materials, sensors, field emission devices, energy storage and conversion, etc. Following the global energy outlook, it is forecasted that the world energy demand will double by 2050. This calls for a new and efficient means to double the energy supply in order to meet the challenges that forge ahead. Carbon nanomaterials are believed to be appropriate and promising (when used as energy materials) to cushion the threat. Consequently, the amazing properties of these materials and greatest potentials towards greener and environment friendly synthesis methods and industrial scale production of carbon nanostructured materials is undoubtedly necessary and can therefore be glimpsed as the focal point of many researchers in science and technology in the 21st century. This is based on the incredible future that lies ahead with these smart carbon-based materials. This review is determined to give a synopsis of new advances towards their synthesis, properties, and some applications as reported in the existing literatures.
    Matched MeSH terms: Nanotubes, Carbon
  9. Hayder Baqer Abdullah, Irmawati Ramli, Ismayadi Ismail, Nor Azah Yusof
    MyJurnal
    The synthesis of carbon nanotubes (CNTs) using a chemical vapour deposition (CVD) method requires the use of hydrocarbon as the carbon precursor. Among the commonly used hydrocarbons are methane and acetylene, which are both light gas-phase substances. Besides that, other carbon-rich sources, such as carbon monoxide and coal, have also been reportedly used. Nowadays, researches have also been conducted into utilising heavier hydrocarbons and petrochemical products for the production of CNTs, such as kerosene and diesel oil. Therefore, this article reviews the different kind of hydrocarbon sources for CNTs production using a CVD method. The method is used for it allows the decomposition of the carbon-rich source with the aid of a catalyst at a temperature in the range 600-1200°C. This synthesis technique gives an advantage as a high yield and high-quality CNTs can be produced at a relatively low cost process. As compared to other processes for CNTs production such as arc discharge and laser ablation, they may produce high quality CNTs but has a disadvantage for use as large scale synthesis routes.
    Matched MeSH terms: Nanotubes, Carbon
  10. TermehYousefi A, Bagheri S, Shahnazar S, Rahman MH, Kadri NA
    Mater Sci Eng C Mater Biol Appl, 2016 Feb;59:636-642.
    PMID: 26652417 DOI: 10.1016/j.msec.2015.10.041
    Carbon nanotubes (CNTs) are potentially ideal tips for atomic force microscopy (AFM) due to the robust mechanical properties, nanoscale diameter and also their ability to be functionalized by chemical and biological components at the tip ends. This contribution develops the idea of using CNTs as an AFM tip in computational analysis of the biological cells. The proposed software was ABAQUS 6.13 CAE/CEL provided by Dassault Systems, which is a powerful finite element (FE) tool to perform the numerical analysis and visualize the interactions between proposed tip and membrane of the cell. Finite element analysis employed for each section and displacement of the nodes located in the contact area was monitored by using an output database (ODB). Mooney-Rivlin hyperelastic model of the cell allows the simulation to obtain a new method for estimating the stiffness and spring constant of the cell. Stress and strain curve indicates the yield stress point which defines as a vertical stress and plan stress. Spring constant of the cell and the local stiffness was measured as well as the applied force of CNT-AFM tip on the contact area of the cell. This reliable integration of CNT-AFM tip process provides a new class of high performance nanoprobes for single biological cell analysis.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  11. Hajian R, Yusof NA, Faragi T, Shams N
    PLoS One, 2014;9(5):e96686.
    PMID: 24809346 DOI: 10.1371/journal.pone.0096686
    In this paper, the electrochemical behavior of myricetin on a gold nanoparticle/ethylenediamine/multi-walled carbon-nanotube modified glassy carbon electrode (AuNPs/en/MWCNTs/GCE) has been investigated. Myricetin effectively accumulated on the AuNPs/en/MWCNTs/GCE and caused a pair of irreversible redox peaks at around 0.408 V and 0.191 V (vs. Ag/AgCl) in 0.1 mol L-1 phosphate buffer solution (pH 3.5) for oxidation and reduction reactions respectively. The heights of the redox peaks were significantly higher on AuNPs/en/MWNTs/GCE compare with MWCNTs/GC and there was no peak on bare GC. The electron-transfer reaction for myricetin on the surface of electrochemical sensor was controlled by adsorption. Some parameters including pH, accumulation potential, accumulation time and scan rate have been optimized. Under the optimum conditions, anodic peak current was proportional to myricetin concentration in the dynamic range of 5.0×10-8 to 4.0×10-5 mol L-1 with the detection limit of 1.2×10-8 mol L-1. The proposed method was successfully used for the determination of myricetin content in tea and fruit juices.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  12. Basri S, Kamarudin SK, Daud WR, Yaakob Z, Kadhum AA
    ScientificWorldJournal, 2014;2014:547604.
    PMID: 24883406 DOI: 10.1155/2014/547604
    PtRu catalyst is a promising anodic catalyst for direct methanol fuel cells (DMFCs) but the slow reaction kinetics reduce the performance of DMFCs. Therefore, this study attempts to improve the performance of PtRu catalysts by adding nickel (Ni) and iron (Fe). Multiwalled carbon nanotubes (MWCNTs) are used to increase the active area of the catalyst and to improve the catalyst performance. Electrochemical analysis techniques, such as energy dispersive X-ray spectrometry (EDX), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and X-ray photoelectron spectroscopy (XPS), are used to characterize the kinetic parameters of the hybrid catalyst. Cyclic voltammetry (CV) is used to investigate the effects of adding Fe and Ni to the catalyst on the reaction kinetics. Additionally, chronoamperometry (CA) tests were conducted to study the long-term performance of the catalyst for catalyzing the methanol oxidation reaction (MOR). The binding energies of the reactants and products are compared to determine the kinetics and potential surface energy for methanol oxidation. The FESEM analysis results indicate that well-dispersed nanoscale (2-5 nm) PtRu particles are formed on the MWCNTs. Finally, PtRuFeNi/MWCNT improves the reaction kinetics of anode catalysts for DMFCs and obtains a mass current of 31 A g(-1) catalyst.
    Matched MeSH terms: Nanotubes, Carbon/chemistry
  13. Soheilmoghaddam M, Wahit MU
    Int J Biol Macromol, 2013 Jul;58:133-9.
    PMID: 23567285 DOI: 10.1016/j.ijbiomac.2013.03.066
    In this study, novel nanocomposite films based on regenerated cellulose/halloysite nanotube (RC/HNT) have been prepared using an environmentally friendly ionic liquid 1-butyl-3-methylimidazolium chloride (BMIMCl) through a simple green method. The structural, morphological, thermal and mechanical properties of the RC/HNT nanocomposites were investigated using X-ray diffraction (XRD), Fourier transform infrared (FTIR), field emission scanning electron microscopy (FESEM), thermal analysis and tensile strength measurements. The results obtained revealed interactions between the halloysite nanotubes and regenerated cellulose matrix. The thermal stability and mechanical properties of the nanocomposite films, compared with pure regenerated cellulose film, were significantly improved When the halloysite nanotube (HNT) loading was only 2 wt.%, the 20% weight loss temperature (T20) increased 20°C. The Young's modulus increased from 1.8 to 4.1 GPa, while tensile strength increased from 35.30 to 60.50 MPa when 8 wt.% halloysite nanotube (HNT) was incorporated, interestingly without loss of ductility. The nanocomposite films exhibited improved oxygen barrier properties and water absorption resistance compared to regenerated cellulose.
    Matched MeSH terms: Nanotubes/chemistry*
  14. Pang YL, Abdullah AZ
    J Hazard Mater, 2012 Oct 15;235-236:326-35.
    PMID: 22939090 DOI: 10.1016/j.jhazmat.2012.08.008
    Fe-doped titanium dioxide (TiO(2)) nanotubes were prepared using sol-gel followed by hydrothermal methods and characterized using various methods. The sonocatalytic activity was evaluated based on oxidation of Rhodamine B under ultrasonic irradiation. Iron ions (Fe(3+)) might incorporate into the lattice and intercalated in the interlayer spaces of TiO(2) nanotubes. The catalysts showed narrower band gap energies, higher specific surface areas, more active surface oxygen vacancies and significantly improved sonocatalytic activity. The optimum Fe doping at Fe:Ti=0.005 showed the highest sonocatalytic activity and exceeded that of un-doped TiO(2) nanotubes by a factor of 2.3 times. It was believed that Fe(3+) doping induced the formation of new states close to the valence band and conduction bands and accelerated the separation of charge carriers. Leached Fe(3+) could catalyze Fenton-like reaction and led to an increase in the hydroxyl radical (OH) generation. Fe-doped TiO(2) nanotubes could retain high degradation efficiency even after being reused for 4 cycles with minimal loss of Fe from the surface of the catalyst.
    Matched MeSH terms: Nanotubes/chemistry*
  15. Tehrani RM, Ab Ghani S
    Biosens Bioelectron, 2012 Oct-Dec;38(1):278-83.
    PMID: 22742810 DOI: 10.1016/j.bios.2012.05.044
    A non-enzymatic glucose sensor of multi-walled carbon nanotube-ruthenium oxide/composite paste electrode (MWCNT-RuO(2)/CPE) was developed. The electrode was characterized by using XRD, SEM, TEM and EIS. Meanwhile, cyclic voltammetry and amperometry were used to check on the performances of the MWCNT-RuO(2)/CPE towards glucose. The proposed electrode has displayed a synergistic effect of RuO(2) and MWCNT on the electrocatalytic oxidation of glucose in 3M NaOH. This was possible via the formation of transitions of two redox pairs, viz. Ru(VI)/Ru(IV) and Ru(VII)/Ru(VI). A linear range of 0.5-50mM glucose and a limit of detection of 33 μM glucose (S/N=3) were observed. There was no significant interference observable from the traditional interferences, viz. ascorbic acid and uric acid. Indeed, results so obtained have indicated that the developed MWCNT-RuO(2)/CPE would pave the way for a better future to glucose sensor development as its fabrication was without the use of any enzyme.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  16. Ghadimi H, Tehrani RM, Ali AS, Mohamed N, Ab Ghani S
    Anal Chim Acta, 2013 Feb 26;765:70-6.
    PMID: 23410628 DOI: 10.1016/j.aca.2012.12.039
    A novel glassy carbon electrode (GCE) modified with a composite film of poly (4-vinylpyridine) (P4VP) and multiwalled carbon nanotubes (P4VP/MWCNT GCE) was used for the voltammetric determination of paracetamol (PCT). This novel electrode displayed a combined effect of P4VP and MWCNT on the electro-oxidation of PCT in a solution of phosphate buffer at pH 7. Hence, conducting properties of P4VP along with the remarkable physical properties of MWCNTs might have combined effects in enhancing the kinetics of PCT oxidation. The P4VP/MWCNT GCE has also demonstrated excellent electrochemical activity toward PCT oxidation compared to that with bare GCE and MWCNT GCE. The anodic peak currents of PCT on the P4VP/MWCNT GCE were about 300 fold higher than that of the non-modified electrodes. By applying differential pulse voltammetry technique under optimized experimental conditions, a good linear ratio of oxidation peak currents and concentrations of PCT over the range of 0.02-450 μM with a limit of detection of 1.69 nM were achieved. This novel electrode was stable for more than 60 days and reproducible responses were obtained at 99% of the initial current of PCT without any influence of physiologically common interferences such as ascorbic acid and uric acid. The application of this electrode to determine PCT in tablets and urine samples was proposed.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  17. Gorain B, Choudhury H, Pandey M, Kesharwani P, Abeer MM, Tekade RK, et al.
    Biomed Pharmacother, 2018 Aug;104:496-508.
    PMID: 29800914 DOI: 10.1016/j.biopha.2018.05.066
    Myocardial infarction (cardiac tissue death) is among the most prevalent causes of death among the cardiac patients due to the inability of self-repair in cardiac tissues. Myocardial tissue engineering is regarded as one of the most realistic strategies for repairing damaged cardiac tissue. However, hindrance in transduction of electric signals across the cardiomyocytes due to insulating properties of polymeric materials worsens the clinical viability of myocardial tissue engineering. Aligned and conductive scaffolds based on Carbon nanotubes (CNT) have gained remarkable recognition due to their exceptional attributes which provide synthetic but viable microenvironment for regeneration of engineered cardiomyocytes. This review presents an overview and critical analysis of pharmaceutical implications and therapeutic feasibility of CNT based scaffolds in improving the cardiac tissue regeneration and functionality. The expository analysis of the available evidence revealed that inclusion of single- or multi-walled CNT into fibrous, polymeric, and elastomeric scaffolds results in significant improvement in electrical stimulation and signal transduction through cardiomyocytes. Moreover, incorporation of CNT in engineering scaffolds showed a greater potential of augmenting cardiomyocyte proliferation, differentiation, and maturation and has improved synchronous beating of cardiomyocytes. Despite promising ability of CNT in promoting functionality of cardiomyocytes, their presence in scaffolds resulted in substantial improvement in mechanical properties and structural integrity. Conclusively, this review provides new insight into the remarkable potential of CNT aligned scaffolds in improving the functionality of engineered cardiac tissue and signifies their feasibility in cardiac tissue regenerative medicines and stem cell therapy.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  18. Fatin MF, Rahim Ruslinda A, Gopinath SCB, Arshad MKM
    Int J Biol Macromol, 2019 Mar 15;125:414-422.
    PMID: 30529550 DOI: 10.1016/j.ijbiomac.2018.12.066
    Interaction between split RNA aptamer and the clinically important target, HIV-1 Tat was investigated on a biosensing surface transduced by functionally choreographed multiwall carbon nanotubes (MWCNTs). Acid oxidation was performed to functionalize MWCNTs with carboxyl functional groups. X-ray photoelectron spectroscopy analysis had profound ~2.91% increment in overall oxygen group and ~1% increment was noticed with a specific carboxyl content owing to CO and OCO bonding. The interaction between split RNA aptamer and HIV-1 Tat protein was quantified by electrical measurements with the current signal (Ids) over a gate voltage (Vgs). Initially, 34.4 mV gate voltage shift was observed by the immobilization of aptamer on MWCNT. With aptamer and HIV-1 Tat interaction, the current flow was decreased with the concomitant gate voltage shift of 23.5 mV. The attainment of sensitivity with split aptamer and HIV-1 Tat interaction on the fabricated device was 600 pM. To ensure the genuine interaction of aptamer with HIV-1 Tat, other HIV-1 proteins, Nef and p24 were interacted with aptamer and they displayed the negligible interferences with gate voltage shift of 3.5 mV and 5.7 mV, which shows 4 and 2.5 folds lesser than HIV-1 Tat interaction, respectively.
    Matched MeSH terms: Nanotubes, Carbon/chemistry*
  19. Ong LC, Chung FF, Tan YF, Leong CO
    Arch Toxicol, 2016 Jan;90(1):103-18.
    PMID: 25273022 DOI: 10.1007/s00204-014-1376-6
    Carbon nanotubes (CNTs) are an important class of nanomaterials, which have numerous novel properties that make them useful in technology and industry. Generally, there are two types of CNTs: single-walled nanotubes (SWNTs) and multi-walled nanotubes. SWNTs, in particular, possess unique electrical, mechanical, and thermal properties, allowing for a wide range of applications in various fields, including the electronic, computer, aerospace, and biomedical industries. However, the use of SWNTs has come under scrutiny, not only due to their peculiar nanotoxicological profile, but also due to the forecasted increase in SWNT production in the near future. As such, the risk of human exposure is likely to be increased substantially. Yet, our understanding of the toxicological risk of SWNTs in human biology remains limited. This review seeks to examine representative data on the nanotoxicity of SWNTs by first considering how SWNTs are absorbed, distributed, accumulated and excreted in a biological system, and how SWNTs induce organ-specific toxicity in the body. The contradictory findings of numerous studies with regards to the potential hazards of SWNT exposure are discussed in this review. The possible mechanisms and molecular pathways associated with SWNT nanotoxicity in target organs and specific cell types are presented. We hope that this review will stimulate further research into the fundamental aspects of CNTs, especially the biological interactions which arise due to the unique intrinsic characteristics of CNTs.
    Matched MeSH terms: Nanotubes, Carbon/toxicity*
  20. Mohamad NR, Buang NA, Mahat NA, Lok YY, Huyop F, Aboul-Enein HY, et al.
    Enzyme Microb Technol, 2015 May;72:49-55.
    PMID: 25837507 DOI: 10.1016/j.enzmictec.2015.02.007
    In view of several disadvantages as well as adverse effects associated with the use of chemical processes for producing esters, alternative techniques such as the utilization of enzymes on multi-walled carbon nanotubes (MWCNTs), have been suggested. In this study, the oxidative MWCNTs prepared using a mixture of HNO3 and H2SO4 (1:3 v/v) were used as a supportive material for the immobilization of Candida rugosa lipase (CRL) through physical adsorption process. The resulting CRL-MWCNTs biocatalysts were utilized for synthesizing geranyl propionate, an important ester for flavoring agent as well as in fragrances. Enzymatic esterification of geraniol with propionic acid was carried out using heptane as a solvent and the efficiency of CRL-MWCNTs as a biocatalyst was compared with the free CRL, considering the incubation time, temperature, molar ratio of acid:alcohol, presence of desiccant as well as its reusability. It was found that the CRL-MWCNTs resulted in a 2-fold improvement in the percentage of conversion of geranyl propionate when compared with the free CRL, demonstrating the highest yield of geranyl propionate at 6h at 55°C, molar ratio acid: alcohol of 1:5 and with the presence of 1.0g desiccant. It was evident that the CRL-MWCNTs biocatalyst could be reused for up to 6 times before a 50% reduction in catalytic efficiency was observed. Hence, it appears that the facile physical adsorption of CRL onto F-MWCNTs has improved the activity and stability of CRL as well as served as an alternative method for the synthesis of geranyl propionate.
    Matched MeSH terms: Nanotubes, Carbon/ultrastructure
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