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Cartilage regeneration by chondrogenic induced adult stem cells in osteoarthritic sheep model

Ude CC 1 , Sulaiman SB 2 , Min-Hwei N 2 , Hui-Cheng C 3 , Ahmad J 4 , Yahaya NM 4 Show all authors , Saim AB 5 , Idrus RB 1

Affiliations 

  • 1 Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Selangor, Malaysia; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Selangor, Malaysia
  • 2 Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Selangor, Malaysia
  • 3 Department of Clinical Veterinary, Faculty of Veterinary Medicine Universiti Putra Malaysia, Serdang, Selangor, Malaysia
  • 4 Department of Orthopedic & Traumatology, Universiti Kebangsaan Malaysia Medical Center, Cheras, Selangor, Malaysia
  • 5 Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Selangor, Malaysia; ENT Consultant Clinic, Ampang Putri Specialist Hospital, Ampang, Selangor, Malaysia
PLoS One, 2014;9(6):e98770.
PMID: 24911365 DOI: 10.1371/journal.pone.0098770

Abstract

In this study, Adipose stem cells (ADSC) and bone marrow stem cells (BMSC), multipotent adult cells with the potentials for cartilage regenerations were induced to chondrogenic lineage and used for cartilage regenerations in surgically induced osteoarthritis in sheep model.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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