Chemotherapeutic potentials of the stem bark of Balanite aegyptiaca (L.) Delile: an antiangiogenic, antitumor and antioxidant agent

Hassan LE 1 , Dahham SS 1 , Saghir SA 1 , Mohammed AM 2 , Eltayeb NM 3 , Majid AM 4 Show all authors , Majid AS 5

Affiliations 

  • 1 EMAN Research and Testing Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia
  • 2 Department of Chemistry, Alzaiem Alazhari University, P.O Box 1432, Khartoum North, 13311, Sudan
  • 3 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, 11800, Universiti Sains Malaysia, Penang, Malaysia
  • 4 ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research Australian National University, Canberra, Malaysia
  • 5 Department of Pharmacology, Quest International University, Perak, Malaysia. aman.shah@qiup.edu.my
BMC Complement Altern Med, 2016 Oct 19;16(1):396.
PMID: 27760539

Abstract

Balanite aegyptiaca (L.) Delile, is a plant with extensive medicinal properties. Its stem bark is traditionally known for its spasmolytic and antiepileptic properties and used to treat yellow fever, jaundice and syphilis. Angiogenesis (sprouting of new blood vessels) is crucial for tumor growth and metastasis. The goal of this study is investigate the antiangiogenic, cytotoxicity and antioxidant activity as well as antitumor in vivo properties of B. aegyptiaca stem bark extracts.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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