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  1. O. Wan-Norafikah, CoRe , H. W., Azahari, A. H., K. Kamal-Hidayat, Lee , H. L., I. Saleh
    MyJurnal
    A preliminary field study was undertaken to evaluate the efficacy of a mosquito trap; Mosquito Killing System (MKS) in
    capturing mosquitoes and other insects. MKS has an automatic activation by the use of a photocell. It is also supplemented
    with carbon dioxide and heat as attractants for mosquitoes and other insects. Three units of MKS were employed at three
    different locations within two study sites for ten days. The mosquitoes and other insects that were trapped in MKS were
    collected and morphologically identified daily in the laboratory. A total of 1,928 mosquitoes and other insects were
    trapped in all units of MKS. High numbers of mosquitoes (93.05%), particularly Aedes sp. and Culex sp. were captured
    from MKS. Among these, Culex quinquefasciatus (91.81%) was most abundant species collected. Only 0.84% of Aedes
    aegypti and Aedes albopictus trapped in MKS. Female mosquitoes (83.44%) were found to be more attracted to MKS
    compared to male mosquitoes of various species. These findings illustrated the potency of MKS utilization in surveillance
    and control activities of Cx. quinquefasciatus; a nuisance mosquito and also potential vector of urban brancroftian
    filariasis in Malaysia.
    Matched MeSH terms: Malaysia
  2. Muhammad Hibatullah Romli, Mackenzie, Lynette, Tan, Maw Pin, Lovarini, Meryl, Clemson, Lindy
    MyJurnal
    Introduction: Home visits are complex processes for clients and occupational therapists. Despite the benefits of home
    visits, the numbers of home visits being conducted are decreasing in international settings due to service constraints
    or client reluctance. Published international studies may not be applicable to Malaysia due to cultural and geodemographic
    differences relating to the home context. This study aimed to explore the experience of occupational
    therapists in Malaysia in conducting home visits. Materials and Methods: A focus group discussion was conducted
    with seven occupational therapists in one teaching hospital in Kuala Lumpur. The group session was audio-recorded,
    transcribed, summarised and analysed using thematic analysis. Results: Themes developed were: i) client factors
    inhibiting effective service provision, ii) uninformed policies and guidelines, and iii) professional identity and
    growth. Conclusions: Our study has revealed major challenges for Malaysian occupational therapists with regards
    to conducting home visits. Future studies should now evaluate factors underlying reluctance to participate in home
    visits and effective strategies to overcome these difficulties.
    Matched MeSH terms: Malaysia
  3. Gibbs S, Hundt PJ, Nelson A, Egan JP, Tongnunui P, Simons AM
    Zootaxa, 2018 Jan 03;4369(2):270-280.
    PMID: 29689891 DOI: 10.11646/zootaxa.4369.2.7
    The combtooth blenny (Blenniidae) genus Omobranchus contains small, cryptobenthic fishes common to nearshore habitats throughout the Indo-West Pacific. Recent molecular systematic studies have resolved Omobranchus as monophyletic but little research has been done to resolve species-level relationships. Herein, phylogenetic analyses of one mitochondrial (CO1) and four nuclear (ENC1, myh6, sreb2, and tbr1) genes provide evidence for the monophyly of Omobranchus and support for the elongatus and banditus species group. Sampling of multiple individuals from widespread species (O. ferox, O. punctatus, and O. elongatus) suggested that the Thai-Malay Peninsula is a phylogeographic break that may be a historic barrier to gene flow. Additionally, common meristics and other morphological characters are used to describe an early life history stage of O. ferox and O. punctatus.
    Matched MeSH terms: Malaysia
  4. Mohamad Marzuki MF, Yaacob NA, Yaacob NM
    JMIR Hum Factors, 2018 May 14;5(2):e10308.
    PMID: 29759955 DOI: 10.2196/10308
    BACKGROUND: A mobile app is a programmed system designed to be used by a target user on a mobile device. The usability of such a system refers not only to the extent to which product can be used to achieve the task that it was designed for, but also its effectiveness and efficiency, as well as user satisfaction. The System Usability Scale is one of the most commonly used questionnaires used to assess the usability of a system. The original 10-item version of System Usability Scale was developed in English and thus needs to be adapted into local languages to assess the usability of a mobile apps developed in other languages.

    OBJECTIVE: The aim of this study is to translate and validate (with cross-cultural adaptation) the English System Usability Scale questionnaire into Malay, the main language spoken in Malaysia. The development of a translated version will allow the usability of mobile apps to be assessed in Malay.

    METHODS: Forward and backward translation of the questionnaire was conducted by groups of Malay native speakers who spoke English as their second language. The final version was obtained after reconciliation and cross-cultural adaptation. The content of the Malay System Usability Scale questionnaire for mobile apps was validated by 10 experts in mobile app development. The efficacy of the questionnaire was further probed by testing the face validity on 10 mobile phone users, followed by reliability testing involving 54 mobile phone users.

    RESULTS: The content validity index was determined to be 0.91, indicating good relevancy of the 10 items used to assess the usability of a mobile app. Calculation of the face validity index resulted in a value of 0.94, therefore indicating that the questionnaire was easily understood by the users. Reliability testing showed a Cronbach alpha value of .85 (95% CI 0.79-0.91) indicating that the translated System Usability Scale questionnaire is a reliable tool for the assessment of usability of a mobile app.

    CONCLUSIONS: The Malay System Usability Scale questionnaire is a valid and reliable tool to assess the usability of mobile app in Malaysia.

    Matched MeSH terms: Malaysia
  5. Irni Mohd Yasin, Narazah Mohd Yusoff, Afifah Hassan, Muhammad Masrin Md. Zahrin
    MyJurnal
    Haemolytic Disease of Foetus and Newborn (HDFN) and Haemolytic Transfusion Reaction (HTR) may occur due to antibodies against Kidd antigen. In Malaysia, the prevalence of RBC alloimmunization due to Kidd antibody for cases of HDFN and HTR have been reported [1-2] however there is insufficient data in Hospital Umum Sarawak (HUS).The aim of this study is to determine whether Kidd alloimmunization causes HDFN and HTR. Indirectly categorize Kidd phenotype blood in regular blood donors.
    Matched MeSH terms: Malaysia
  6. Octavianti, F., Jaswir, I.
    MyJurnal
    This paper discusses effects of metal toxicity and environment on health and followed by a study report on mineral and heavy metal contents of fish conducted in Malaysia as an example. Fish, a part of being a good source of digestible protein vitamins, minerals and polyunsaturated fatty acids (PUFAs), are also an important source of heavy metals. Some of the metals found in the fish might be essential as they play important role in biological system of the fish as well as in human being, some of them may also be toxic as might cause a serious damage in human health even in trace amount at a certain limit. A comprehensive study was conducted to fishes collected in Langkawi Island, a popular tourist destination in Malaysia and the overall findings revealed that from the human health point of view, the fin is a type offish found in the coastal areas of the island are safe for the consumption. The mineral and heavy metal contents are within the allowable limit of consumption.
    Matched MeSH terms: Malaysia
  7. Siti Radziah Shaik Alaudeen, Aszrin Abdullah, Azarisman Shah Mohd Shah, Norlelawati Abdul Talib
    MyJurnal
    Copy number variation (CNV) caused by changes in DNA sequences of 1000
    or more bases is implicated with susceptibility to common diseases. A study on CNV
    esv27061 among hypertensive Australian adults reported association with high blood
    pressure (BP). In Malaysia, no study on CNV among hypertensive young adults is
    available. Thus, this investigation aimed to assess the CNV esv27061 of young Malaysian
    adults with high blood pressure using optimized ddPCR. (Copied from article).
    Matched MeSH terms: Malaysia
  8. Kasvar, K.K., Nagapan, S., Abdullah, A.H., Ullah, K., Deraman, R., Yunus, R., et al.
    MyJurnal
    Concrete and masonry waste are the main types of waste typically generated at a construction project. There is a lack of studies in the country regarding the cost implication of managing these types of construction waste To address this need in Malaysia, the study is carried out to measure the disposal cost of concrete and masonry waste. The study was carried out by a site visit method using an indirect measurement approach to quantify the quantity of waste generated at the project. Based on the recorded number of trips for waste collection, the total expenditure to dispose the waste were derived in three construction stages. Data was collected four times a week for the period July 2014 to July 2015. The total waste generated at the study site was 762.51 m3 and the cost incurred for the 187 truck trips required to dispose the waste generated from the project site to the nearby landfill was RM22,440.00. The findings will be useful to both researchers and policy makers concerned with construction waste.
    Matched MeSH terms: Malaysia
  9. Kurubaran Ganasegeran, Sami Abdo Radman Al-Dubai, Surajudeen Abiola Abdulrahman, Sivashunmugam Sangaran, Hau, Wilson Wuei Yeow, Pukunan Renganathan
    ASEAN Journal of Psychiatry, 2017;18(2):226-235.
    MyJurnal
    Objectives: With the explosion in the use of WhatsApp Messenger globally, the revalence of late-night WhatsApping is poised to show a commensurate increase. This has sparked debates on a possible new wave of technological addiction that could cause serious psycho-behavioral repercussions. Acknowledging the ubiquity of WhatsApp, healthcare professionals have adopted it as a preferred communication tool in clinical practice. This preliminary cross-sectional study aimed to explore the prevalence of and psycho-behavioral factors associated with late-night WhatsApping.
    Methods: It was conducted on a universal sample of 307 healthcare professionals across medical and casualty departments in a Malaysian public hospital. The self-administered questionnaire consisted of items on socio-demographics, WhatsApp usage characteristics, and psycho-behavioral attributes.
    Results: Majority of respondents (72.9%) reported late-night WhatsApping habits. In multivariate analyses, late-night WhatsApping was significantly higher among those who used WhatsApp for more than 12 months (Adjusted odds ratio, AOR = 4.4, 95% Confidence interval, CI 2.2–8.8, p < 0.001), those who frequently kept
    mobile data on to avoid missing WhatsApp messages (AOR = 3.2, 95% CI 1.3–5.8, p = 0.006), those with frequent social connections (AOR = 3.0, 95% CI 1.4–6.4, p = 0.003), and those living alone (AOR = 2.3, 95% CI 1.1–5.2, p = 0.038).
    Conclusion: Late-night WhatsApping was significantly associated with usage characteristics and psycho-behavioral attributes.
    Matched MeSH terms: Malaysia
  10. Mohammad NB, Rahman NAA, Haque M
    J Pharm Bioallied Sci, 2018 4 17;10(1):7-14.
    PMID: 29657502 DOI: 10.4103/jpbs.JPBS_227_17
    Background: Cardiovascular disease (CVD) is a leading cause of death around the world including Malaysia. Ischemic heart disease (IHD) is the single largest cause of death in the developed countries and is one of the main contributors to the disease burden in developing countries.
    Materials and Methods: This was a cross-sectional study conducted to determine knowledge, attitude, and practice (KAP) regarding the risk of CVD in patients attending an outpatient clinic in Kuantan, Malaysia. A total of 100 patients comprising 52 male and 48 female subjects were selected through convenient sampling method.
    Results: Of the total subjects, 86% were Malays. The mean scores (standard deviation) for KAP were 60.75±4.823, 54.36±8.711, and 33.43±4.046, respectively, whereas the maximum scores obtained by the subjects for KAP were 71, 65, and 43, respectively. Regarding questions related to knowledge, 88% subjects knew irregular eating pattern can cause disease and the benefits of vegetable intake. Most subjects recognized that smoking and obesity were CVD risk factors. Regarding questions related to attitude, 96% agreed that exercise can prevent CVD. More than half of the subjects followed healthy lifestyle. There were statistically significant differences observed in knowledge level between sexes (P = 0.046) and races (P = 0.001). Nevertheless, there was no statistically significant difference observed in KAP across different education levels of the subjects regarding the risk of CVD (P-value = 0.332, 0.185, and 0.160, respectively).
    Conclusion: This study revealed that patients had good knowledge and attitude regarding CVD risk factors. Yet, the number of smokers is still quite high. Development of better public information system is essential for the well-being of the society.
    Matched MeSH terms: Malaysia
  11. Khoo SSK, Chu CM, Fung YK
    Case Rep Cardiol, 2018;2018:4827907.
    PMID: 29713551 DOI: 10.1155/2018/4827907
    Severe thyrotoxicosis can present with a myriad of cardiovascular complications. It may be mild features such as palpitations, tachycardia, and exertional dyspnea or may progress to life-threatening consequences such as atrial fibrillation, tachyarrhythmias, heart failure, myocardial infarction, and shock. In rare cases, they may present with myocardial ischemia secondary to coronary artery vasospasm. We report a case of a 59-year-old Malay gentleman who presented with fast atrial fibrillation and tachycardia-mediated heart failure that evolved to a silent myocardial infarction secondary to severe coronary artery vasospasm with undiagnosed severe thyrotoxicosis. He had complete resolution of heart failure and no further recurrence of coronary artery vasospasm once treatment for thyrotoxicosis was initiated and euthyroidism achieved. This life-threatening consequence has an excellent prognosis if recognised early and treated promptly.
    Matched MeSH terms: Malaysia
  12. Li, Sa Lau, Talwar, P.Y., Shahren Ahmad Zaidi Adruce, Yin, Bee Oon
    MyJurnal
    Perceived work environment could be described as the opinions and attitudes of workers towards their work condition. Elements of perceived work environment such as physical environment, supportive work environment, and perceived work tasks may possibly be important factors that influence the occurrence of accidents. The objective of this study is to examine the relationship between perceived work environment and the occurrence of accidents within an electronic manufacturing industry in Kuching, Sarawak. A cross-sectional survey utilizing a bilingual self-report questionnaire was conducted to garner data from 50 workers. Independent t-test and Pearson moment correlation were used to assess data. The results indicated that the occurrence of accidents was not affected by age group. Although physical environment and perceived work tasks did not demonstrate significant relationships with the occurrence of accidents, supportive work environment exhibited a significant inverse relationship, thereby indicating that accidents could be lowered in the presence of higher supportive work environment. Thus, support and help from co-workers are essential determinants of safety at the workplace.
    Matched MeSH terms: Malaysia
  13. Norain Abdul Rashid
    MyJurnal
    Traumatic brain injury (TBI) is a major medical and socioeconomic
    problem. Patients with severe TBI shows physical and functional improvement but
    remain with cognitive and psycho-social problem throughout recovery. Despite all the
    issues, the impact of TBI on long-term survivors in Malaysia is unknown. The aim of this
    study is to measure the functional level of ICU survivors with severe TBI within 6 months
    post injury. (Copied from article).
    Matched MeSH terms: Malaysia
  14. Jalalonmuhali M, Elagel SMA, Tan MP, Lim SK, Ng KP
    Int J Nephrol, 2018;2018:3081518.
    PMID: 29862077 DOI: 10.1155/2018/3081518
    Background: To assess the performance of different GFR estimating equations, test the diagnostic value of serum cystatin-C, and compare the applicability of cystatin-C based equation with serum creatinine based equation for estimating GFR (eGFR) in comparison with measured GFR in the elderly Malaysian patients.

    Methods: A cross-sectional study recruiting volunteered patients 65 years and older attending medical outpatient clinic. 51 chromium EDTA (51Cr-EDTA) was used as measured GFR. The predictive capabilities of Cockcroft-Gault equation corrected for body surface area (CGBSA), four-variable Modification of Diet in Renal Disease (4-MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations using serum creatinine (CKD-EPIcr) as well as serum cystatin-C (CKD-EPIcys) were calculated.

    Results: A total of 40 patients, 77.5% male, with mean measured GFR 41.2 ± 18.9 ml/min/1.73 m2 were enrolled. Mean bias was the smallest for 4-MDRD; meanwhile, CKD-EPIcr had the highest precision and accuracy with lower limit of agreement among other equations. CKD-EPIcys equation did not show any improvement in GFR estimation in comparison to CKD-EPIcr and MDRD.

    Conclusion: The CKD-EPIcr formula appears to be more accurate and correlates better with measured GFR in this cohort of elderly patients.

    Study site: medical outpatient clinic. University of Malaya Medical Centre (UMMC)
    Matched MeSH terms: Malaysia
  15. Sabarinah Sh Ahmad, Noraini Ahmad, Anuar Talib
    MyJurnal
    Safe level of daylighting for artefact conservation in historic buildings is a difficult task to achieve. Previous studies indicated that lighting problems in historic museum galleries were mainly due to unshaded walls that allowed direct sun penetration over the display areas. Ceiling geometry can also affect the daylighting performance significantly, particularly on the interior distribution of light. Malaysia, with hot and humid climate, and tropical sky conditions receives plenty of natural light all year around. The fluxes in natural lighting exposures confirm the need for strategic daylight control programme in the exhibition gallery. The study aims to assess the ceiling geometry contribution for four orientations; North, East, South and West through computer simulations. The research approach was based on comparisons between pitched and flat ceiling simulation output data. Further comparisons were performed with the recommended lighting limits for conservation of artefacts. The comparisons allowed better understanding of light damage issues and highlight the control of daylighting distributions through realistic predictive images and ceiling geometry designs. The results showed that the types of exhibits materials and its placement are affected by the ceiling geometry and constant changes in natural lighting exposure. The study confirms that ceiling geometry can act as a control mechanism with the environment physical features as part of preventive conservation criteria in the exhibition gallery. Thus, a systematic light-monitoring programme in the exhibition gallery is necessary to control illuminance level and cumulative exposure limits, for artefact preservation.
    Matched MeSH terms: Malaysia
  16. Tan BK, Tan SB, Chen LC, Chang KM, Chua SS, Balashanker S, et al.
    Patient Prefer Adherence, 2017;11:1027-1034.
    PMID: 28652712 DOI: 10.2147/PPA.S132894
    PURPOSE: Poor adherence to tyrosine kinase inhibitors (TKIs) could compromise the control of chronic myeloid leukemia (CML) and contributes to poorer survival. Little is known about how medication-related issues affect CML patients' adherence to TKI therapy in Malaysia. This qualitative study aimed to explore these issues.

    PATIENTS AND METHODS: Individual face-to-face, semistructured interviews were conducted at the hematology outpatient clinics of two medical centers in Malaysia from August 2015 to January 2016. CML patients aged ≥18 years who were prescribed a TKI were invited to participate in the study. Interviews were audio-recorded, transcribed verbatim, and thematically analyzed.

    RESULTS: Four themes were identified from 18 interviews: 1) concerns about adverse reactions to TKIs, 2) personal beliefs regarding the use of TKIs, 3) mismanagement of TKIs in daily lives, and 4) financial burden in accessing treatment. Participants skipped their TKIs due to ineffective emesis control measures and perceived wastage of medication from vomiting. Participants also modified their TKI therapy due to fear of potential harm from long-term use, and stopped taking their TKIs based on belief in curative claims of traditional medicines and misconception about therapeutic effects of TKIs. Difficulty in integrating the dosing requirements of TKIs into daily lives led to unintentional skipping of doses, as well as the risk of toxicities from inappropriate dosing intervals or food interactions. Furthermore, financial constraints also resulted in delayed initiation of TKIs, missed clinic appointments, and treatment interruptions.

    CONCLUSION: Malaysian CML patients encountered a range of medication-related issues leading to a complex pattern of nonadherence to TKI therapy. Further studies should investigate whether regular contact with patients to improve understanding of treatment rationale, to elicit and address patients' concerns about adverse reactions, and to empower patients with skills to self-manage their medications might promote better adherence to TKIs and improve CML patients' outcome.

    Study site: hematology outpatient clinics of Ampang Hospital (AH) and University Malaya Medical Centre (UMMC) in Malaysia
    Matched MeSH terms: Malaysia
  17. Ghani AAA, Shahudin MS, Zamri-Saad M, Zuki AB, Wahid H, Kasim A, et al.
    Vet World, 2017 Jun;10(6):630-635.
    PMID: 28717314 DOI: 10.14202/vetworld.2017.630-635
    AIM: The study was conducted at a smallholder goat farm located in Labu, Negeri Sembilan, Malaysia. The objective of this study was to evaluate the effect of proper feeding program on growth performances of replacement breeder goats.

    MATERIALS AND METHODS: A total of 30 healthy female boer cross goats at the age of 4 months old with average initial live body weight (BW) of 20.05±0.5 kg were used for on-farm feeding trial to evaluate the growth performance as preparation for breeding purposes. The experimental goats were divided into two groups of 15 animals each labeled as control and treatment groups, which were kept under intensive farming system. Goats in control group were fed with normal routine feeding protocol practiced by the farmer, while goats in the treatment group were fed with new feed formulation. Throughout the experimental period, on-farm monitoring and data collection were carried out. Initial BW and body condition score (BCS) were recorded before the start of the experiment while final BW and BCS were gained after 7 months of the experimental period. Average daily gain (ADG) was calculated after the experiment end. Data on BW, ADG, and BCS were recorded from both groups for every 2 weeks and reported monthly. The feed intake for the control group was 2.8 kg/animal/day which practiced by the farmer and 3.2 kg/animal/day as new feed formulation for the treatment group.

    RESULTS: After 7 months of the experimental period, final BW shows an improvement in treatment group (39.1±1.53 kg) compared with control group (32.3±1.23 kg). The ADG in treatment group also gives promising result when comparing with control group. Goats in treatment group significantly attained better ADG than control group which were 126.7 g/day and 83.3 g/day, respectively. For the BCS, goats in the treatment group had shown an improvement where 86.67% (13 out of 15) of the group had BCS ≥3 (1-5 scoring scale) and only 66.67% (10 out of 15) of the control group had BCS ≥3.

    CONCLUSION: Therefore, it was concluded that implementation of proper feeding program as shown in treatment group give promising result to improve the growth performance of replacement breeder goats which can be adopted by the farmers to improve farm productivity.

    Matched MeSH terms: Malaysia
  18. Maimunah Abdul Muna’aim, Yee, Tey Yin, Alya Az-Zahra Mohamad Zafarullah, Rafidah Md Saleh, Nazri Omar
    MyJurnal
    Introduction: Dry eye is a common but under-diagnosed problem in the general population. Lack of standardised diagnostic protocol causes prevalence of dry eye varied widely in different populations. Nevertheless, effective management rests largely on the accurate diagnosis and identification of the contributing risk factors.
    Methods: In a cross sectional study, socio-demographic, lifestyle and medical history data were collected from 157 respondents. A validated six-item questionnaire was used to determine the dry eye symptoms. Dry eye was determined by using Schirmer’s test. Fluorescein staining test and tear break up time (TBUT) test were performed to characterise the dry eye.
    Results: Using the Schirmer’s test, 33.8% of respondents had dry eyes. The likelihood of dry eye increased among Malay females in the seventh decade. The most frequently reported symptom was sensation of dryness of the eye. Although only 22.6% of dry eye cases were symptomatic, up to 47.2% of them may developed surface changes detectable by fluorescein dye test. Ethnicity (p=0.019) and diabetes mellitus (p=0.049) were significantly associated with dry eye.
    Conclusion: Dry eye could be subclinical but clinical tests in potential risk groups can lead to better detection of this condition and allow prescription of appropriate treatment for affected patients.
    Study site: Ophthalmology clinic, hospital, Malaysia
    Matched MeSH terms: Malaysia
  19. Lee JY, Wong CP, Tan CSS, Nasir NH, Lee SWH
    BMJ Open Diabetes Res Care, 2017;5(1):e000365.
    PMID: 28761651 DOI: 10.1136/bmjdrc-2016-000365
    OBJECTIVE: We evaluated the beliefs, experience and diabetes management strategies of type 2 diabetes mellitus (T2DM) Muslim patients that chose to fast during Ramadan.
    RESEARCH DESIGN AND METHODS: A semistructured focus group interview was conducted with 53 participants with T2DM. Participants were purposefully sampled and asked to share their perspective on Ramadan fasting. All interviews were audio recorded, transcribed verbatim and analyzed thematically.
    RESULTS: Participants reported optimism towards fasting during Ramadan, as they believed that fasting was beneficial to their overall well-being, and a time for family bonding. Most participants made limited attempts to discuss with their doctors on the decision to fast and self-adjusted their medication based on experience and symptoms during this period. They also reported difficulty in managing their diet, due to fear of hypoglycemia and the collective social aspect of fasting.
    CONCLUSION: Muslims are optimistic about their well-being when fasting during Ramadan. Many choose to fulfill their religious obligation despite being discouraged by their doctors. Collaboration with religious authorities should be explored to ensure patients receive adequate education before fasting during Ramadan.
    TRIAL REGISTRATION NUMBER: NCT02189135; Results.
    Matched MeSH terms: Malaysia
  20. Hafid HS, Nor 'Aini AR, Mokhtar MN, Talib AT, Baharuddin AS, Umi Kalsom MS
    Waste Manag, 2017 Sep;67:95-105.
    PMID: 28527863 DOI: 10.1016/j.wasman.2017.05.017
    In Malaysia, the amount of food waste produced is estimated at approximately 70% of total municipal solid waste generated and characterised by high amount of carbohydrate polymers such as starch, cellulose, and sugars. Considering the beneficial organic fraction contained, its utilization as an alternative substrate specifically for bioethanol production has receiving more attention. However, the sustainable production of bioethanol from food waste is linked to the efficient pretreatment needed for higher production of fermentable sugar prior to fermentation. In this work, a modified sequential acid-enzymatic hydrolysis process has been developed to produce high concentration of fermentable sugars; glucose, sucrose, fructose and maltose. The process started with hydrothermal and dilute acid pretreatment by hydrochloric acid (HCl) and sulphuric acid (H2SO4) which aim to degrade larger molecules of polysaccharide before accessible for further steps of enzymatic hydrolysis by glucoamylase. A kinetic model is proposed to perform an optimal hydrolysis for obtaining high fermentable sugars. The results suggested that a significant increase in fermentable sugar production (2.04-folds) with conversion efficiency of 86.8% was observed via sequential acid-enzymatic pretreatment as compared to dilute acid pretreatment (∼42.4% conversion efficiency). The bioethanol production by Saccharomyces cerevisiae utilizing fermentable sugar obtained shows ethanol yield of 0.42g/g with conversion efficiency of 85.38% based on the theoretical yield was achieved. The finding indicates that food waste can be considered as a promising substrate for bioethanol production.
    Matched MeSH terms: Malaysia
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