• 1 Penang Hospital, Pulau Pinang, Malaysia
  • 2 Punithavathi Narayanan, Research Physician, Hospital Pulau Pinang, Clinical Research Centre, Jalan residency, 10990 Penang, Malaysia Email:
  • 3 Penang, Hospital, Pulau Pinang, Malaysia
  • 4 Ranbaxy (Malaysia) Sdn. Bhd.
Med J Malaysia, 2011 Aug;66(3):214-9.
PMID: 22111443


A multicentre study was conducted to assess the long term efficacy and safety of a generic atorvastatin in the treatment of primary hypercholesterolaemia. Eighty five patients who received 10mg or 20 mg of atorvastatin for 8 weeks depending on target cholesterol goal were followed up by their own physicians and had final evaluation at 52 weeks. Reduction in mean low density Lipoprotein (LDL-C) was 36.5%, 37.9% and 32.2% at weeks 4, 8 and 52 respectively. LDL-C target was maintained in 81% and 69% of patients at week 8 and 52 respectively without drug related serious adverse events. Generic atorvastatin is safe and effective in usual clinical care setting.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.