Mycobacterial antibody levels and immune restoration disease in HIV patients treated in South East Asia

Sumatoh HR 1 , Oliver BG , Kumar M , Elliott JH , Vonthanak S , Vun MC Show all authors , Singh S , Agarwal U , Kumar A , Tan HY , Kamarulzaman A , Yunihastuti E , Saraswati H , Price P

Affiliations 

  • 1 School of Pathology & Laboratory Medicine, University of Western Australia, Perth, Australia
Biomark Med, 2011 Dec;5(6):847-53.
PMID: 22103621 DOI: 10.2217/bmm.11.79

Abstract

Immune restoration disease (IRD) associated with Mycobacterium tuberculosis parallels the reconstitution of a pathogen-specific Th1 response. However, it is not clear whether humoral responses to M. tuberculosis antigens also rise, or whether antibody levels predict IRD. Here, humoral immunity to M. tuberculosis antigens was investigated in four Asian cohorts.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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