• 1 Institute of Biological Science, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Primary Care Medicine, Faculty of Medicine, UiTM Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia
  • 4 School of Life Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
  • 5 Department of Infectious Disease Epidemiology and London Centre for Neglected Tropical Disease Research, School of Public Health, St Mary's Campus, Imperial College London, London, W2 1PG, UK
  • 6 Department of Pathobiology and Population Sciences and London Centre for Neglected Tropical Disease Research, Royal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire, AL97TA, UK
  • 7 School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK
  • 8 Institute for Research Molecular Medicine, University of Science Malaysia, Gelugor, Penang, Malaysia
  • 9 MAHSA University, Jalan Elmu off Jalan University, Kuala Lumpur, Malaysia
  • 10 Institute of Biological Science, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
Parasit Vectors, 2017 May 15;10(1):238.
PMID: 28506241 DOI: 10.1186/s13071-017-2167-8


BACKGROUND: The number of migrants working in Malaysia has increased sharply since the 1970's and there is concern that infectious diseases endemic in other (e.g. neighbouring) countries may be inadvertently imported. Compulsory medical screening prior to entering the workforce does not include parasitic infections such as toxoplasmosis. Therefore, this study aimed to evaluate the seroprevalence of T. gondii infection among migrant workers in Peninsular Malaysia by means of serosurveys conducted on a voluntary basis among low-skilled and semi-skilled workers from five working sectors, namely, manufacturing, food service, agriculture and plantation, construction and domestic work.

METHODS: A total of 484 migrant workers originating from rural locations in neighbouring countries, namely, Indonesia (n = 247, 51.0%), Nepal (n = 99, 20.5%), Bangladesh (n = 72, 14.9%), India (n = 52, 10.7%) and Myanmar (n = 14, 2.9%) were included in this study.

RESULTS: The overall seroprevalence of T. gondii was 57.4% (n = 278; 95% CI: 52.7-61.8%) with 52.9% (n = 256; 95% CI: 48.4-57.2%) seropositive for anti-Toxoplasma IgG only, 0.8% (n = 4; 95% CI: 0.2-1.7%) seropositive for anti-Toxoplasma IgM only and 3.7% (n = 18; 95% CI: 2.1-5.4%) seropositive with both IgG and IgM antibodies. All positive samples with both IgG and IgM antibodies showed high avidity (> 40%), suggesting latent infection. Age (being older than 45 years), Nepalese nationality, manufacturing occupation, and being a newcomer in Malaysia (excepting domestic work) were positively and statistically significantly associated with seroprevalence (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.