Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study

Leong DP 1 , Teo KK 2 , Rangarajan S 3 , Lopez-Jaramillo P 4 , Avezum A 5 , Orlandini A 6 Show all authors , Seron P 7 , Ahmed SH 8 , Rosengren A 9 , Kelishadi R 10 , Rahman O 11 , Swaminathan S 12 , Iqbal R 13 , Gupta R 14 , Lear SA 15 , Oguz A 16 , Yusoff K 17 , Zatonska K 18 , Chifamba J 19 , Igumbor E 20 , Mohan V 21 , Anjana RM 21 , Gu H 22 , Li W 22 , Yusuf S 2 , Prospective Urban Rural Epidemiology (PURE) Study investigators

Affiliations 

  • 1 Population Health Research Institute, McMaster University, Hamilton, ON, Canada; Hamilton Health Sciences, Hamilton, ON, Canada. Electronic address: leongd@phri.ca
  • 2 Population Health Research Institute, McMaster University, Hamilton, ON, Canada; Hamilton Health Sciences, Hamilton, ON, Canada
  • 3 Population Health Research Institute, McMaster University, Hamilton, ON, Canada
  • 4 Fundacion Oftalmologica de Santander and Medical School, Universidad de Santander, Colombia
  • 5 Dante Pazzanese Institute of Cardiology, São Paulo University, Brazil
  • 6 ECLA Foundation, Instituto Cardiovascular de Rosario, Rosario, Argentina
  • 7 Universidad de La Frontera, Temuco, Chile
  • 8 Dubai Health Authority, Dubai, United Arab Emirates
  • 9 Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • 10 Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  • 11 Independent University, Dhaka, Bangladesh
  • 12 St. John's Medical College, St. John's Research Institute, Bangalore, India
  • 13 Department of Community Health Sciences and Medicine, Aga Khan University, Karachi, Pakistan
  • 14 Fortis Escorts Hospital, Jaipur, India
  • 15 Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada
  • 16 Department of Internal Medicine, Istanbul Medeniyet University, Istanbul, Turkey
  • 17 Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia; UCSI University, Cheras, Kuala Kumpur, Malaysia
  • 18 Department of Social Medicine, Medical University of Wrocław, Wrocław, Poland
  • 19 University of Zimbabwe, Harare, Zimbabwe
  • 20 School of Public Health, University of the Western Cape, Cape Town, South Africa
  • 21 Madras Diabetes Research Foundation, Chennai, India
  • 22 State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
Lancet, 2015 Jul 18;386(9990):266-73.
PMID: 25982160 DOI: 10.1016/S0140-6736(14)62000-6

Abstract

Reduced muscular strength, as measured by grip strength, has been associated with an increased risk of all-cause and cardiovascular mortality. Grip strength is appealing as a simple, quick, and inexpensive means of stratifying an individual's risk of cardiovascular death. However, the prognostic value of grip strength with respect to the number and range of populations and confounders is unknown. The aim of this study was to assess the independent prognostic importance of grip strength measurement in socioculturally and economically diverse countries.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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