Six-year study on peripheral venous catheter-associated BSI rates in 262 ICUs in eight countries of South-East Asia: International Nosocomial Infection Control Consortium findings

Rosenthal VD 1 , Bat-Erdene I 2 , Gupta D 3 , Rajhans P 4 , Myatra SN 5 , Muralidharan S 6 Show all authors , Mehta Y 7 , Rai V 8 , Hung NV 9 , Luxsuwong M 10 , Tapang ARD 11 , Guo X 12 , Trotter A 13 , Kharbanda M 14 , Rodrigues C 15 , Dwivedy A 16 , Shah S 17 , Poojary A 18 , Todi SK 19 , Chabukswar S 20 , Bhattacharyya M 21 , Ramachandran B 22 , Ramakrishnan N 23 , Purkayasta SK 24 , Sakle AS 25 , Kumar S 26 , Warrier AR 27 , Kavathekar MS 28 , Sahu S 29 , Mubarak A 30 , Modi N 31 , Jaggi N 32 , Gita N 33 , Mishra SB 34 , Sahu S 35 , Jawadwala B 36 , Zala D 37 , Zompa T 38 , Mathur P 39 , Nirkhiwale S 40 , Vadi S 41 , Singh S 42 , Agarwal M 43 , Sen N 44 , Karlekar A 45 , Punia DP 46 , Kumar S 47 , Gopinath R 48 , Nair PK 49 , Gan CS 50 , Chakravarthy M 51 , Sandhu K 52 , Kambam C 53 , Mohanty SK 54 , Varaiya A 55 , Pandya N 56 , Subhedar VR 57 , Vanajakshi MR 58 , Singla D 59 , Tuvshinbayar M 60 , Patel M 61 , Ye G 62 , Lum LCS 63 , Zaini RHM 64 , Batkhuu B 65 , Dayapera KM 66 , Nguyet LT 67 , Berba R 68 , Buenaflor MCS 69 , Ng JA 70 , Siriyakorn N 71 , Thu LTA 72

Affiliations 

  • 1 International Nosocomial Infection Control Consortium (INICC), Buenos Aires, Argentina
  • 2 Infection Control Professionals of Mongolia, and Intermed Hospital, Ulaanbaatar, Mongolia
  • 3 BM Birla Heart Research Centre, Kolkata, India
  • 4 Deenanath Mangeshkar Hospital, Pune, India
  • 5 Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India
  • 6 G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India
  • 7 Medanta The Medicity, New Delhi, India
  • 8 Adult Intensive Care Unit, University Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 9 Bach Mai Hospital, Hanoi, Vietnam
  • 10 Phyathai 1 Hospital, Pratumthani, Thailand
  • 11 Cardinal Santos Medical Center, San Juan, Philippines
  • 12 Dong E Peoples Hospital, Shandong, P.R. China
  • 13 Grande International Hospital, Kathmandu, Nepal
  • 14 Desun Hospital, Kolkata, India
  • 15 P. D. Hinduja National Hospital and Medical Research Centre, Mumbai, India
  • 16 Dr L H Hiranandani Hospital, Mumbai, India
  • 17 Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India
  • 18 Breach Candy Hospital Trust, Mumbai, India
  • 19 Advanced Medicare Research Institute Dhakuria Unit, Kolkata, India
  • 20 Noble Hospital, Pune, India
  • 21 Advanced Medicare Research Institute Mukundapur Unit, Kolkata, India
  • 22 Kanchi Kamakoti Childs Trust Hospital, Chennai, India
  • 23 Apollo Main Hospital, Chennai, India
  • 24 Peerless Hospital Research Center Ltd., Kolkata, India
  • 25 Bombay Hospital & Medical Research Centre, Mumbai, India
  • 26 Kovai Medical Center and Hospital, Coimbatore, India
  • 27 Aster Medcity, Kochi, India
  • 28 Sahyadri Speciality Hospital, Pune, India
  • 29 Kalinga Hospital, Bhubaneswar, India
  • 30 Kerala Institute of Medical Sciences, Thiruvananthapuram, India
  • 31 Indraprastha Apollo Hospital, New Delhi, India
  • 32 Artemis Health Institute, New Delhi, India
  • 33 Rao Nursing Home, Pune, India
  • 34 IMS and SUM Hospital, Bhubaneswar, India
  • 35 Apollo Hospital, Bhubaneswar, India
  • 36 Saifee Hospital, Mumbai, India
  • 37 Shri Vinoba Bhave Civil Hospital, Silvassa, India
  • 38 Max Super Speciality Hospital, Dehradun, Dehradun, India
  • 39 JPNA Trauma Center, AIIMS, New Delhi, India
  • 40 Greater Kailash Hospital, Indore, India
  • 41 Global Hospital, Mumbai, India
  • 42 Amrita Institute of Medical Sciences and Research Center, Kochi, India
  • 43 Belle Vue Clinic, Kolkata, India
  • 44 Christian Medical College, Vellore, India
  • 45 Escorts Heart Institute & Research Centre, New Delhi, India
  • 46 Mahatma Gandhi Hospital, Jaipur, India
  • 47 Apollo Children's Hospital, Chennai, India
  • 48 Nizam's Institute of Medical Sciences, Hyderabad, India
  • 49 Holy Spirit Hospital, Mumbai, India
  • 50 Pusat Perubatan Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 51 Fortis Hospitals, Bangalore, India
  • 52 Max Super Speciality Hospital, Saket, New Delhi, India
  • 53 Columbia Asia Hospital-Patiala, Patiala, India
  • 54 AMRI Hospitals, Bhubaneswar, India
  • 55 Dr. Balabhai Nanavati Super Speciality Hospital, Mumbai, India
  • 56 Bhailal Amin General Hospital, Vadodara, India
  • 57 Bombay Hospital Indore, Mumbai, India
  • 58 Columbia Asia Referral Hospital-Yeshwanthpur, Bangalore, India
  • 59 Maharaja Agrasen Hospital, New Delhi, India
  • 60 Second General Hospital, Ulaanbaatar, Mongolia
  • 61 Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, India
  • 62 Yangpu Hospital, Shanghai, P.R. China
  • 63 Pediatric Intensive Care, University Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 64 Intensive Care Unit, Hospital Universiti Sains Malaysia, Kubang Kerian, Malaysia
  • 65 Central State Hospital 1, Ulaanbaatar, Mongolia
  • 66 Healthserv Los Banos Medical Center, Los Baños, Philippines
  • 67 Thanh Nhan Hospital, Hanoi, Vietnam
  • 68 Philippine General Hospital, Manila, Philippines
  • 69 Philippine Heart Center, Manila, Philippines
  • 70 St. Luke's Medical Center-Quezon City, Manila, Philippines
  • 71 Phyathai 1 Hospital, Bangkok, Thailand
  • 72 Cho Ray Hospital, Ho Chi Minh City, Vietnam
J Vasc Access, 2021 Jan;22(1):34-41.
PMID: 32406328 DOI: 10.1177/1129729820917259

Abstract

BACKGROUND: Short-term peripheral venous catheter-associated bloodstream infection rates have not been systematically studied in Asian countries, and data on peripheral venous catheter-associated bloodstream infections incidence by number of short-term peripheral venous catheter days are not available.

METHODS: Prospective, surveillance study on peripheral venous catheter-associated bloodstream infections conducted from 1 September 2013 to 31 May 2019 in 262 intensive care units, members of the International Nosocomial Infection Control Consortium, from 78 hospitals in 32 cities of 8 countries in the South-East Asia Region: China, India, Malaysia, Mongolia, Nepal, Philippines, Thailand, and Vietnam. For this research, we applied definition and criteria of the CDC NHSN, methodology of the INICC, and software named INICC Surveillance Online System.

RESULTS: We followed 83,295 intensive care unit patients for 369,371 bed-days and 376,492 peripheral venous catheter-days. We identified 999 peripheral venous catheter-associated bloodstream infections, amounting to a rate of 2.65/1000 peripheral venous catheter-days. Mortality in patients with peripheral venous catheter but without peripheral venous catheter-associated bloodstream infections was 4.53% and 12.21% in patients with peripheral venous catheter-associated bloodstream infections. The mean length of stay in patients with peripheral venous catheter but without peripheral venous catheter-associated bloodstream infections was 4.40 days and 7.11 days in patients with peripheral venous catheter and peripheral venous catheter-associated bloodstream infections. The microorganism profile showed 67.1% were Gram-negative bacteria: Escherichia coli (22.9%), Klebsiella spp (10.7%), Pseudomonas aeruginosa (5.3%), Enterobacter spp. (4.5%), and others (23.7%). The predominant Gram-positive bacteria were Staphylococcus aureus (11.4%).

CONCLUSIONS: Infection prevention programs must be implemented to reduce the incidence of peripheral venous catheter-associated bloodstream infections.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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