AIM: This study aimed to determine the level of technostress associated with burnout and fatigue among healthcare workers (HCWs) in the state hospitals of Malaysia.
METHODS: A cross-sectional study was conducted from September 2022 to November 2023 among HCWs working in the 15-state hospitals in Malaysia. A standardized questionnaire was distributed among the HCWs in the state hospitals in Malaysia. The questionnaire contains information on socio-demography and topic-specific scales on technostress, burnout and fatigue.
RESULTS: A total of 1620 HCWs were included in the analysis, of which 244 (15%) have high level of technostress, 1089 (67%) have moderate technostress, and 287 (18%) have low technostress. Burnout, and fatigue were significantly associated with technostress. HCWs with moderate burnout were less likely to have high technostress compared to those with high burnout (B = -0.993, 95% CI; 0.231 - 0.594; p
METHODS: This study comprised a retrospective review of patients diagnosed with JRP at a tertiary care institute between January 2013 and January 2023. The inclusion criteria were a diagnosis of JRP, and treatment with at least one surgical intervention. Demographic, clinical, and treatment data were analysed, and statistical correlations were evaluated to identify indicators of disease severity and assess the likelihood of re-intervention.
RESULTS: This study enrolled 31 patients with a median age at symptom onset of 3.5 years. Māori children comprised 29 % of the cohort. Bilateral parotid gland involvement was observed in 74 % of cases, and patients experienced a median of six episodes annually. Lipiodol sialography was the most common initial intervention (61 %), associated with a 21 % re-intervention rate within one year. Sialendoscopy, an alternate treatment, required no re-interventions within the first year, but accounted for a smaller proportion of initial treatments due to limited expertise in the earlier years. Two patients (6 %) experienced major complications following lipiodol sialography.
CONCLUSION: Minimally invasive techniques, particularly sialendoscopy, demonstrated promising outcomes in managing JRP. However, treatment approaches may vary based on expertise and equipment availability. Larger randomised studies are required to establish optimal management strategies and understand the natural history of JRP.
RESULT: Increasing concentrations of experimental solution exposure significantly affect mean diameter of HAp. The increasing FTIR intensity, were displayed; 0.2% TCPCa3(PO4)2 Str/FL > 0.1% TCPCa3(PO4)2 Str/FL> control. 0.2% TCPCa3(PO4)2 Str/FL revealed existence of distinct crystals, with planes orientated perpendicular to longer axis of tooth. XRD pattern indicated crystal growth with a rise in peak intensities in 0.2% TCPCa3(PO4)2 Str/FL group. The NMR spectra for Glu and Ser-OPO3 elucidated interactions between carbon atoms in amino acid and hydrogen atoms on HAp surfaces. Surface microhardness of 0.2% TCPCa3(PO4)2 Str/FL specimens showed significantly higher values on day 28 (p< 0.05). ALP density value of cells was significantly higher for 0.2% TCPCa3(PO4)2 Str/FL group on day 7 and 14. 0.1% TCPCa3(PO4)2 Str/FL and 0.2% TCPCa3(PO4)2 Str/FL enhanced migration of PGF cells in comparison to the control group (p<0.05). 0.1% TCPCa3(PO4)2 Str/FL and 0.2% TCPCa3(PO4)2 Str/FL groups showed significant differences in bond strength at different time points CONCLUSION: 0.1% TCPCa3(PO4)2 Str/FL and 0.2% TCPCa3(PO4)2 Str/FL were structurally integrated into the lattice demonstrating changes within the crystallite size and became conducive for adhesive bonding.
CLINICAL SIGNIFICANCE: The new amino acid-based hydroxyapatite formulation is chemically stable due to the substitution of OH- with F- and is crucial in the rehardening of caries and adhesive bonding.
METHODS: This study employed a cross-sectional design involving Form 4 secondary school students from Terengganu. Hemoglobin variants were analyzed using CE (CAPILLARYS2 Flex-Piercing System) and HPLC (VARIANT II). Molecular testing, including multiplex polymerase chain reaction (PCR) and amplification refractory mutation system-PCR techniques, was carried out to detect alpha thalassemia mutations.
RESULTS: The prevalence of Hb CS revealed 92.2% heterozygous (mean zone 2 CE peak value of 0.7%), 7.2% compound heterozygous (mean zone 2 CE peak value of 1.2%), and 0.5% homozygous cases (mean zone 2 CE peak value of 4.5%).
CONCLUSION: The study highlights a significant prevalence of Hb CS among the Terengganu population, with heterozygous cases being the most common. The peak values in zone 2 CE varied significantly among the heterozygous, compound heterozygous, and homozygous HbCS cases, indicating the potential utility of these measurements in distinguishing between different clinical phenotypes.
MATERIALS AND METHODS: A web-based survey with 32 questions was developed in collaboration with the EAU Young Academic Urologists Urothelial Cancer Working Party. It was sent to urologists with more than five years of experience across different institutions globally. Descriptive statistics were used to evaluate the responses.
RESULTS: A total of 157 responses were received from urologists, representing a response rate of 65%. Most respondents (64.3%) found pathological reports comprehensive, although 36% reported unclear reports in some cases. Pathologists were contacted for clarification in less than 20% of cases. Notably, the reporting of pathological subtypes and depth of invasion was inconsistent among institutions.
CONCLUSION: The survey highlights variability in pathology report quality across centers. Standardized reporting, increased pathologist involvement in multidisciplinary teams, and adherence to international guidelines are necessary to improve the accuracy and clarity of pathology reports in urology.
MATERIALS AND METHODS: A systematic search was conducted in PubMed, Scopus, and the Cochrane Central Register of Controlled Studies for in-vitro studies from inception until December 2023 (PROSPERO: CRD42024501614). Network meta-analysis and pairwise meta-analysis were performed. The ranking was performed using the surface area under the cumulative ranking (SUCRA) guidelines.
RESULTS: Seven hundred forty-one articles were identified, of which 80 duplicates were removed, and 585 were excluded by screening the titles and abstracts. A total of 76 articles were assessed by full-text reading, and 16 were included in the quantitative synthesis. CAD-CAM fibre posts (SMD = 1.09 [95% CI: 0.01, 2.17]) P = 0.04 demonstrated higher bond strength when compared to pre-fabricated posts. CAD-CAM fibre posts (RR = 0.39 [95% CI: 0.23, 0.69]) P
METHOD: This retrospective study was conducted on patients hospitalized in a medical intensive care unit of a referral tertiary care center and subjected to antibiotics de-escalation over five years. Independent factors associated with mortality post antibiotics de-escalation were assessed. Various data were collected, including patient demographics, admission and discharge dates, a primary source of infection and free of infection status, choices of antibiotic used and de-escalation history, vital signs, data on X-ray changes, relevant laboratory investigations, microbiological culture history, mortality status, history of COVID-19 infection, presence of central line, number of vasopressors used, ventilator settings and respective SOFA scores.
RESULTS: Prevalence of mortality among patients continued on broad-spectrum antibiotics empirically is remarkable. Through this study, it was found that the significant factors associated with mortality post antibiotic de-escalation were hospital-acquired infection (HAI) (Adjusted OR: 12.56; 95% CI: 2.88,54.98; p