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Impact of six rounds of mass drug administration on Brugian filariasis and soil-transmitted helminth infections in eastern Indonesia

Supali T 1 , Djuardi Y 1 , Bradley M 2 , Noordin R 3 , Rückert P 4 , Fischer PU 5

Affiliations 

  • 1 Department of Parasitology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
  • 2 Global Health Programs, GlaxoSmithKline, Brentford, Middlesex, United Kingdom
  • 3 Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia
  • 4 German International Co-operation (GIZ), Kupang, Indonesia
  • 5 Department of Internal Medicine, Infectious Diseases Division, Washington University School of Medicine, St. Louis, Missouri, United States of America
PLoS Negl Trop Dis, 2013;7(12):e2586.
PMID: 24349595 DOI: 10.1371/journal.pntd.0002586

Abstract

The lymphatic filarial parasite Brugia timori occurs only in eastern Indonesia where it causes high morbidity. The absence of an animal reservoir, the inefficient transmission by Anopheles mosquitoes and the high sensitivity to DEC/albendazole treatment make this species a prime candidate for elimination by mass drug administration (MDA).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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