Displaying publications 41 - 60 of 346 in total

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  1. Mohammed A. Jasim, Mohd Sofian-azirun, Yusoff, Motior Rahman M
    Sains Malaysiana, 2016;45:119-127.
    In this paper we have studied the acute toxicity effect of Hg on hybrid tilapia (Oreochromis niloticus). For this, the tissues of tilapia have been digested by means of acids in microwave oven and was analyzed by flameless atomic absorption spectrophotometer (FAAS). We have identified that the levels of Hg varied significantly in different tissues and the metal concentration was in the following order: liver > gills > muscles; of which the maximum level recorded for Hg was 0.799 mg/kg. We have also observed the alterations towards histopathological aspects in the gills and liver of treated fishes were studied using light and electron microscopy, subjected to the exposure of Hg for 24 h and furthermore we have also noticed the extent of the increased alterations during the 96 h of exposure to median lethal concentration LC50 (0.3 mg/L) a severe disorganization of epithelial cells and modifications of the structure of the secondary lamellae. Moreover the severity has also found to increase to sub-lethal concentration (0.03 mgHg/L) in 21 days of exposure; Liver was slightly affected by the contamination of Hg. Ultimately, histopathology is considered as a sensitive technique of bioaccumulation and for the observing the potential damage from Hg exposure.
    Matched MeSH terms: Spectrophotometry, Atomic
  2. Palihakkara CR, Dassanayake S, Jayawardena C, Senanayake IP
    J Health Pollut, 2018 Mar;8(17):14-19.
    PMID: 30524845 DOI: 10.5696/2156-9614-8.17.14
    Background: Acid mine drainage (AMD) is a major environmental impact associated with the mining industry. Elevated acidic conditions resulting from the discharge of AMD into the surrounding environment can cause heavy metals to dissolve and transport through water streams and accumulate in the aquatic environment, posing a risk to the health of living organisms. There have been several novel approaches in the remediation of AMD involving passive treatment techniques. The constructed treatment wetland approach is a passive remediation option that has proven to be a cost effective and long-lasting solution in abating toxic pollutant concentrations.

    Objectives: The present study investigates the applicability of water hyacinth (Eichhornia crassipes), a tropical aquatic plant with reported heavy metal hyper-accumulation in microcosm floating wetland treatment systems designed to remediate AMD with copper (Cu) and cadmium (Cd) concentrations exceeding threshold limits.

    Methods: Twelve water hyacinth samples were prepared with varying concentrations of Cu (1 mg/L, 2 mg/L, 4 mg/L) and Cd (0.005 mg/L, 0.01 mg/L, 0.02 mg/L). Water samples of 5 ml each were collected from each sample at 24-hour intervals for analysis with an atomic absorption spectrometer.

    Results: Plant growth varied according to Cu and Cd concentrations and no plants survived for more than 14 days. There was a significant discrepancy in the rate at which the Cd concentrations abated. The rate of reduction was rapid for higher concentrations and after 24 hours a substantial reduction was achieved. There was a reduction in Cu concentration after the first 24-hour period, and after the next 24-hour period the concentrations were again elevated in the samples at initial concentrations of 2 mg/L and A4 mg/L. 4 mg/L Cu concentration was shown to be toxic to the plants, as they had low accumulations and rapid dying was evident.

    Conclusions: Water hyacinth has the capability to reduce both Cu and Cd concentrations, except at an initial concentration of 4 mg/L of Cu, which was toxic to the plants.

    Competing Interests: The authors declare no competing financial interests.

    Matched MeSH terms: Spectrophotometry, Atomic
  3. Rohman A, Che Man YB
    Food Chem, 2011 Nov 15;129(2):583-588.
    PMID: 30634271 DOI: 10.1016/j.foodchem.2011.04.070
    Currently, the authentication of virgin coconut oil (VCO) has become very important due to the possible adulteration of VCO with cheaper plant oils such as corn (CO) and sunflower (SFO) oils. Methods involving Fourier transform mid infrared (FT-MIR) spectroscopy combined with chemometrics techniques (partial least square (PLS) and discriminant analysis (DA)) were developed for quantification and classification of CO and SFO in VCO. MIR spectra of oil samples were recorded at frequency regions of 4000-650cm-1 on horizontal attenuated total reflectance (HATR) attachment of FTIR. DA can successfully classify VCO and that adulterated with CO and SFO using 10 principal components. Furthermore, PLS model correlates the actual and FTIR estimated values of oil adulterants (CO and SFO) with coefficient of determination (R2) of 0.999.
    Matched MeSH terms: Spectrophotometry, Infrared
  4. Ang HH, Lee KL
    Food Chem Toxicol, 2006 Aug;44(8):1245-50.
    PMID: 16567029 DOI: 10.1016/j.fct.2006.01.014
    The DCA (Drug Control Authority), Malaysia has implemented the phase three registration of traditional medicines on 1 January 1992. As such, a total of 100 products in various pharmaceutical dosage forms of a herbal preparation found in Malaysia, containing tongkat Ali hitam, either single or combined preparations, were analyzed for the presence of a heavy toxic metal, mercury, using atomic absorption spectrophotometer, after performing a simple random sampling to enable each sample an equal chance of being selected in an unbiased manner. Results showed that 26% of these products possessed 0.53-2.35 ppm of mercury, and therefore, do not comply with the quality requirement for traditional medicines in Malaysia. The quality requirement for traditional medicines in Malaysia is not exceeding 0.5 ppm for mercury. Out of these 26 products, four products have already registered with the DCA, Malaysia whilst the rest, however, have not registered with the DCA, Malaysia.
    Matched MeSH terms: Spectrophotometry, Atomic
  5. Lim SW, Loh HS, Ting KN, Bradshaw TD, Allaudin ZN
    Trop Life Sci Res, 2015 Apr;26(1):111-20.
    PMID: 26868595 MyJurnal
    The yellow tetrazolium salt 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) is widely used to determine cell viability in cell proliferation and cytotoxic assays. MTT is reduced by metabolically active cells to form an insoluble purple formazan product that is quantifiable by spectrophotometry. It is the most common and direct assay for cell viability. However, in this present study, we demonstrated that the vitamin E isomers α-β-γ-δ-tocotrienols and α-tocopherol were able to reduce MTT into a formazan product, despite the absence of living cells. For comparison, a second method for determining cell viability, which is the neutral red uptake assay, was used in parallel with the MTT assay. The results showed that neutral red did not interact with the vitamin E isomers. Our findings suggest that the MTT assay is not suitable for studying the proliferative effects of vitamin E isomers on cell growth.
    Matched MeSH terms: Spectrophotometry
  6. Lui JL, Tong SL, Teh SK
    Ann Dent, 1994;1(1):1-4.
    MyJurnal
    The mercury controversy related to dental amalgam is still continuing. In Malaysia, part of, this controversy has been attributed to a recently - introduced dental amalgam claimed to be non-mercury releasing and causing no mercury toxicity. The purpose of this study was to investigate whether this amalgam, Composil, was indeed non-mercury releasing. Six specimens each of Composil and a control (GS-80) were incubated at 3TC in deionised-distilled water. The daily mercury release was determined over a four-week study period using the stationary cold-vapour atomic absorption spectrometric method. The mean mercury release of Composil was 30.9 Ilg/cm2/ 24hr whilst that of GS-80 was 0.9 Ilg/cm2124hr and the difference was found to be highly significant (P < 0.00l). Results of this study therefore did not substantiate the manufacturer's claim. The release of mercury from amalgam restorations and their implications in clinical practice were also discussed.
    Matched MeSH terms: Spectrophotometry, Atomic
  7. Shamsul, B.S., Zakirah, M.
    MyJurnal
    The main objective of this study is to determine the association between respirable hexavalent chromium compounds with urinary β2-microglobulin levels among welders in an automotive components manufacturing plant. 49 welders and 39 workers involved in stamping process were selected as the exposed and the comparative group. β2-microglobulin is a protein renal tubular dysfunction marker that can indicate renal dysfunction caused by heavy metal. Air samples of worker’s breathing zone were collected using personal air sampling pump and filter papers. Filter papers were then diluted and analysed with Atomic Absorption Spectrophotometry (AAS). Workers’ urine samples were collected at the end of 8-hour work shift and analysed with β2-microglobulin ELISA Kit (IBL-Hamburg) and a microtiter reader. Meanwhile, creatinine levels were analysed with creatinine test strips and Reflotron®. A mean concentration of respirable hexavalent chromium compounds in air for the exposed group was 0.135 ± 0.043μg/m3 while for the non-exposed group was 0.124 ± 0.029μg/m3. The mean level of urinary β2-microglobulin per creatinine for the exposed group was 84.996 ± 39.246μg/g while that of the comparative group was 61.365 ± 21.609μg/g. The concentrations of respirable hexavalent chromium compounds were higher in the exposed group compared to the comparative group (Z=-2.444, p=0.015). β2-microglobulin level was also higher in the exposed group compared to the non-exposed group (t=3.821, p=
    Matched MeSH terms: Spectrophotometry, Atomic
  8. Shamsul, B.S., How Pai, S.
    MyJurnal
    Homocysteine could be a mechanism that underlies the effects of lead on cardiovascular system. This study aims to identify the relationship between lead exposure and homocysteine levels among workers. A comparative cross-sectional study was carried out on 80 workers of an automotive components manufacturing factory; that comprised of 40 exposed workers and 40 non-exposed workers. Blood samples of respondents were taken by fingerprick. The blood samples were analyzed for blood lead concentration by using Atomic Absorption Spectrometry Graphite Furnace Model GBC 908AA. Besides that, ELISA Kit was used to show the homocysteine level among the respondents. Questionnaires were used to obtain demography information of respondents. Results from the statistical analysis showed that the mean blood lead concentration for exposed respondents was 5.53±4.74 μg/dL and 3.53±2.81 μg/dL for the comparative respondents. Mann-Whitney U test showed that there was no significance difference between the mean blood lead concentration of the exposed and comparative group (z=-1.178; p=0.075). The blood lead concentration ranged 0.68-17.95 among the exposed group and with a range of 0.084-11.96 for the comparative group. The mean homocysteine level (μmol/L) was 32.48±2.481μmol/L for the exposed group and 16.50±4.0960 μmol/L for the comparative group. There was a significant difference in homocysteine level (μmol/L) between the exposed (32.48±2.481) and comparative (16.50±4.0959) groups (z = -7.699, p
    Matched MeSH terms: Spectrophotometry, Atomic
  9. Abbas F.M.A., Saifullah, R., Azhar, M.E.
    MyJurnal
    Cavendish (Musa paradisiaca L, cv cavendshii) and Dream (Musa acuminata colla. AAA, cv ‘Berangan’) banana flours were prepared from ripe fruits collected from eleven markets located in Penang, Malaysia. The mineral composition (Na, K, Ca, Mg, Cu, Fe, Mn, Zn) of the flour were analyzed by atomic absorption spectrophotometer and the data obtained were analyzed using logistic regression model. Ripe banana flours were rich source of K and a fair source of other minerals, however logistic regression model identified Mg as an indicator to discriminate between the two types of banana flour affording 100 % correct assignation. Based on this result, mineral analysis may be suggested as a method to authenticate ripe banana flour. This study also presents the usefulness of logistic regression technique for analysis and interpretation of complex data.
    Matched MeSH terms: Spectrophotometry, Atomic
  10. Tan, Y.P., Wong, Y.C.
    MyJurnal
    Bismuth chromium solid solutions, with a general formula Bi6-xCr2Oδ, where -1 ≤ x ≤ 2, were successfully synthesized via the conventional solid state method. The phases of the synthesized samples were determined by X-ray diffraction (XRD) analysis. The properties of single-phase compounds were characterized by using differential thermal analysis (DTA), thermal gravimetric analysis (TGA), AC impedance spectroscopy, and inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The occurrence of phase transitions was confirmed by DTA and TGA, where a thermal event was observed by DTA at around 800oC. In addition, TGA studies also showed that there was a weight loss at around 800oC. Elemental analysis of Bi6Cr2O15 and its solid solutions by ICP-AES showed a good agreement between the expected value and the experimental value on the compositions, with no evidence of any systematic deviation from stoichiometric. Electrical properties of Bi6Cr2O15 and its solid solutions were investigated by using AC impedance spectroscopy from 300oC to 650oC. Ionic conductivity increased with the increasing temperature and bismuth content, and the best ionic conductivity was observed for Bi7Cr2O16.5. The activation energy (Ea) of Bi6Cr2O15 and its solid solutions were in the range of 1.22-1.32 eV.
    Matched MeSH terms: Spectrophotometry, Atomic
  11. Mas Ezatul Nadia Mohd Ruah, Nor Fazila Rasaruddin, Fong, Sim Siong, Mohd Zuli Jaafar
    MyJurnal
    This paper outlines the application of chemometrics and pattern recognition tools to classify palm oil using Fourier Transform Mid Infrared spectroscopy (FT-MIR). FT-MIR spectroscopy is used as an effective analytical tool in order to categorise the oil into the category of unused palm oil and used palm oil for frying. The samples used in this study consist of 28 types of pure palm oil, and 28 types of frying palm oils. FT-MIR spectral was obtained in absorbance mode at the spectral range from 650 cm -1 to 4000 cm -1 using FT-MIR-ATR sample handling. The aim of this work is to develop fast method in discriminating the palm oils by implementing Partial Least Square Discriminant Analysis (PLS-DA), Learning Vector Quantisation (LVQ) and Support Vector Machine (SVM). Raw FT-MIR spectra were subjected to Savitzky-Golay smoothing and standardized before developing the classification models. The classification model was validated through finding the value of percentage correctly classified by test set for every model in order to show which classifier provided the best classification. In order to improve the performance of the classification model, variable selection method known as t-statistic method was applied. The significant variable in developing classification model was selected through this method. The result revealed that PLSDA classifier of the standardized data with application of t-statistic showed the best performance with highest percentage correctly classified among the classifiers.
    Matched MeSH terms: Spectrophotometry, Infrared
  12. Krisnaiah, Duduku, Yan, Yan Farm, Awang Bono, Noor Maizura Ismail, Lee, Muei Chng
    MyJurnal
    Synthesis of carboxymethylcellulose (CMC) from natural cellulose is an important industrial process. The effect of process parameters on the synthesis process is important information for the efficiency improvement of production process. Most of the previous studies on the effect of process parameters
    on the synthesis of CMC are based on the One-Factor-At-Time (OFAT); therefore, in this work, the response surface methodology (RSM) was used. Here, the cellulose was converted to CMC through
    carboxymethylation process using a technique of William etherification in heterogeneous system. The process parameters studied include the solvent ratio, reaction temperature and reactant ratio (molar ratio of NaOH to SMCA). Meanwhile, the analysis and optimization of the responses of the process, degree of substitution (DS) and yield were also performed using the response surface methodology. The validity of the synthesis process was identified by the determination of CMC spectrum using the fast Fourier infrared spectrometer (FTIR). The analysis of the results shows that carboxymethylation is strongly affected by combination of process parameters studied. The results obtained also show that the optimum responses, degree of substitution (DS) is 0.87 and yield is 1.80, whereas the optimum process parameters, solvent ratio is 0.70v/v, reaction temperature at 56.03oC, and molar ratio of NaOH to SMCA at 1.00mol/mol. These findings conclude that the DS and yield of carboxymethylation of cellulose are strongly affected by the combination of the process parameters.
    Matched MeSH terms: Spectrophotometry, Infrared
  13. Mohd Fudzi L, Zainal Z, Lim HN, Chang SK, Holi AM, Sarif Mohd Ali M
    Materials (Basel), 2018 Apr 29;11(5).
    PMID: 29710822 DOI: 10.3390/ma11050704
    Despite its large band gap, ZnO has wide applicability in many fields ranging from gas sensors to solar cells. ZnO was chosen over other materials because of its large exciton binding energy (60 meV) and its stability to high-energy radiation. In this study, ZnO nanorods were deposited on ITO glass via a simple dip coating followed by a hydrothermal growth. The morphological, structural and compositional characteristics of the prepared films were analyzed using X-ray diffractometry (XRD), field emission scanning electron microscopy (FESEM), and ultraviolet-visible spectroscopy (UV-Vis). Photoelectrochemical conversion efficiencies were evaluated via photocurrent measurements under calibrated halogen lamp illumination. Thin film prepared at 120 °C for 4 h of hydrothermal treatment possessed a hexagonal wurtzite structure with the crystallite size of 19.2 nm. The average diameter of the ZnO nanorods was 37.7 nm and the thickness was found to be 2680.2 nm. According to FESEM images, as the hydrothermal growth temperature increases, the nanorod diameter become smaller. Moreover, the thickness of the nanorods increase with the growth time. Therefore, the sample prepared at 120 °C for 4 h displayed an impressive photoresponse by achieving high current density of 0.1944 mA/cm².
    Matched MeSH terms: Spectrophotometry, Ultraviolet
  14. Shimi, G., Hasnah, H.
    MyJurnal
    This study aimed to determine the effect of cooking on phytate content and the inhibitory effects of phytate on the bioavailability of minerals in eight Malaysian soy based dishes. Phytate was analyzed by using anion-exchange chromatography while minerals were analyzed by using Atomic Absorption Spectrophotometer. Molar ratios were obtained by dividing the mole of phytate to minerals. Phytate content was reduced in cooked dishes compared to the raw ones but it was not significantly different (P > 0.05). Raw, cooked and whole dish soy products contained 257.14-900.00, 182.14-803.57 and 289.29-910.71 mg/100 g phytate, respectively. Boiling and steaming have reduced most phytate content in the food samples. Molar ratios for phytate/minerals in these samples (phytate/Ca >0.17; phytate/Fe >1) indicated that phytate content inhibited the absorption of calcium and iron. However, the ratio for Ca × phytate/Zn in all samples was less than 200 which showed that phytate did not affect the bioavailability of zinc.
    Matched MeSH terms: Spectrophotometry, Atomic
  15. Ariffin MM, Adiana G, Bidai J, Hing LS, Nurulnadia MY, Ong MC, et al.
    Data Brief, 2019 Dec;27:104806.
    PMID: 31788520 DOI: 10.1016/j.dib.2019.104806
    Metals are natural elements existed in the environment. However, due to the rapid development of urbanisation and economic, high content of anthropogenic metals are being perceived in polluting the environment. The oceans are known to be a part of the sinking basin for anthropogenic metals ends. Dataset provided is purposely to give an overview of dissolved metals spatial distribution in the South China Sea off the east Peninsular of Malaysia during the pre-, post- and Northeast (NE) Monsoon period. Seawater samples were collected in a grid of 18 stations at 3 different water depth. Dissolved metals were pre-concentrated on-board ship using Chelex-100 resin and analysed using Inductively Coupled Plasma Mass Spectrophotometry (ICPMS). The dataset shows the effect of NE Monsoon on dissolved metals spatial distribution mainly at the area closer to the land. Therefore, this dataset could reveal the past information on anthropogenic metals intrusion in the South China Sea, since Terengganu state was recently pointed to be one of the Malaysian waterfront city. Additionally, this dataset also could help in studying the cycle of metals in the southern South China Sea waters.
    Matched MeSH terms: Spectrophotometry
  16. Alya Nadhira Nasron, Ninna Sakina Azman, Nor Syaidatul Syafiqah Mohd Rashid, Nur Rahimah Said
    MyJurnal
    Degradation of azo dyes by using advanced oxidation processes (AOPs) was conducted. In this approach, different AOPs, which are Fenton process and titanium dioxide (TiO2) catalyst, were examined and compared for the degradation of an azo dye (i.e., Congo red dye). The sample was tested under UV light and the experiment was conducted for 90 min with 15 min interval. The degradation rate of dye was determined using UV-Vis spectrophotometry. The effect of several parameters on the degradation process such as the concentration of metal ions (Fe2+, Cu2+, and Mn2+) as the catalyst in Fenton process, the concentration of hydrogen peroxide (H2O2), the mass of TiO2, and pH value of the dye solution were investigated. The initial Congo red concentration used for both techniques was 5 ppm. The results showed that the percentage degradation followed the sequence of H2O2/Fe2+/UV, H2O2/Cu2+/UV, H2O2/Mn2+/UV, and TiO2/UV. The best operating conditions for H2O2/Fe2+/UV were pH 3, 0.2 M concentration of H2O2, and 0.02 M concentration of metal ion in 15 min, which achieved 99.92% degradation of dye. The Fourier transform infrared (FTIR) spectrum showed the absence of azo bond (N=N) peak after degradation process, which indicates the successful cleavage of azo bond in the chemical structure of Congo red.
    Matched MeSH terms: Spectrophotometry
  17. Noor Zuhartini Md Muslim, Musa Ahmad, Lee YH, Bahruddin Saad
    Sains Malaysiana, 2018;47:707-713.
    An optical fiber chemical sensor for the determination of free glutamate in food samples was fabricated based on the
    immobilization of 0.1 M copper(II) nitrate trihydrate onto sol-gel glass powder which was then mixed with methyl cellulose
    to form a pellet. A distinctive colour change from light blue to dark blue was observed in the presence of glutamate in
    less than 1 min. The colour change was measured by reflectance spectrophotometer at 691 nm. A linear relationship
    between the reflectance intensity and glutamate concentration was observed in the range of 12.5 to 500 mM with a limit
    of detection of 10.6 mM. This method is also reproducible with a relative standard deviation of less than 5%, no effect on
    pH of the glutamate solution and a good recovery of above 80%. The sensor was used for the determination of glutamate
    in common food items such as soups and flavor enhancers. The results obtained from the fabricated sensor were found
    to be comparable with HPLC method.
    Matched MeSH terms: Spectrophotometry
  18. Duman B, Erkmen C, Zahirul Kabir M, Ching Yi L, Mohamad SB, Uslu B
    PMID: 37257323 DOI: 10.1016/j.saa.2023.122907
    Binding mechanisms of two selected pesticides, propazine (PRO) and quinoxyfen (QUI) with bovine serum albumin (BSA) was examined using fluorescence, absorption and molecular docking methods. Intrinsic fluorescence of BSA was quenched in the presence of both PRO and QUI. The quenching was ascertained to be conversely linked to temperature, which suggested the contribution of static quenching process in the PRO-BSA and QUI-BSA complex formations. This results were validated by the enhancement in absorption spectrum of BSA upon binding with PRO and QUI. Binding constant values (Kf = 9.55-0.60 × 10-3 M-1 for PRO-BSA system; Kf = 7.08-5.01 × 102 M-1 for QUI-BSA system) and number of binding site (n) values for the PRO-BSA and QUI-BSA systems at different temperatures affirmed a weak binding strength with a set of equivalent binding sites on BSA. Thermodynamic data obtained for both the PRO-BSA and QUI-BSA interactions predicted that the association process was spontaneous and non-covalent contacts such as hydrophobic interactions, van der Waals forces and hydrogen bonds participated in the binding reactions. This result was further supported by the molecular docking assessments. Three-dimensional spectral results revealed the microenvironmental alterations near tryptophan (Trp) and tyrosine (Tyr) residues in BSA by the addition of PRO and QUI. The docking analysis demonstrated the binding pattern for the PRO-BSA and QUI-BSA systems and disclosed the preferred binding site of both PRO and QUI as site I (subdomain IIA) of BSA.
    Matched MeSH terms: Spectrophotometry, Ultraviolet
  19. Li B, Wu G, Yang X, Li Z, Albasher G, Alsultan N, et al.
    Environ Res, 2023 Jul 15;229:115781.
    PMID: 37076035 DOI: 10.1016/j.envres.2023.115781
    Endocrine disrupting chemicals (EDCs) have been extensively explored due to their harmful effects on individual health and the environment by interfering with hormone activity and disrupting the endocrine system. However, their relationship with essential trace elements remains uncertain. This research aimed to investigate the possible correlation between essential trace elements and toxic metals, including cadmium (Cd), and lead (Pb) in children aged 1-5 years with various infectious diseases, including gastrointestinal disorders, typhoid fever, and pneumonia. The study was conducted on biological testing and specimen (scalp hair and whole blood) of diseased and non-diseased children of the same residential area and referent/control age-matched children from developed cities consuming domestically treated water. The media of biological samples were oxidized by an acid mixture before being analyzed by atomic absorption spectrophotometry. The accuracy and validity of the methodology were verified through accredited reference material from scalp hair and whole blood sample. The study results revealed that diseased children had lower mean values of essential trace elements (iron, copper, and zinc) in both scalp hair and blood, except for copper, which was found to be higher in blood samples of diseased children. This implies that the deficiency of essential residue and trace elements in children from rural areas who consume groundwater is linked to various infectious diseases. The study highlights the need for more human biomonitoring of EDCs to better comprehend their non-classical toxic properties and their concealed costs on human health. The findings suggest that exposure to EDCs could be associated with unfavorable health outcomes and emphasizes the need for future regulatory policies to minimize exposure and safeguard the health of current and forthcoming generations of children. Furthermore, the study highlights the implication of essential trace elements in maintaining good health and their potential correlation with toxic metals in the environment.
    Matched MeSH terms: Spectrophotometry, Atomic
  20. Karunakaran T, Ee GC, Teh SS, Daud S, Mah SH, Lim CK, et al.
    Nat Prod Res, 2016 Jul;30(14):1591-7.
    PMID: 26710827 DOI: 10.1080/14786419.2015.1120727
    A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity.
    Matched MeSH terms: Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet
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